Glass packaging ensuring container integrity

Patent metadata

Field	Value
Publication number	US-11091392-B2
Application number	US-201715814917-A
Country	US
Kind code	B2
Filing date	Nov 16, 2017
Priority date	Feb 29, 2012
Publication date	Aug 17, 2021
Grant date	Aug 17, 2021

Abstract

A strengthened glass container or vessel such as, but not limited to, vials for holding pharmaceutical products or vaccines in a hermetic and/or sterile state. The strengthened glass container undergoes a strengthening process that produces compression at the surface and tension within the container wall. The strengthening process is designed such that the tension within the wall is great enough to ensure catastrophic failure of the container, thus rendering the product unusable, should sterility be compromised by a through-wall crack. The tension is greater than a threshold central tension, above which catastrophic failure of the container is guaranteed, thus eliminating any potential for violation of pharmaceutical integrity.

First claim

The invention claimed is:

1. A method of making an aluminosilicate glass article having a first surface and a second surface separated by a thickness, the method comprising:
forming a first region in at least one surface of the glass by ion-exchanging the glass, wherein the first region extends from at least one of the first surface or the second surface to a depth of layer in the glass, and wherein the first region is under a compressive stress and the thickness is from 0.9 mm to 1.2 mm; and
forming a second region under a central tension of at least 15 MPa, the second region extending from the depth of layer, wherein the central tension is sufficient to allow self-propagation of a crack front from the first surface to the second surface and laterally across at least the first surface;
wherein the glass article is a container adapted to hold a pharmaceutical product, a vaccine, a biologic, a foodstuff, or a solution.

2. The method of claim 1 , wherein the self-propagation of the crack front from the first surface to the second surface and laterally across at least the first surface renders the glass article unsuitable for its intended use.

3. The method of claim 1 , wherein the self-propagation of the crack front from the first surface to the second surface further comprises bifurcation of the crack front across at least the first surface.

4. The method of claim 1 , wherein the glass has a Young's modulus E and a Poisson's ratio ν, and (CT 2 /E)·(t−2DOL)·(1−ν)≥3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer.

5. The method of claim 4 , wherein (CT 2 /E)·(t−2DOL)·(1−ν)≥9.5 MPa·μm.

6. The method of claim 4 , wherein (CT 2 /E)·(t−2DOL)·(1−ν)≥15.0 MPa·μm.

7. The method of claim 1 , wherein the central tension is greater than or equal to 30 MPa.

8. The method of claim 7 , wherein the central tension is greater than or equal to 45 MPa.

9. The method of claim 1 , wherein the compressive stress is at least 200 MPa.

10. The method of claim 1 , wherein the depth of layer is at least 30 μM.

11. The method of claim 1 , wherein the depth of layer is in a range from 15% to 25% of the thickness.

12. The method of claim 1 , wherein the thickness is up to 6 mm.

13. The method of claim 12 , wherein the thickness is in a range from 0.3 mm to 2.0 mm.

14. A method of making a glass article comprising a glass and wherein the glass article has a first surface and a second surface separated by a thickness, the method comprising:
forming a first region of the glass article, wherein forming the first region comprises applying a coating to at least one surface of the glass of the glass article, wherein the coating has a Young's modulus greater than the glass, wherein the first region extends from at least one of the first surface or the second surface to a depth of layer of the glass article, and wherein the first region comprises the coating and is under a compressive stress; and
forming a second region under a central tension of at least 15 MPa, the second region extending from the depth of layer, wherein the central tension is sufficient to allow self-propagation of a crack front from the first surface to the second surface and laterally across at least the first surface.

15. The method of claim 14 , the glass has a Young's modulus E and a Poisson's ratio ν, and (CT 2 /E)·(t−2DOL)·(1−ν)≥3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer.

16. The method of claim 14 , wherein the glass article is a container is adapted to hold a pharmaceutical product, a vaccine, a biologic, a foodstuff, or a solution.

17. A method of ensuring self-elimination of a vessel having an intended use, the method comprising:
providing the vessel, the vessel comprising an ion-exchanged aluminosilicate glass, the vessel having a thickness of from 0.9 mm to 1.2 mm and a first surface and a second surface, wherein the glass has a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension of at least 15 MPa, the second region extending from the depth of layer, wherein the glass has a Young's modulus E and a Poisson's ratio ν, and (CT 2 /E)·(t−2DOL)·(1−ν)≥3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer, wherein the central tension is greater than a threshold tensile stress that is sufficient to allow self-propagation of a crack front through the thickness from the first surface to the second surface, and wherein the self-propagation of the crack front from the first surface to the second surface renders the vessel unsuitable for its intended use.

18. The method of claim 17 , wherein the self-propagation of the crack front from the first surface to the second surface further comprises bifurcation of the crack front across at least the first surface.

Assignees

• Corning Inc

Inventors

• Demartino Steven Edward
• Schaut Robert Anthony

Classifications

• C03C21/002 Primary

  to perform ion-exchange between alkali ions (C03C21/005 takes precedence) · CPC title

• B32B17/06

  comprising glass as the main or only constituent of a layer, next to another layer of a specific {material} · CPC title

• C03C21/00 Primary

  Treatment of glass, not in the form of fibres or filaments, by diffusing ions or metals in the surface · CPC title

• B65D13/02

  of glass, pottery, or other ceramic material · CPC title

• C03B9/31

  Blowing laminated glass articles or glass with enclosures, e.g. wires, bubbles · CPC title