X-ray diagnostic apparatus and image processing apparatus

Patent metadata

Field	Value
Publication number	US-11116464-B2
Application number	US-201615331114-A
Country	US
Kind code	B2
Filing date	Oct 21, 2016
Priority date	Oct 28, 2015
Publication date	Sep 14, 2021
Grant date	Sep 14, 2021

Abstract

An X-ray diagnostic apparatus according to an embodiment includes processing circuitry configured to acquire a plurality of X-ray images over time based on X-rays having passed through a subject injected with a contrast agent, to calculate a blood vessel region corresponding to an inflow path of the contrast agent leading to a predetermined position in the blood vessel region, based on a temporal transition of signal intensities of the contrast agent in the blood vessel region represented in the X-ray images, and to perform control to display the blood vessel region corresponding to the inflow path in a display mode that is different from that of a blood vessel region other than the inflow path on a display.

First claim

What is claimed is:

1. An X-ray diagnostic apparatus, comprising:
processing circuitry configured to:
acquire a plurality of X-ray images over time based on X-rays having passed through a subject injected with a contrast agent;
calculate an inflow path from among a plurality of blood vessels representing possible inflow paths by performing searching using a temporal transition of signal intensities of the injected contrast agent along the inflow path in a direction opposite a direction of blood flow, wherein the inflow path is a first blood vessel region of a path in the X-ray images traversed by the injected contrast agent leading to a predetermined position in a second blood vessel region in the X-ray images; and
perform control to display, on a display, the calculated inflow path of the first blood vessel region in a display mode that is different from that of a blood vessel region other than the inflow path.

2. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry is further configured to:
calculate, for each unit area consisting of one or more pixels in the X-ray images, a feature quantity related to a flow of the injected contrast agent, based on the temporal transition of the signal intensities, and
calculate the inflow path based on continuity of the calculated feature quantity.

3. The X-ray diagnostic apparatus according to claim 2 , wherein the processing circuitry is further configured to:
use a unit area corresponding to the predetermined position as a starting point and sequentially compare feature quantities of adjacent unit areas, starting from the unit area corresponding to the starting point, and
sequentially identify a unit area with a feature quantity that is temporarily previous, and calculate identified unit areas as the inflow path.

4. The X-ray diagnostic apparatus according to claim 2 , wherein, when a third blood vessel region represented in the X-ray images has an intersecting portion in which blood vessels intersect with each other, the processing circuitry is further configured to
calculate, for each unit area near the intersecting portion, an evaluation that is based on continuity of the feature quantity at the unit area and the feature quantity at a unit area immediately previous to the intersecting portion, and a positional relation between the unit area and the unit area immediately previous to the intersecting portion, and
calculate the inflow path through the intersecting portion based on the calculated evaluation.

5. The X-ray diagnostic apparatus according to claim 4 , wherein the processing circuitry is further configured to calculate the evaluation based on a direction of the inflow path to the unit area immediately previous to the intersecting portion.

6. The X-ray diagnostic apparatus according to claim 4 , wherein the processing circuitry is further configured to
calculate a plurality of feature quantities,
calculate the evaluation based on the calculated feature quantities, and
calculate the inflow path through the intersecting portion based on the calculated evaluation.

7. The X-ray diagnostic apparatus according to claim 4 , wherein, when a difference between evaluations of respective unit areas near the intersecting portion is less than a predetermined threshold, the processing circuitry is further configured to determine a plurality of blood vessel regions corresponding to the inflow path, the blood vessel regions including the respective unit areas each having the evaluation.

8. The X-ray diagnostic apparatus according to claim 7 , wherein the processing circuitry is further configured to receive an operation of selecting one of the calculated blood vessel regions corresponding to the inflow path.

9. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry is further configured to calculate the inflow path through an intersecting portion in which blood vessels intersect with each other in the X-ray images acquired from a predetermined direction, by comparing the X-ray images with another plurality of X-ray images acquired from a direction that is different from the predetermined position.

10. The X-ray diagnostic apparatus according to claim 1 , wherein, when a third blood vessel region in the X-ray images has an intersecting portion in which blood vessels intersect with each other, the processing circuitry is further configured to calculate a vector representing a movement of the injected contrast agent, for each unit area consisting of one or more pixels, in the third blood vessel region in the X-ray images, near the intersecting portion, by comparing the X-ray images with each other, and calculate the inflow path through the intersecting portion based on a similarity of the vectors in the respective unit areas.

11. The X-ray diagnostic apparatus according to claim 1 , wherein, when the second blood vessel region in the X-ray images has an intersecting portion in which blood vessels intersect with each other, the processing circuitry is further configured to calculate the inflow path through the intersecting portion by performing computational fluid dynamics based on the X-ray images.

12. The X-ray diagnostic apparatus according to claim 1 , wherein, when the second blood vessel region in the X-ray images has an intersecting portion in which blood vessels intersect with each other, the processing circuitry is further configured to calculate the inflow path through the intersecting portion based on similarity in the temporal transitions of the signal intensities of the injected contrast agent at respective unit areas each of which consists of one or more pixels, in the second blood vessel region in the X-ray images.

13. The X-ray diagnostic apparatus according to claim 2 , wherein the feature quantity calculated by the processing circuitry is time required for the signal intensities to reach a peak from a predetermined timing, a peak signal intensity, or a cumulative sum of the signal intensities.

14. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry is further configured to perform control to display the inflow path as a blood vessel image in a roadmap on the display, or display the X-ray images in which the inflow path is emphasized as a blood vessel image in the roadmap on the display.

15. The X-ray diagnostic apparatus according to claim 2 , wherein the processing circuitry is further configured to:
generate a color image, each unit area of which is reflected with color information that is based on the feature quantity, and
perform control to display the first blood vessel region corresponding to the calculated inflow path in the color image, as a blood vessel image in a roadmap, on the display.

16. The X-ray diagnostic apparatus according to claim 15 , wherein the processing circuitry is further configured to perform control to display the first blood vessel region corresponding to the calculated inflow path in the color image, and the second blood vessel region in the X-ray image, as the blood vessel image in the roadmap, on the display.

17. The X-ray diagnostic apparatus according to claim 1 , wherein the processing circuitry is further configured to:
receive a designation of the predetermined position in a color image in which each unit area consisting of one or more pixels in blood vessel regions represented in the X-ray images is reflected with color information that is based on the X-ray images or based on a feature quantity calculated based on the temporal transition of the signal intensity of the injected cont

Assignees

• Toshiba Medical Sys Corp
• Canon Medical Systems Corp

Inventors

• TAKAYA Mika
• Abe Shingo
• Fuchigami Ko
• Nagae Ryoichi
• Sakaguchi Takuya

Classifications

• A61B6/5211

  involving processing of medical diagnostic data · CPC title

• A61B6/12

  Arrangements for detecting or locating foreign bodies · CPC title

• A61B6/487

  involving fluoroscopy · CPC title

• A61B6/481

  involving the use of contrast agents · CPC title

• A61B6/507

  for determination of haemodynamic parameters, e.g. perfusion CT · CPC title