Drug delivery storage device and system

Patent metadata

Field	Value
Publication number	US-11207460-B2
Application number	US-201615775650-A
Country	US
Kind code	B2
Filing date	Dec 14, 2016
Priority date	Dec 14, 2015
Publication date	Dec 28, 2021
Grant date	Dec 28, 2021

Abstract

A drug delivery system includes a storage container defining one or more storage compartments and having at least one container sensor coupled thereto, a container condition change mechanism coupled to the storage container for imparting a change on one or more conditions of the one or more storage compartments, at least one drug delivery device adapted to deliver a drug to a user and adapted to be at least partially disposed within one or more of the one or more storage compartments, at least one delivery device sensor, a delivery device condition change mechanism coupled to the drug delivery device, and a controller coupled to the storage container. The storage container may be adapted to hold a number of drug delivery devices within a number of sealable storage compartments. The container sensor is adapted to sense a condition of the storage container, and the delivery device sensor is adapted to sense a condition of the at least one drug delivery device. The controller is adapted to instruct the container condition change mechanism and/or the delivery device change mechanism to impart a change on at least one condition of the storage container and/or the drug delivery device.

First claim

What is claimed is:

1. A drug delivery system comprising:
a storage container defining one or more storage compartments;
at least one container sensor coupled to the storage container for sensing a condition of the at least one storage compartment;
a container condition change mechanism coupled to the storage container for imparting a change on one or more conditions of the one or more storage compartments;
at least one drug delivery device adapted to deliver a drug to a user and adapted to be at least partially disposed within one or more of the one or more storage compartments of the storage container;
at least one delivery device sensor coupled to the at least one drug delivery device for sensing a condition of the at least one drug delivery device;
a delivery device condition change mechanism coupled to the at least one drug delivery device for imparting a change on one or more conditions of the at least one drug delivery device; and
a controller coupled to the storage container and in communication with the at least one container sensor, and in communication with the at least one delivery device sensor when the at least one drug delivery device is disposed in one or more of the one or more storage compartments of the storage container,
wherein the controller includes a memory, a processor, and computer-executable instructions stored on the memory and executable by the processor to instruct at least one of (a) or (b):
(a) the container condition change mechanism to impart a change on the one or more conditions of the one or more storage compartments of the storage container,
(b) the delivery device condition change mechanism to impart a change on the one or more conditions of the at least one drug delivery device.

2. The drug delivery system of claim 1 , wherein the at least one container sensor comprises at least one of:
(a) a proximity sensor coupled to the storage container for sensing at least one of (i) a presence of the at least one drug delivery device and (ii) whether the storage container is in an open configuration,
(b) a pressure sensor conductive switch disposed within the storage container for sensing whether the drug delivery device is disposed within the storage container,
(c) a temperature sensor coupled to the storage container for sensing at least one of an external temperature and an internal temperature of the storage container,
(d) a superelastic material adapted to engage a circuit when the storage container is within a temperature threshold, and
(e) a humidity sensor for sensing a humidity within the one or more compartments of the storage container.

3. The drug delivery system of claim 1 , wherein the at least one delivery device sensor comprises at least one of:
(a) a temperature sensor for sensing a temperature of a drug stored in a reservoir of the drug delivery device,
(b) a switch for detecting the position of a locking mechanism associated with an actuator of the drug delivery device,
(c) a switch for detecting the position of a plunger mechanism associated with an actuator of the drug delivery device,
(d) a switch for detecting the position of a needle cap on the drug delivery device,
(e) a photo sensor for detecting at least one of an opacity and a color of a drug stored in a reservoir of the drug delivery device.

4. The drug delivery system of claim 1 , wherein the container condition change mechanism comprises at least one of:
(a) a heating mechanism adapted to raise the temperature of the one or more storage compartments,
(b) a cooling mechanism adapted to lower the temperature of the one or more storage compartments,
(c) a locking mechanism adapted to selectively restrict and permit access to the one or more storage compartments,
(d) a vacuum pump mechanism adapted to draw a vacuum on one or more of the one or more storage compartments of the storage container,
(e) a lock mechanism associated with selectively enabling access to one or more of the one or more storage compartments of the storage container,
(f) a communication device adapted to communicate information relating to the drug delivery system.

5. The drug delivery system of claim 1 , wherein the delivery device condition change mechanism comprises at least one of:
(a) a locking mechanism adapted to selectively enable use of the drug delivery device,
(b) a heating mechanism adapted to raise the temperature of at least a portion of the drug delivery device,
(c) a cooling mechanism adapted to lower the temperature of at least a portion of the drug delivery device,
(d) a communication device adapted to communicate information relating to the drug delivery system.

6. The drug delivery system of claim 1 , wherein each of the one or more storage compartments of the storage container includes a sealing mechanism to selectively seal the storage compartment.

7. The drug delivery system of claim 1 , wherein the storage container comprises a plurality of sealable storage compartments and a plurality of container sensors, each container sensor associated with one of the plurality of sealable storage compartments.

8. The drug delivery system of claim 1 , wherein the plurality of sealable storage compartments are thermally isolated from each other.

9. The drug delivery system of claim 1 , further comprising:
a first communication module coupled to the storage container; and
a computing device located separate from the storage container and the at one least drug delivery device, the computing device having a memory, a processor, computer-executable instructions stored on the memory, and a second communication module adapted to communicate with the first communication module;
wherein the controller instructs the first communication module to transmit a signal to the second communication module of the computing device and wherein the computing device is adapted to determine and transmit a corresponding signal via the second communication module to the first communication module to instruct the at least one of (a) or (b), as recited in claim 1 :
(a) the container condition change mechanism to impart a change on the one or more conditions of the one or more storage compartments of the storage container,
(b) the delivery device condition change mechanism to impart a change on the one or more conditions of the at least one drug delivery device.

10. The drug delivery system of claim 9 , wherein the storage container is adapted to restrict the first communication module from transmitting the signal to the computing device when the storage container is in a closed configuration.

11. The drug delivery system of claim 9 , wherein the first communication module transmits the signal via a wireless communication protocol.

12. The drug delivery system of claim 9 , wherein the signal transmitted to the computing device includes information relating to at least one of:
(a) a temperature excursion experienced within the storage container,
(b) a frequency of use of the delivery device, and
(c) a quantity of unused delivery devices.

13. A method for managing a plurality of drug delivery devices stored in a plurality of compartments in a storage container, the method comprising:
obtaining a sensing condition data of at least one storage compartment;
obtaining a container condition change data for imparting a change of one or more conditions data for each of the plurality of compartments of said storage container;
obtaining a drug delivery device condition data of each drug delivery device;
obtaining a delivery device condition change data for imparting a change of one or more conditions data for each of the plurality of drug delivery d

Assignees

• Amgen Inc

Inventors

• Tamtoro Ferry
• Yang Huaying
• Gibson Scott Robert
• Busby Donald
• Shultz Peter V
• Taha Basel Hasan
• Mccullough Adam B

Classifications

• A61M2205/3368

  Temperature · CPC title

• G16H20/17

  delivered via infusion or injection · CPC title

• A61M2205/0216

  Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking · CPC title

• A61J7/0409

  with timers · CPC title

• A61J7/0481

  working on a schedule basis · CPC title