Treatment of helicobacter pylori infections

US11186575B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11186575-B2
Application numberUS-201314419669-A
CountryUS
Kind codeB2
Filing dateAug 7, 2013
Priority dateAug 7, 2012
Publication dateNov 30, 2021
Grant dateNov 30, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Methods of treating infections due to Helicobacter pylori ( H. pylori ), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering to the subject an inhibitor of H. pylori MTAN (5′-methylthioadenosine nucleosidase) having the structure of formula (I)

First claim

Opening claim text (preview).

What is claimed is: 1. A compound selected from the group consisting of or a pharmaceutically acceptable salt thereof, or an ester thereof. 2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier. 3. A method of treating a Helicobacter pylori ( H. pylori ) infection in a subject in need thereof comprising administering to the subject a compound of claim 1 in an amount effective to inhibit growth of H. pylori. 4. The method of claim 3 , wherein the subject has a peptic ulcer. 5. The method of claim 3 , wherein the subject has a gastric ulcer or a duodenal ulcer. 6. The method of claim 3 , wherein the compound is administered orally.

Assignees

Inventors

Classifications

  • Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change · CPC title

  • C07D487/04Primary

    Ortho-condensed systems · CPC title

  • ortho- or peri-condensed with heterocyclic rings · CPC title

  • for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants · CPC title

  • Antibacterial agents · CPC title

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Frequently asked questions

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What does patent US11186575B2 cover?
Methods of treating infections due to Helicobacter pylori ( H. pylori ), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering to the subject an inhibitor of H. pylori MTAN (5′-methylthioadenosine nucleosidase) having the structure of formula (I)
Who is the assignee on this patent?
Albert Einstein College Medicine Inc, Victoria Link Ltd, Alber Einslein College of Medicine
What technology area does this patent fall under?
Primary CPC classification C07D487/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).