Lattice microfluidics

Patent metadata

Field	Value
Publication number	US-11130131-B2
Application number	US-201916584460-A
Country	US
Kind code	B2
Filing date	Sep 26, 2019
Priority date	Sep 26, 2019
Publication date	Sep 28, 2021
Grant date	Sep 28, 2021

Abstract

An engineered unit cell is disclosed for flowing a fluid therethrough in three dimensions. The unit cell may have a substrate with a plurality of flow channels around and between struts formed within the substrate. The struts may each be formed with a desired shape and orientation within the substrate to achieve a desired degree of fluid flow through the flow channels, in each of one of three dimensions, through the unit cell.

First claim

What is claimed is:

1. An engineered unit cell for flowing a fluid therethrough in three dimensions, the unit cell comprising:
a substrate;
a plurality of flow channels formed between and around a plurality of struts, the struts being disposed within the substrate; and
the struts each formed with a desired shape and orientation within the substrate such that the flow channels are configured to achieve a desired degree of fluid flow in each of three dimensions, through the unit cell; and wherein the unit cell forms a shape that can be tessellated so as to be configured with additional cells of the same shape into a contiguous structure.

2. The unit cell of claim 1 , wherein the struts comprise linear struts.

3. The unit cell of claim 1 , wherein the struts are dimensioned to cause the flow channels to create a capillary flow action when a fluid is exposed to at least one of the flow channels.

4. The unit cell of claim 1 , wherein the struts all intersect within the substrate.

5. The unit cell of claim 1 , wherein the struts extend non-parallel to one another.

6. An engineered, open channel, multi-cell structure for flowing a fluid therethrough in three dimensions, the structure comprising:
a plurality of unit cells formed adjacent to one another;
the unit cells having a shape enabling the unit cells to be tessellated to form a three-dimensional configuration of contiguous ones of the unit cells;
each of the unit cells having flow channels around at least one strut, wherein the strut extends through the unit cell, and the strut being in communication with a strut of at least one other one of the unit cells; and
the struts each formed with a desired shape and orientation within the structure such that the struts are configured to cause the flow channels achieve a desired degree of fluid flow in each of three dimensions, through the structure.

7. The structure of claim 6 , wherein each of the unit cells include a plurality of struts.

8. The structure of claim 7 , wherein the plurality of struts of a given one of the unit cells intersect at least at one point within the given one of the unit cells.

9. The structure of claim 6 , wherein the plurality of struts form a plurality of linear struts.

10. The structure of claim 7 , wherein the plurality of struts of different ones of the unit cells have different cross-sectional dimensions.

11. The structure of claim 7 , wherein the unit cells each comprise square shaped unit cells, and wherein each said unit cell comprises a plurality of four struts, each one of the four struts spanning between two corner points of the unit cell.

12. The structure of claim 11 , wherein the plurality of four struts intersect at a geometric center of the unit cell.

13. A method for forming an open wall, engineered structure for flowing a fluid therethrough in three dimensions, in a controlled manner, the method comprising:
forming a plurality of unit cells in an engineered, contiguous pattern using a material, the unit cells further being formed with a shape enabling the unit cells to be tessellated to form the engineered structure with substantially no gaps or voids between adjacent ones of the unit cells;
further forming the plurality of unit cells with a plurality of struts extending through the material, wherein areas around and between the struts form flow channels within the material; and
further forming each of the struts to extend fully through the unit cell.

14. The method of claim 13 , wherein further forming the plurality of unit cells with a plurality of struts comprises forming each of the unit cells with a plurality of linear struts.

15. The method of claim 14 , further comprising forming each of the linear struts such that the linear struts within a given one of the unit cells extend non-parallel to one another.

16. The method of claim 13 , further comprising forming the unit cells as cubic square shaped unit cells.

17. The method of claim 16 , further comprising forming each of the struts as linear struts.

18. The method of claim 17 , further comprising forming each one of the plurality of struts such that each communicates with two opposing corners of its associated said square shaped unit cell.

19. The method of claim 13 , further comprising forming the plurality of struts such that the plurality of struts all intersect one another at a geometric center of their associated said unit cell.

Assignees

• L Livermore Nat Security Llc

Inventors

• Deotte Joshua R
• Baker Sarah
• Duoss Eric
• Knipe Jennifer Marie
• Qian Fang
• Ruelas Samantha

Classifications

• B01L3/502707

  characterised by the manufacture of the container or its components · CPC title

• B01L3/502746 Primary

  characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves · CPC title

• B01L2300/161

  Control and use of surface tension forces, e.g. hydrophobic, hydrophilic · CPC title

• B01L2300/0874

  Three dimensional network · CPC title

• C12M33/00

  Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus (chemical or physical laboratory apparatus in general B01L, devices for taking cell samples A61B10/0045, withdrawing or distributing predetermined quantities of fluid B01L99/00) · CPC title