Methods for fabrication of an electrode delivery system

Patent metadata

Field	Value
Publication number	US-11117182-B2
Application number	US-201615776151-A
Country	US
Kind code	B2
Filing date	Nov 18, 2016
Priority date	Nov 18, 2015
Publication date	Sep 14, 2021
Grant date	Sep 14, 2021

Abstract

A method for fabricating electrodes sized and dimensioned to record, measure, and/or stimulate very fine nerve structures (e.g., microscale or less) is described herein. The method can include securing a tip of an electrode, comprising a conductor substantially encased by an insulator, to a proximal portion of an inserter. The electrode can be wound around a proximal portion of the inserter and a portion of the electrode can be secured to a distal portion of the inserter. A tension in the electrode can be maintained during the winding to keep the electrode in place during the winding.

First claim

The following is claimed:

1. A method comprising:
positioning an electrode in contact with an inserter, wherein the inserter is an elongated cylindrical shape including:
a proximal portion comprises a sharp tip configured to facilitate entrance of the inserter into tissue, and
a distal portion;

securing a tip of the electrode to the proximal portion of the inserter by a selective release mechanism, wherein the electrode comprises a conductor substantially encased by an insulator;
applying a tension to the electrode by an electrode holder;
winding the electrode around the proximal portion of the inserter by:
rotating the inserter to initiate the winding by a rotational motor, and
translating the electrode distally along the length of the inserter to produce at least two coils by a linear motor, wherein the tension is maintained during the winding to keep the electrode in place; and

securing a portion of the electrode to a distal portion of the inserter.

2. The method of claim 1 , wherein winding the electrode around the proximal portion of the inserter further comprises unwinding the electrode from a spool, wherein the distal end of the electrode is attached to a spool during the winding.

3. The method of claim 1 , wherein the sharp tip comprises a needle.

4. The method of claim 1 , further comprising releasing tension in the electrode after the portion of the electrode is secured to the distal portion of the inserter.

5. The method of claim 1 , wherein securing the distal portion of the electrode to the distal portion of the inserter further comprises securing the distal portion of the electrode to the distal portion of the inserter with an adhesive material or adhesive tape.

6. The method of claim 1 , wherein the conductor comprises a wire with a lateral size of 100 μm or less.

7. The method of claim 1 , wherein securing the distal portion of the electrode to the distal portion of the inserter further comprises securing the distal portion of the electrode to the distal portion of the inserter with a knot.

8. The method of claim 1 , wherein securing the tip of the electrode to the proximal portion of the inserter further comprises securing the tip of the electrode to the proximal portion of the inserter with a biodegradable substance.

9. The method of claim 8 , wherein the biodegradable substance comprises sucrose.

10. The method of claim 1 further comprising:
securing a tip of a second electrode to a distal portion of the proximal portion of the inserter by a second selective release mechanism;
applying a tension to the second electrode by the second electrode holder;
winding the second electrode around the inserter, wherein the tension is maintained during the winding to keep the second electrode in place during the winding by a second rotational motor and a second linear motor; and
securing a distal portion of the second electrode to a distal portion of the inserter by a holding mechanism.

11. The method of claim 10 , wherein winding the second electrode around the inserter further comprises winding the second electrode around the inserter at substantially the same time as winding the electrode around the inserter.

12. The method of claim 10 , wherein securing the distal portion of the second electrode to the distal portion of the inserter further comprises securing the second electrode to a same part of the distal portion of the inserter as the electrode, wherein both the electrode and the second electrode are both secured with at least one of adhesive tape or knots.

Assignees

• Univ Case Western Reserve

Inventors

• Durand Dominique

Classifications

• A61B5/6877

  Nerve · CPC title

• A61B5/6868

  Brain · CPC title

• A61B5/4029

  for evaluating the peripheral nervous systems (using bioelectric or biomagnetic signals A61B5/24) · CPC title

• A61N1/0551

  Spinal or peripheral nerve electrodes · CPC title

• A61B2562/125

  characterised by the manufacture of electrodes · CPC title