Hygienic medical devices having hydrophilic coating

Patent metadata

Field	Value
Publication number	US-11167064-B2
Application number	US-201716317724-A
Country	US
Kind code	B2
Filing date	Jul 13, 2017
Priority date	Jul 14, 2016
Publication date	Nov 9, 2021
Grant date	Nov 9, 2021

Abstract

Hygienic Hydrophilic coatings, hydrophilic coating formulations and wetting fluids that include an anti-infective agent.

First claim

What is claimed is:

1. A hygienic medical device, comprising:
a surface; and
a lubricious hydrophilic coating disposed on the surface, wherein the coating comprises a hydrophilic polymer matrix and an anti-infective agent comprising mannose that is located within the hydrophilic polymer matrix.

2. The hygienic medical device of claim 1 wherein the hydrophilic polymer matrix comprises polyvinylpyrrolidone.

3. The hygienic medical device of claim 1 wherein the coating further comprises a peroxide generating enzyme.

4. The hygienic medical device of claim 3 wherein the enzyme comprises an oxidoreductase.

5. The hygienic medical device of claim 3 wherein the enzyme comprises glucose oxidase.

6. The hygienic medical device of claim 3 wherein the enzyme comprises peroxidase.

7. The hygienic medical device of claim 6 wherein the peroxidase comprises lactoperoxidase.

8. The hygienic medical device of claim 1 wherein the coating further comprises a thixotropic agent.

9. The hygienic medical device of claim 8 wherein the thixotropic agent comprises pectin, agar and/or alginate.

10. The hygienic medical device of claim 1 wherein the coating further including sugar alcohol.

11. The hygienic medical device of claim 1 wherein the coating further comprises an organic acid.

12. The hygienic medical device of claim 1 wherein the coating further comprises an antioxidant.

13. A catheter, comprising:
a surface; and
a lubricious hydrophilic coating disposed on the surface, wherein the coating comprises a hydrophilic polymer matrix; and
a solution of anti-infective agent comprising mannose, the solution being located within the hydrophilic polymer matrix.

14. The catheter of claim 13 wherein the hydrophilic polymer matrix comprises polyvinylpyrrolidone.

15. The catheter of claim 13 wherein the solution further comprises a peroxide generating enzyme.

16. The catheter of claim 15 wherein the enzyme comprises an oxidoreductase.

17. The catheter of claim 15 wherein the enzyme comprises glucose oxidase.

18. The catheter of claim 15 wherein the enzyme comprises peroxidase.

19. The catheter of claim 18 wherein the peroxidase comprises lactoperoxidase.

20. The catheter of claim 13 wherein the solution further comprises a thixotropic agent.

21. The catheter of claim 20 wherein the thixotropic agent comprises pectin, agar and/or alginate.

22. The catheter of claim 13 wherein the solution further including sugar alcohol.

23. The catheter of claim 13 wherein the solution further comprises an organic acid.

24. The catheter of claim 13 wherein the solution further comprises an antioxidant.

Assignees

• Hollister Inc

Inventors

• Farrell David J
• O'Mahony John P
• Fitzpatrick James J
• O'Flynn Padraig M
• Fletter Paul C
• Arnold William K
• Clarke John T
• Foley Adam J
• Cullum Malford E

Classifications

• A61L2300/232

  Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides · CPC title

• A61L2300/254

  Enzymes, proenzymes · CPC title

• A61L29/005

  Ingredients of undetermined constitution or reaction products thereof · CPC title

• A61L31/10

  Macromolecular materials · CPC title

• A61L31/16

  Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)} · CPC title