Device for facilitating the administration of a medicament to the lung by a catheter

Patent metadata

Field	Value
Publication number	US-11219730-B2
Application number	US-201615567578-A
Country	US
Kind code	B2
Filing date	Apr 27, 2016
Priority date	Apr 28, 2015
Publication date	Jan 11, 2022
Grant date	Jan 11, 2022

Abstract

A device (100) for facilitating the positioning of a catheter for the delivery of liquid medicament to spontaneously breathing patient, including: —an elongated main body (101) shaped to follow the internal shape of the patient's upper airways, the elongated main body (101) being provided with guiding means (107) adapted to house a catheter; —a substantially ring-shaped terminal element (103) adapted to engage the internal wall of the patient's retro-pharynx, the substantially ring-shaped terminal element (103) being connected to the elongated main body (101) by means of at least one spoke (105), the substantially ring-shaped element (103) and the at least one spoke (105) creating a chamber where the medicament can be delivered through the catheter.

First claim

The invention claimed is:

1. A device specifically adapted to position a catheter for the delivery of a liquid medicament in the form of a liquid pulmonary surfactant to the lungs of a spontaneously breathing patient, the device comprising:
an elongated main body shaped to follow an internal shape of the patient's upper airways, the elongated main body being provided with an internal channel adapted to house the catheter;
a substantially ring-shaped terminal element adapted to engage an internal wall of the spontaneously breathing patient's retro-pharynx, the substantially ring-shaped terminal element being connected to a distal end of the elongated main body by a plurality of spokes, the substantially ring-shaped terminal element and the plurality of spokes creating a chamber to receive delivery of the liquid pulmonary surfactant through the internal channel of the elongated main body, without impeding airflow through the spontaneously breathing patient's upper airways by way of one or more voids formed by the substantially ring-shaped terminal element and the plurality of spokes connecting the substantially ring-shaped terminal element to the distal end of the elongated main body; and
positioning means for fixing the device to the spontaneously breathing patient,
wherein the substantially ring-shaped terminal element has a widest part at a distal end of the device, the widest part of the substantially ring-shaped terminal element is wider than any portion of the elongated main body, the substantially ring-shaped terminal element is made of a material softer than the elongated main body, and the substantially ring-shaped terminal element includes an inflatable toroidal element ensuring the airflow through the spontaneously breathing patient's upper ways, and
wherein the positioning means include a substantially plate shaped element.

2. The device of claim 1 , wherein the inflatable toroidal element is spaced apart from and connected to the elongated main body by the plurality of spokes.

3. The device of claim 1 , wherein the inflatable toroidal element has a diameter between 0.5 and 5 mm.

4. The device of claim 1 , wherein a material of the elongated main body is selected from the group consisting of polyethylene (PET), polyvinyl chloride (PVC), and polyurethane (PU).

5. The device of claim 1 , wherein a material of the substantially ring shaped terminal element is selected from the group consisting of polyethylene (PET), polyvinyl chloride (PVC), polyurethane (PU), and medical-grade silicone.

6. The device of claim 1 , wherein the substantially ring-shaped terminal element has an elliptic shape.

7. The device of claim 1 , wherein the substantially ring-shaped terminal element includes two separate portions creating a non-continuous ring adapted for reducing contact with the spontaneously breathing patient's retro-pharynx.

8. The device of claim 1 , wherein the internal channel of the elongated main body defines an opening at the distal end of the elongated main body that leads directly to the chamber.

9. The device of claim 8 , wherein the internal channel has a diameter of 0.5 mm to 3 mm.

10. The device of claim 1 , wherein the elongated main body is flexible.

11. The device of claim 1 , wherein the positioning means is disposed on a second distal end of the elongated main body, the second distal end being opposite to the distal end.

12. A system for delivering a liquid pulmonary surfactant to a patient by a catheter specifically adapted to be positioned in the patient to deliver the liquid pulmonary surfactant to the lungs of a patient, wherein the system includes:
an elongated main body shaped to follow an internal shape of the patient's upper airways, the elongated main body being provided with an internal channel adapted to house the catheter;
a substantially ring-shaped terminal element adapted to engage an internal wall of the patient's retro-pharynx, the substantially ring-shaped terminal element being connected to a distal end of the elongated main body by at least one spoke, the substantially ring-shaped terminal element and the at least one spoke creating a chamber to receive delivery of the liquid pulmonary surfactant through the internal channel of the catheter, without impeding airflow through the patient's upper airways by way of one or more voids formed by the substantially ring-shaped terminal element and the at least one spoke connecting the substantially ring-shaped terminal element to the distal end of the elongated main body; and
positioning means for fixing the system to the spontaneously breathing patient,
wherein the substantially ring-shaped terminal element defines a second opening spaced from and at least partially aligned with a first opening of the internal channel at the distal end of the elongated main body, the second opening of the substantially ring-shaped terminal element has an inner diameter greater than an inner diameter of the first opening of the internal channel, the substantially ring-shaped terminal element is made of a material softer than the elongated main body, and the substantially ring-shaped terminal element includes an inflatable toroidal element ensuring the airflow through the spontaneously breathing patient's upper ways, and
wherein the positioning means include a substantially plate shaped element.

13. The system according to claim 12 , wherein the liquid pulmonary surfactant is selected from the group consisting of modified natural pulmonary surfactants, artificial surfactants, and reconstituted surfactants.

14. The system according to any claim 12 , wherein the patient is a spontaneously breathing pre-term neonate.

15. A method comprising:
positioning a catheter for the delivery of a liquid pulmonary surfactant to the lungs of a patient, with a device specifically adapted to facilitate positioning of the catheter for the delivery of the liquid pulmonary surfactant to the lungs of the patient, the device including:
an elongated main body shaped to follow an internal shape of the patient's upper airways, the elongated main body being provided with an internal channel adapted to house the catheter;
a substantially ring-shaped terminal element adapted to engage an internal wall of the patient's retro-pharynx, the substantially ring-shaped terminal element being connected to a distal end of the elongated main body by at least one spoke, the substantially ring-shaped terminal element and the at least one spoke creating a chamber to receive delivery of the liquid pulmonary surfactant through the internal channel of the elongated main body, without impeding airflow through the patient's upper airways by way of one or more voids formed by the substantially ring-shaped terminal element and the at least one spoke connecting the substantially ring-shaped terminal element to the distal end of the elongated main body; and
positioning means for fixing the device to the spontaneously breathing patient,
wherein the substantially ring-shaped terminal element defines a second opening spaced from and at least partially aligned with a first opening of the internal channel at the distal end of the elongated main body that leads directly to the chamber, the second opening of the substantially ring-shaped terminal element has an inner circumference greater than an inner circumference of the first opening of the internal channel, the substantially ring-shaped terminal element is made of a material softer than the elongated main body, and the substantially ring-shaped terminal element includes an inflatable toroidal element ensuring the airflow through the spontaneously breathing patie

Assignees

• Chiesi Farm Spa

Inventors

• Dellaca Raffaele
• Milesi Ilaria
• Zannin Emanuela

Classifications

• A61L31/06

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} · CPC title

• A61M16/0463 Primary

  combined with suction tubes, catheters or the like; Outside connections · CPC title

• A61M2209/06

  Packaging for specific medical equipment · CPC title

• A61M16/0434

  Cuffs · CPC title

• A61M16/0497 Primary

  Tube stabilizer · CPC title