Reaction accelerating agent

Patent metadata

Field	Value
Publication number	US-11208675-B2
Application number	US-201716317209-A
Country	US
Kind code	B2
Filing date	Jul 13, 2017
Priority date	Jul 13, 2016
Publication date	Dec 28, 2021
Grant date	Dec 28, 2021

Abstract

Provided is a compound capable of accelerating the enzymatic reaction catalyzed by peroxidase. The present invention provides a peroxidase reaction accelerating agent comprising a compound represented by formula (I) and a method for measuring hydrogen peroxide using the same.

First claim

The invention claimed is:

1. A method for measuring hydrogen peroxide, comprising the step of using peroxidase and a peroxidase reaction accelerating agent,
wherein the peroxidase reaction accelerating agent is represented by any of the following formulae:

wherein
each X is independently selected from the group consisting of —H, —Na, —K, and —Li; and
each Y is independently selected from the group consisting of —H, —SO 3 X, and —COOX, or,
wherein the peroxidase reaction accelerating agent is represented by the following formula:

wherein
R 1 is a benzene ring or a naphthalene ring which may optionally be substituted with one or more substituents, wherein
the substituent(s) is selected from the group consisting of —SO 3 X, and

and
X is selected from the group consisting of —H, —Na, —K, and —Li.

2. The method according to claim 1 , wherein the peroxidase reaction accelerating agent is represented by any of the following formulae:

wherein
each X is independently selected from the group consisting of —H, —Na, —K, and —Li; and
each Y is independently selected from the group consisting of —H, —SO 3 X, and —COOX.

3. The method according to claim 1 , wherein the peroxidase reaction accelerating agent is represented by the following formula:

wherein
R 1 is a benzene ring or a naphthalene ring which may optionally be substituted with one or more substituents, wherein
the substituent(s) is selected from the group consisting of SO 3 X, and

and
X is selected from the group consisting of —H, —Na, —K, and —Li.

4. The method according to claim 1 , wherein the compound is a compound selected from the group consisting of a compound represented by the following formula (4-(phenylazo)phenol, CAS 1689-82-3):

a compound represented by the following formula:

wherein X is selected from the group consisting of —H, —Na, —K, and —Li,
a compound represented by the following formula:

wherein each X is independently selected from the group consisting of —H, —Na, —K, and —Li,
a compound represented by the following formula:

wherein each X is independently selected from the group consisting of —H, —Na, —K, and —Li,
and
a compound represented by the following formula:

wherein each X is independently selected from the group consisting of —H, —Na, —K, and —Li.

Assignees

• Kikkoman Corp

Inventors

• Ichiyanagi Atsushi
• Shimoji Kazuhiko

Classifications

• C09B29/02

  from diazotised o-amino-hydroxy compounds · CPC title

• C09B67/0083

  Solutions of dyes · CPC title

• C09B29/0803

  containing SO3H, OSO3H · CPC title

• C12Q1/28 Primary

  involving peroxidase · CPC title

• C09B29/0802

  containing COOH · CPC title