Sub-nanosecond laser surgery system utilizing multiple pulsed laser beams

Patent metadata

Field	Value
Publication number	US-11083625-B2
Application number	US-201615183658-A
Country	US
Kind code	B2
Filing date	Jun 15, 2016
Priority date	Jul 1, 2015
Publication date	Aug 10, 2021
Grant date	Aug 10, 2021

Abstract

A system for laser ophthalmic surgery includes: a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam. The first treatment laser beam has a pulse energy of 10 to 500 μJ. The second pulsed laser beam has a second pulse energy of about 0.1 to 10 μJ, lower than the first treatment laser beam. An optical system focuses the first treatment laser beam to a first focal spot and directs the first focal spot in a first treatment pattern into a first intraocular target. The optical system also focuses the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into a second intraocular target. The first intraocular target and second intraocular target are different.

First claim

What is claimed is:

1. A system for laser ophthalmic surgery on an eye of a patient, comprising:
a single laser source, under the operative control of a controller, configured to alternatively deliver a first treatment laser beam and a second treatment laser beam, each treatment laser beam comprising a plurality of laser pulses, the first treatment laser beam having a first wavelength and the second treatment laser beam having a second wavelength which is shorter than the first wavelength, wherein the first treatment laser beam is either a first harmonic which is an infrared wavelength of between 870 nm and 1200 nm, or a second harmonic which is a visible wavelength of between 475 nm and 600 nm, and the second treatment laser beam is a third harmonic which is an ultraviolet wavelength of between 320 nm and 370 nm; and
an optical system operatively coupled to the laser source by the controller and configured to focus the first treatment laser beam to a first focal spot and direct the first focal spot in a first treatment pattern into one or more intraocular targets including a first intraocular target,
the optical system being further configured to focus the second treatment laser beam to a second focal spot and direct the second focal spot in a second treatment pattern into the one or more intraocular targets including a second intraocular target,
wherein the optical system includes a first optical path section, a second optical path section separate from the first optical path section, a beam splitting optical element configured to direct the first treatment laser beam along the first optical path section and direct the second treatment laser beam along the second optical path section, and a beam combining optical element configured to combine the first treatment laser beam on the first optical path section and the second treatment laser beam on the second optical path section into a common optical path section, wherein the first optical path section includes a first confocal imaging assembly which is optimized to detect back reflected light from the eye having the first wavelength, the second optical path section includes a second confocal imaging assembly which is separate from the first confocal imaging assembly and which is optimized to detect back reflected light from the eye having the second wavelength.

2. The system of claim 1 , wherein a repetition rate of the first treatment laser beam is about 1 to 50 KHz and wherein the second treatment laser beam has a repetition rate of about 50 to 200 KHz and is higher than that of the first treatment laser beam of between.

3. The system of claim 1 , wherein a pulse duration of the first treatment laser beams is less than 1 nanosecond and a pulse duration of the second treatment laser beam is less than 1 nanosecond.

4. The system of claim 1 , wherein a pulse duration of first treatment laser beam is about 1 ps and 150 ps, and a pulse duration of the second treatment laser beam is about 1 ps and 150 ps.

5. The system of claim 1 , wherein the laser source is configured to alternatively deliver a first probe laser beam corresponding to the first treatment laser beam and a second probe laser beam corresponding to the second treatment laser beam; and
wherein the optical system is configured to direct the first probe laser beam to the one or more intraocular targets and to direct back reflected light of the first probe laser beam from the one or more intraocular targets to the first confocal imaging assembly, thereby obtaining first image data corresponding to a first area of the one or more intraocular targets,
wherein the optical system is further configured to direct the second probe laser beam to the one or more intraocular targets and to direct back reflected light of the second probe laser beam from the one or more intraocular targets to the second confocal imaging assembly, thereby obtaining second image data corresponding to a second area of the one or more intraocular targets,
wherein the first area is different from the second area.

6. The system of claim 5 , wherein the first area comprises one or more portions of ophthalmic tissue selected from the group consisting of a crystalline lens, a posterior portion of the lens capsule, and a posterior pole of the eye.

7. The system of claim 6 , wherein the first area is at least a portion of the crystalline lens, the first image data corresponds to image data of the crystalline lens, the first treatment pattern is a lens fragmentation treatment pattern, and the lens fragmentation treatment pattern is determined based at least in part on the image data of the crystalline lens.

8. The system of claim 5 , wherein the second area is one or more portions of ophthalmic tissue selected from the group consisting of a cornea and an anterior lens capsule.

9. The system of claim 1 , wherein the first laser beam has pulse energy of between 10 and 500 μJ and the second laser beam has pulse energy of between 0.1 and 10 μJ.

10. The system of claim 1 , wherein the first intraocular target is one or more selected from the group consisting of the crystalline lens and the posterior portion of the lens capsule and the second intraocular target is one or more selected from the group consisting of a cornea and an anterior lens capsule.

11. The system of claim 1 , wherein the first intraocular target is a crystalline lens and the first treatment pattern is a lens fragmentation pattern treatment pattern.

12. The system of claim 1 , wherein the second intraocular target is a cornea and the second treatment pattern is selected from the group consisting of an arcuate incision treatment pattern, a primary cataract incision treatment pattern and a sideport incision treatment pattern.

13. The system of claim 1 , wherein the second intraocular target is an anterior lens capsule and the second treatment pattern is a capsulotomy treatment pattern.

14. The system of claim 1 , wherein the first treatment laser beam is a first harmonic.

15. A system for laser ophthalmic surgery on an eye of a patient, comprising:
a single laser source, under the operative control of a controller, configured to alternatively deliver a first laser beam and a second laser beam, each laser beam comprising a plurality of laser pulses, the first laser beam having a first wavelength and the second laser beam having a second wavelength which is shorter than the first wavelength, wherein the first laser beam is either a first harmonic which is an infrared wavelength of between 870 nm and 1200 nm, or a second harmonic which is a visible wavelength of between 475 nm and 600 nm, and the second laser beam is a third harmonic which is an ultraviolet wavelength of between 320 nm and 370 nm; and
an optical system operatively coupled to the laser source by the controller and configured to focus the first laser beam to a first focal spot and direct the first focal spot in a first pattern into a first portion of the eye located more than a predefined distance from an anterior surface of a cornea of the eye,
the optical system being further configured to focus the second laser beam to a second focal spot and direct the second focal spot in a second pattern into a second portion of the eye located less than the predefined distance from the anterior surface of the cornea,
wherein the optical system includes a first optical path section, a second optical path section separate from the first optical path section, a beam splitting optical element configured to direct the first laser beam along the first optical path section and direct the second laser beam along the second optical path section, and a bea

Assignees

• Optimedica Corp
• Amo Dev Llc

Inventors

• Schuele Georg
• Andersen Dan
• Vankov Alexander
• Gooding Phillip H

Classifications

• A61F9/00825 Primary

  for photodisruption · CPC title

• A61F2009/00889

  Capsulotomy · CPC title

• A61F2009/00887

  Cataract · CPC title

• A61F2009/0087

  Lens · CPC title

• A61F2009/00897

  Scanning mechanisms or algorithms · CPC title