Methods and systems for tissue damage identification and quantification

Patent metadata

Field	Value
Publication number	US-11211166-B2
Application number	US-201514851799-A
Country	US
Kind code	B2
Filing date	Sep 11, 2015
Priority date	Sep 12, 2014
Publication date	Dec 28, 2021
Grant date	Dec 28, 2021

Abstract

Example embodiments are described that relate to the analysis of tissue damage in an injured patient. Example embodiments are methods and systems for collecting medical imaging data, identifying tissue damage in the medical imaging data, analyzing the tissue damage shown in the medical imaging data, and/or quantifying the tissue damage shown in the medical imaging data. The disclosed methods allow for determining a risk for multiple organ failure and systemic inflammation in a multiply injured patient.

First claim

What is claimed is:

1. A method for determining a risk for multiple organ failure in an injured patient, the method comprising:
obtaining a medical image of a plurality of tissue injuries, wherein the plurality of tissue injuries comprises an axial anatomy tissue injury;
providing the medical image to an analytical system comprising: a memory device and a processor communicatively coupled to the memory device, and wherein the analytical system is programmed to:
calculate a volume measurement for each of the plurality of tissue injuries,
wherein the volume calculation is V=(4/3)r 3 π it and wherein r is determined by averaging three diameter measurements of the tissue injury and dividing by 2, the three diameter measurements consist essentially of a first measurement in the maximum axial dimension along the 804 axis, a second measurement perpendicular to the first measurement along the 802 axis, and a third measurement in the craniocaudal direction along the 806 axis;
sum the volume measurement for each of the plurality of tissue injuries to determine a total volume of tissue injury; and
determine a risk for multiple organ failure of the injured patient based on the total volume of tissue injury compared to a series of predetermined thresholds of total volume of tissue injury that correlate to different degrees of risk for multiple organ failure of the injured patient,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on a total volume of the axial anatomy tissue injury compared to a series of predetermined thresholds of total volume of axial tissue injury that correlate to different degrees of risk for multiple organ failure of the injured patient.

2. The method of claim 1 , wherein the medical image is selected from the group consisting of a radiographic image, a computed tomography (CT) scan, a magnetic resonance image (MRI), an x-ray, an ultrasound image, and combinations thereof.

3. The method of claim 1 , wherein the total volume of the axial anatomy tissue injury is from 1100 ml to 1750 ml,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on the total volume of the axial anatomy tissue injury being from 1100 ml to 1750 ml.

4. The method of claim 1 , wherein the plurality of tissue injuries comprises a torso tissue injury,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on a total volume of the torso anatomy tissue injury compared to a series of predetermined thresholds of total volume of torso tissue injury that correlate to different degrees of risk for multiple organ failure of the injured patient.

5. The method of claim 4 , wherein the total volume of the torso tissue injury is from 1000 ml to 1650 ml,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on the total volume of the torso tissue injury being from 1000 ml to 1650 ml.

6. The method of claim 1 , wherein the plurality of tissue injuries comprises an abdominopelvis tissue injury,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on a total volume of the abdominopelvis anatomy tissue injury compared to a series of predetermined thresholds of total volume of abdominopelvis tissue injury that correlate to different degrees of risk for multiple organ failure of the injured patient.

7. The method of claim 6 , wherein the total volume of the abdominopelvis tissue injury is from 650 ml to 1200 ml,
wherein determining the risk for multiple organ failure of the injured patient comprises determining the risk for multiple organ failure of the injured patient based on the total volume of the abdominopelvis tissue injury being from 650 ml to 1200 ml.

Assignees

• Univ Indiana Res & Tech Corp
• Indiana Univ Research & Technology Corp

Inventors

• Mckinley Todd O
• Steenburg Scott D

Classifications

• G16H50/20 Primary

  for computer-aided diagnosis, e.g. based on medical expert systems · CPC title

• G16H30/40

  for processing medical images, e.g. editing · CPC title

• G16H50/30

  for calculating health indices; for individual health risk assessment · CPC title