Bioreactor bags

Patent metadata

Field	Value
Publication number	US-11118149-B2
Application number	US-201916394601-A
Country	US
Kind code	B2
Filing date	Apr 25, 2019
Priority date	Apr 25, 2018
Publication date	Sep 14, 2021
Grant date	Sep 14, 2021

Abstract

Bioreactor bags formed from sheet materials are disclosed. The bioreactor bags include an opening which is openable and recloseable in a fluid tight manner for providing an opening for insertion of solid materials into the bag.

First claim

The invention claimed is:

1. A bioreactor bag formed from sheet materials,
wherein the sheet materials define a heat-sealed seam at a periphery of the bioreactor bag,
wherein the bioreactor bag defines a projecting lip comprising a recloseable section defining a resealable fluid-tight opening at the periphery of the bag into the bag configured to allow insertion of a solid material into the bag,
wherein the seam extends in opposing directions from opposing ends of the recloseable section along the periphery of the bag on a same side of the bag as the recloseable section,
wherein the projecting lip comprises a first panel and a second panel, wherein the first panel comprises a first portion, and wherein the second panel comprises a second portion resealable with the first portion, and
wherein the lip extends in a direction transverse to the seam.

2. The bioreactor bag of claim 1 , wherein the sheet materials comprise two sheets sealed together to form the seam at the periphery of the bag.

3. The bioreactor bag of claim 2 , wherein the periphery of the bag defines a polygon.

4. The bioreactor bag of claim 3 , wherein the opening is disposed at a side of the polygon.

5. The bioreactor bag of claim 4 , wherein the projecting lip defines the opening.

6. The bioreactor bag of claim 3 , wherein the polygon is a rectangle.

7. The bioreactor bag of claim 1 , wherein the first portion of the first panel defines a projecting rib extending along the lip, and wherein the second portion of the second panel defines a receiving channel extending along the lip, wherein the projecting rib is configured to resealably engage with the receiving channel.

8. The bioreactor bag of claim 7 , wherein the lip further comprises a sliding closure configured to slide along the projecting rib and receiving channel.

9. The bioreactor bag of claim 6 , wherein one or both of the first portion or the second portion comprises a fluid-tight resealable adhesive layer.

10. The bioreactor bag of claim 7 , wherein one or both of the first portion or the second portion comprises a fluid-tight resealable adhesive layer.

11. The bioreactor bag of claim 1 , wherein the sheet materials comprise a flexible polymer.

12. The bioreactor bag of claim 1 , further comprising a clamp extending along the opening, and covering the opening.

13. The bioreactor bag of claim 12 , wherein the clamp defines a C-shaped transverse cross-section.

14. The bioreactor bag of claim 12 , further comprising an inner rod extending along an interior of the clamp, wherein the clamp and the inner rod mechanically restrict the opening.

15. The bioreactor bag of claim 14 , wherein the sheet materials adjacent the opening are secured between the clamp and the inner rod.

16. The bioreactor bag of claim 1 , further comprising a valve fluidically coupled to an interior of the bag.

17. The bioreactor bag of claim 1 , further comprising a feed/drain port fluidically coupled to an interior of the bag.

18. The bioreactor bag of claim 1 , further comprising a filter assembly fluidically coupled to an interior of the bag.

19. The bioreactor bag of claim 1 , further comprising a sample line fluidically coupled to an interior of the bag.

Assignees

• Global Life Sciences Solutions Usa Llc

Inventors

• Saukkonen Hanna-Leena
• Stankowski Ralph

Classifications

• B01F31/20

  Mixing the contents of independent containers, e.g. test tubes · CPC title

• C12M23/46

  Means for fastening · CPC title

• C12M23/28

  disposable or single use · CPC title

• C12M29/14

  Pressurized fluid · CPC title

• C12M27/16

  Vibrating; Shaking; Tilting · CPC title