Method for reducing biofilm formation

Patent metadata

Field	Value
Publication number	US-11147570-B2
Application number	US-201916269229-A
Country	US
Kind code	B2
Filing date	Feb 6, 2019
Priority date	Nov 12, 2014
Publication date	Oct 19, 2021
Grant date	Oct 19, 2021

Abstract

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

First claim

What is claimed is:

1. A medical therapeutic method comprising:
removing necrotic tissue and undesired organic material from a surgical site on a patient;
after the removal of all discernible necrotic tissue and undesirable organic material from the surgical site and while the surgical site is free of discernible bacteria, placing at least one ultrasonic transducer on the patient at least proximate the surgical site; and
after the placing of said transducer and while said transducer is in effective vibration-transmitting contact with the patient, conducting an electrical energization waveform of an ultrasonic frequency to said transducer at least intermittently during a period of approximately one day or longer, said waveform having frequency, amplitude and duration to effectively reduce biofilm formation on the patient at the surgical site and thereby facilitate a healing of the patient's tissue at the surgical site.

2. The method defined in claim 1 wherein the placing of said transducer includes removably attaching said transducer to the patient.

3. The method defined in claim 2 wherein the placing of said transducer includes removably attaching said transducer atop tissues at the surgical site.

4. The method defined in claim 2 wherein said transducer is affixed to a carrier pad, the placing of said transducer on the patient including attaching said pad to the patient.

5. The method defined in claim 1 wherein the removing of necrotic tissues includes operating an ultrasonic debrider instrument at a first energy setting, further comprising utilizing said instrument at a lower second energy setting to pre-condition the tissues at the surgical site for disrupting adherence or starting the formation of biofilm.

Assignees

• Misonix Inc

Inventors

• Mikus Paul
• Isola Scott
• Voic Dan
• Ludecker Scott
• Darian Alexander

Classifications

• A61B17/320068

  using mechanical vibrations, e.g. ultrasonic (A61B17/22012 takes precedence; dental tooth drilling devices operated by vibration A61C3/03; removing intra-ocular material using mechanical vibrations A61F9/00745) · CPC title

• A61M1/85

  with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants (for negative pressure wound therapy A61M1/92, A61M1/94; combined with tracheal tubes A61M16/0463; dental instruments with combined rinsing and aspirating A61C17/0208) · CPC title

• A61B2217/005

  with suction drainage system · CPC title

• A61B2017/320084

  Irrigation sleeves · CPC title

• A61M2205/058

  with ultrasound therapy · CPC title