Mutant pore

US11104709B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11104709-B2
Application numberUS-201716091746-A
CountryUS
Kind codeB2
Filing dateApr 6, 2017
Priority dateApr 6, 2016
Publication dateAug 31, 2021
Grant dateAug 31, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using the mutant forms of lysenin.

First claim

Opening claim text (preview).

The invention claimed is: 1. A mutant lysenin monomer comprising a variant of the amino acid sequence set forth in SEQ ID NO: 2, wherein the variant comprises one of the following combinations of amino acid substitutions: E94D/K99Q/T106K; E94D/T93K/T106K; E94D/T91K/T106K; H83K/E94D/T106K; E94Q/Y96D/T106K; K45D/E94K/T106K; K45R/E94D/T106K; E94D/S98K/K99L/T106K; K37N/E94D/T106K; K37W/E94D/T106K; K37S/E94D/T106K; K45N/E94N/T106K; K37Q/E94D/E102N/T106K; K37S/E94D/E102S/T106K; K37S/E94D/T104K/T106K; K45Q/E94Q/T106K; K45T/V47K/E94D/T106K; V47S/E94D/T106K; T51K/E94D/T106K; K45Y/S49K/E94D/T106K; S49L/E94D/T106K; K45R/T106K; V47K/E94D/T106K; G43K/E94D/T106K; V88I/M90A/E94D/T106K; V47N/V88T/E94D/T106K; K45N/S49K/E94N/E92D/T106K; K45N/V47K/E92D/E94N/T106K; or E94D/K99Q/T106K.

Assignees

Inventors

Classifications

  • from invertebrates · CPC title

  • C12Q1/6869Primary

    Methods for sequencing · CPC title

  • electrical properties of nucleic acids, e.g. impedance, conductivity or resistance · CPC title

  • involving nucleic acids · CPC title

  • from worms · CPC title

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Frequently asked questions

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What does patent US11104709B2 cover?
The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using the mutant forms of lysenin.
Who is the assignee on this patent?
Oxford Nanopore Tech Ltd
What technology area does this patent fall under?
Primary CPC classification C12Q1/6869. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 31 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).