Optical test platform

Patent metadata

Field	Value
Publication number	US-11192112-B2
Application number	US-202016815585-A
Country	US
Kind code	B2
Filing date	Mar 11, 2020
Priority date	Apr 20, 2017
Publication date	Dec 7, 2021
Grant date	Dec 7, 2021

Abstract

Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

First claim

The invention claimed is:

1. A test platform for facilitating the optical interrogation of a test sample, the test platform comprising:
a shell defining:
a cavity for receiving at least a portion of a sample tube;
a first aperture;
a second aperture;
a sealed distal end; and
a proximal end opposite the sealed distal end;

a first window sealing the first aperture; and
a second window sealing the second aperture,
wherein the first window and the second window are optically coupled via the cavity, and
wherein the shell is watertight at least from the sealed distal end to and including the first aperture and the second aperture.

2. The test platform of claim 1 , wherein the proximal end opposite the sealed distal end defines an opening configured to removably receive the portion of the sample tube therethrough.

3. The test platform of claim 1 further comprising a third window sealing a third aperture of the shell, wherein the shell is watertight at least from the sealed distal end to and including the third aperture.

4. The test platform of claim 3 , wherein the first window and the second window are aligned opposite each other relative to the cavity, such that a first axis extending between the first window and the second window intersects a second axis extending between the sealed distal end and the proximal end of the shell along a center of the cavity.

5. The test platform of claim 4 , wherein the third window is perpendicular to the first window and the second window, such that a third axis extending perpendicular to a face of the third window intersects the second axis perpendicular to the first axis.

6. The test platform of claim 3 , wherein the first window and the second window are parallel to each other and the third window is perpendicular to the first window and the second window.

7. The test platform of claim 3 , wherein the first window, the second window, and the third window each intersect a plane defined perpendicular to an axis extending between the sealed distal end and the proximal end.

8. The test platform of claim 1 , further comprising a fourth window sealing a fourth aperture, wherein the fourth aperture is defined at the sealed distal end and is configured to seal the sealed distal end, and wherein the fourth window faces the proximal end.

9. The test platform according to claim 8 , wherein the fourth window is non-circular.

10. The test platform of claim 8 , further comprising an illumination light disposed outside the cavity, the illumination light configured to emit electromagnetic radiation through the fourth window into the cavity and out an opening at the proximal end of the shell.

11. The test platform of claim 1 , further comprising:
an emitter disposed outside the cavity, the emitter configured to emit electromagnetic radiation through the first window into the cavity; and
a detector disposed outside the cavity, the detector configured to receive the electromagnetic radiation through the second window from the cavity.

12. The test platform of claim 11 , wherein the shell defines a detector mount configured to engage the detector and prevent other electromagnetic radiation from impinging the detector from a direction other than through the second window.

13. The test platform of claim 1 , wherein the shell further comprises at least two alignment ribs between the sealed distal end and the proximal end, wherein the alignment ribs are configured to engage the sample tube in an instance in which the cavity receives the portion of the sample tube.

14. The test platform of claim 13 , further comprising a spring configured to apply a force on the sample tube in the instance in which the cavity receives the portion of the sample tube, wherein the force is applied along an axis extending between the at least two alignment ribs.

15. The test platform of claim 13 , wherein the shell further defines a guide surface configured to cooperate with the at least two alignment ribs to align the sample tube along an axis extending between the sealed distal end and the proximal end.

16. The test platform of claim 15 , wherein the guide surface defines a U-shape.

17. The test platform of claim 1 , wherein the shell further defines a guide surface proximate the sealed distal end, wherein the guide surface is configured to engage the sample tube in an instance in which cavity receives the portion of the sample tube.

18. The test platform of claim 1 , further comprising a spring configured to apply a force on the sample tube in an instance in which the cavity receives the portion of the sample tube.

19. The test platform of claim 18 , wherein the spring comprises a first leg and a second leg, wherein the first leg and the second leg are configured to apply the force on a sample tube towards a point between the first leg and the second leg.

20. The test platform of claim 18 , wherein the spring is configured to apply the force perpendicular to an axis extending between the sealed distal end and the proximal end.

21. The test platform of claim 1 , further comprising a third aperture defined at the sealed distal end and configured to seal the sealed distal end.

22. The test platform of claim 1 , wherein the first window and the second window are aligned opposite each other relative to the cavity, such that a first axis extending between the first window and the second window intersects a second axis extending between the sealed distal end and the proximal end of the shell along a center of the cavity.

23. A optical density instrument configured to measure an optical density of a sample in a sample tube, the optical density instrument comprising the optical test platform of claim 1 .

Assignees

• Bio Merieux Inc

Inventors

• Hoffmann Jr Jack R
• Maes Gregory R
• Price Jeffrey Edward
• Bullock Jared Ian
• Crandall Samuel B
• Yam Jacky S
• Kocher Christopher George
• Clynes Walter J

Classifications

• G01N2201/12707

  Pre-test of apparatus, e.g. dark test, sensor test · CPC title

• G01N33/487

  of liquid biological material · CPC title

• B01L2200/14

  Process control and prevention of errors · CPC title

• G01N21/0303

  Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment (G01N21/031 - G01N21/15 take precedence) · CPC title

• G01N21/4738

  Diffuse reflection (precedence is given to G01N21/55 - G01N21/57 if specular component is taken into consideration), e.g. also for testing fluids, fibrous materials · CPC title