Vascular remodeling device

Patent metadata

Field	Value
Publication number	US-11147563-B2
Application number	US-201816002784-A
Country	US
Kind code	B2
Filing date	Jun 7, 2018
Priority date	Mar 25, 2011
Publication date	Oct 19, 2021
Grant date	Oct 19, 2021

Abstract

A vascular remodeling device is provided. The device has an anchor portion, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. The device also includes a distal portion sized for deployment in a blood vessel. The distal portion is radially expandable from a collapsed state to an expanded state and has a distal face that is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function in an aneurysm neck. The device also has an intermediate portion that interconnects a distal end of the anchor portion and a proximal end of the distal portion. In some embodiments, the anchor portion and/or distal portion has a plurality of interconnected struts.

First claim

We claim:

1. A vascular remodeling device, comprising:
an anchor portion sized for deployment in a blood vessel, the anchor portion radially expandable from a collapsed state to an expanded state such that, when expanded in a blood vessel, the anchor portion engages a wall of the vessel, the anchor portion having a first end region, a second end region, a longitudinal axis extending through the first and second end regions, and a plurality of anchor struts formed from single tube or sheet and extending between the first and second end regions, wherein the anchor struts converge toward the longitudinal axis at the first and second end regions, the anchor portion including a first waist comprising the radially largest region of the anchor portion when in the expanded state, wherein the anchor portion is configured to permit blood flow therethrough without significant impediment;
a distal portion sized and configured for deployment in a junction of two or more human blood vessels, the distal portion radially expandable from a collapsed state to an expanded state and having a second waist comprising the radially largest region of the distal portion when in the expanded state, the distal portion having a distal face, located distal to the second waist, sized and configured to occlude an aneurysm adjacent the junction when the second waist is in the junction and the distal portion is in the expanded state, the distal portion further having a proximal face, located proximal to the second waist, configured to permit blood flow therethrough without significant impediment, the distal face having a lower porosity than the proximal face; and
an intermediate portion that interconnects a distal end of the anchor portion and a proximal end of the distal portion, the intermediate portion being the radially narrowest region of the device between the first waist and the second waist, the anchor portion and distal portion being able to pivot relative to each other at or near the intermediate portion such that a central axis of the anchor portion and a central axis of the distal portion are not coaxial.

2. The device of claim 1 , wherein the intermediate portion comprises a radially central region of the device.

3. The device of claim 1 , wherein the distal portion comprises a plurality of distal struts that extend radially outward toward the second waist.

4. The device of claim 3 , wherein the distal struts extend distally away and radially outwardly from the intermediate portion toward the second waist, and further extend distally away and radially inwardly from the second waist toward a radially central region of the device.

5. The device of claim 3 , wherein the distal struts each have a proximal end and a distal end, and the distal struts are not joined to each other anywhere along their length between their proximal and distal ends.

6. The device of claim 3 , wherein the distal struts extend distally and radially inwardly from the second waist to form the distal face of the distal portion.

7. The device of claim 6 , wherein the distal struts each have a proximal end and a distal end, and the distal struts are not joined to each other anywhere along their length between their proximal and distal ends, and wherein the distal struts forming the distal face of the distal portion have widened portions, the widened portions configured to increase an occlusiveness of the distal face.

8. The device of claim 3 , wherein the distal struts taper inward as they extend proximally from the second waist toward the intermediate portion.

9. The device of claim 3 , wherein a proximal end of each distal strut is joined to the intermediate portion.

10. The device of claim 1 , wherein the anchor struts extend radially outward toward the first waist and the distal portion comprises a plurality of distal struts that extend radially outward toward the second waist.

11. The device of claim 10 , wherein the distal struts are independent of the anchor struts.

12. The device of claim 1 , wherein the anchor portion and distal portion are able to pivot multiaxially relative to each other.

13. The device of claim 1 , wherein:
the anchor portion forms a distal face located distal to the first waist;
the distal face of the anchor portion tapers radially inward as it extends distally from the first waist to join the intermediate portion; and
the proximal face of the distal portion tapers radially inward as it extends proximally from the second waist to join the intermediate portion.

14. The device of claim 13 , wherein the intermediate portion is confined in a radially central region of the device.

15. The device of claim 13 , wherein the proximal face of the distal portion comprises a plurality of radially expandable distal struts and the distal face of the anchor portion comprises the anchor struts.

16. The device of claim 15 , wherein the intermediate portion, the anchor struts, and the distal struts are all formed from a single sheet or tube of material.

17. The device of claim 16 , wherein the intermediate portion comprises an uncut portion of the single sheet or tube of material.

18. The device of claim 17 , wherein the anchor portion and distal portion are able to pivot multiaxially relative to each other without plastic deformation of the intermediate portion.

19. The device of claim 1 , wherein the anchor portion, intermediate portion, and distal portion are all formed from a single sheet or tube of material.

20. The device of claim 1 , wherein:
the anchor portion forms a distal face located distal to the first waist;
and both the distal face of the anchor portion and the proximal face of the distal portion are less occlusive than the distal face of the distal portion.

21. The device of claim 20 , wherein the anchor portion forms a proximal face located proximal to the first waist, and the proximal face of the anchor portion is less occlusive than the distal face of the distal portion.

22. The device of claim 20 , wherein the distal face of the anchor portion is configured not to impede blood flow significantly.

23. The device of claim 20 , wherein the distal face of the distal portion is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function at the aneurysm.

24. The device of claim 1 , wherein the distal face, when positioned adjacent the aneurysm, at least one of (a) supports a therapeutically effective amount or density of aneurysm-filling materials or devices in an aneurysm, (b) promotes thrombogenesis, and (c) diverts flow.

25. A vascular remodeling device, comprising:
an anchor portion sized for deployment in a blood vessel, the anchor portion radially expandable from a collapsed state to an expanded state such that, when expanded in a blood vessel, the anchor portion engages a wall of the vessel, the anchor portion having a first waist comprising the radially largest region of the anchor portion when in the expanded state, the anchor portion configured to permit blood flow therethrough without significant impediment; and
a distal portion sized for deployment in a junction of two or more human blood vessels, the distal portion comprising a first end region, a second end region, a longitudinal axis extending through the first and second end regions, and a plurality of distal struts formed from a single tube or sheet and extending between the first and second end regions, wherein the distal struts converge t

Assignees

• Covidien Lp

Inventors

• Molaei Masoud
• Epstein Evan
• Newell Gabriel
• Tran Quang

Classifications

• A61B17/12172

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title

• A61F2/07

  Stent-grafts · CPC title

• A61B2017/00526

  Methods of manufacturing · CPC title

• A61B17/12118 Primary

  for positioning in conjunction with a stent · CPC title