Glass containers with delamination resistance and improved damage tolerance
US-2020375846-A1 · Dec 3, 2020 · US
US11137206B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11137206-B2 |
| Application number | US-202016736092-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 7, 2020 |
| Priority date | Jun 9, 2014 |
| Publication date | Oct 5, 2021 |
| Grant date | Oct 5, 2021 |
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Embodiments of methods, systems, and apparatuses for lyophilizing, storing, and transfusing materials are described. In embodiments, the materials may include whole blood or a component of whole blood such as plasma.
Opening claim text (preview).
What is claimed is: 1. A method of lyophilizing material, the method comprising: maintaining a material in a container; subjecting the material to a first pressure; evaporating at least a portion of a liquid component of the material while adding thermal energy to the material; cooling the material to freeze any remaining liquid component into a solid; pressing the material during the cooling by physical contact between a pressing means and an upper portion of the container and and physical contact between the upper portion of the container and the material thereby controlling a cross-section of the material to reduce variation in cross section of the material; subjecting the material to a second pressure which is less than the first pressure; and sublimating a portion of the solid while adding thermal energy to the material. 2. The method of claim 1 , wherein the sublimating comprises adding IR energy to the material. 3. The method of claim 1 wherein the pressing means is a shelf system. 4. The method of claim 1 wherein the pressing means is a flexible bladder. 5. The method of claim 4 wherein the flexible bladder may be filled with a fluid.
Blood or products thereof · CPC title
Pressure processes, e.g. following predefined pressure changes over time · CPC title
Temperature processes, e.g. following predefined temperature changes over time · CPC title
Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving · CPC title
for temperature control, e.g. refrigerators or freeze-drying apparatus · CPC title
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