Hydrocarbon oil for a therapeutic use

Patent metadata

Field	Value
Publication number	US-11179347-B2
Application number	US-201816495713-A
Country	US
Kind code	B2
Filing date	Mar 16, 2018
Priority date	Mar 20, 2017
Publication date	Nov 23, 2021
Grant date	Nov 23, 2021

Abstract

A hydrocarbon oil intended to be used as a drug including a content by weight of isoparaffins ranging from 90 to 100%, a content by weight of normal paraffins ranging from 0 to 10% and having a content of carbon of biological origin greater than or equal to 90% relative to the total weight of the hydrocarbon oil.

First claim

The invention claimed is:

1. A method for the treatment of skin diseases and/or wound healing disorders comprising administering a hydrocarbon oil as an antioxidant and/or anti-radical agent and/or anti-inflammatory agent and/or anti-apoptotic, the hydrocarbon oil comprising a content by weight of isoparaffins ranging from 90 to 100%, a content by weight of normal paraffins ranging from 0 to 10% and having a content of carbon of biological origin greater than or equal to 90% relative to the total weight of the hydrocarbon oil.

2. The method according to claim 1 , comprising a topical administration.

3. The method according to claim 1 , comprising a systemic administration.

4. The method according to claim 1 , wherein the hydrocarbon oil comprises a content by weight of isoparaffins ranging from 95% to 100% relative to the total weight of the hydrocarbon oil.

5. The method according to claim 1 , wherein the hydrocarbon oil is chosen from among non-cyclic isoparaffins comprising from 14 to 18 carbon atoms.

6. The method according to claim 1 , wherein:
the hydrocarbon oil comprises a content by weight of normal paraffins less than or equal to 5% relative to the total weight of the hydrocarbon oil; and/or
the hydrocarbon oil comprises a content by weight of naphthenic compounds less than or equal to 1%, relative to the total weight of the hydrocarbon oil; and/or
the hydrocarbon oil comprises a content by weight of aromatic compounds less than or equal to 500 ppm relative to the total weight of the hydrocarbon oil.

7. The method according to claim 1 , wherein:
the hydrocarbon oil has a boiling temperature ranging from 230 to 340° C., according to the standard ASTM D86; and/or
the hydrocarbon oil has a flash point greater than or equal to 110° C. according to the standard EN ISO 2719; and/or
the hydrocarbon oil has a vapour pressure at 20° C. less than or equal to 0.01 kPa.

8. The method according to claim 1 , wherein the hydrocarbon oil is obtained by a method of catalytic hydrogenation at a temperature from 80 to 180° C. and at a pressure from 50 to 160 bars of a deoxygenated and/or isomerised feedstock of biological origin.

9. The method according to claim 1 , wherein the hydrocarbon oil is administered in the form of a pharmaceutical composition comprising at least the hydrocarbon oil.

10. The method according to claim 9 , wherein the pharmaceutical composition comprises at least one fatty substance chosen from among: vegetable oils, hydrocarbon oils other than said hydrocarbon oil, vegetable butters, fatty alcohols and ethers, oily esters, alkanes and silicone oils and/or at least one additive.

11. The method according to claim 9 , wherein the pharmaceutical composition is an anhydrous composition, an emulsion such as a water-in-oil emulsion (W/O), an oil-in-water emulsion (O/W) or a multiple emulsion, a nano-emulsion, or a dispersion or a gel.

12. The method according to claim 1 , wherein the hydrocarbon oil is administered in the form of a medical food comprising at least the hydrocarbon oil.

13. The method according to claim 1 , wherein the hydrocarbon oil is administered in combination with a compound chosen from among quaternary ammoniums, aromatic alcohols and isothiazolinones.

14. The method according to claim 13 , wherein the compound is chosen from among quaternary ammoniums.

15. The method according to claim 13 , wherein the compound represents from 0.1 ppm to 40% by weight of the administered composition.

16. The method according to claim 1 , for the treatment of skin diseases selected from psoriasis, corns and warts, acne, seborrheic disorders, herpes, mycoses, eczema, shingles.

17. The method according to claim 9 , wherein the hydrocarbon oil is administered in the form of a pharmaceutical composition comprising at least the hydrocarbon oil, in a quantity ranging from 0.5 to 80% by weight relative to the total weight of the pharmaceutical composition.

18. The method according to claim 12 , wherein the hydrocarbon oil is administered in the form of a medical food comprising at least the hydrocarbon oil in a quantity ranging from 0.5 to 80% by weight relative to the total weight of the medical food.

19. A method for the treatment of skin diseases and/or wound healing disorders comprising administering a hydrocarbon oil as a drug, the hydrocarbon oil comprising a content by weight of isoparaffins ranging from 90 to 100%, a content by weight of normal paraffins ranging from 0 to 10% and having a content of carbon of biological origin greater than or equal to 90% relative to the total weight of the hydrocarbon oil, wherein the hydrocarbon oil has a biodegradability at 28 days of at least 60%.

Assignees

• Total Marketing Services

Inventors

• Swoboda Benjamin
• Lemaire Philippe

Classifications

• A61K47/10

  Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61K47/18

  Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids · CPC title

• A61K9/107

  Emulsions {; Emulsion preconcentrates; Micelles (composition of emulsions A61K47/00)} · CPC title

• A23L2/00

  Non-alcoholic beverages; Dry compositions or concentrates therefor (soup concentrates A23L23/10); Preparation or treatment thereof (preparation of non-alcoholic beverages by removal of alcohol C12H3/00) · CPC title