Fluid dispensing device with a flow detector

Patent metadata

Field	Value
Publication number	US-11077244-B2
Application number	US-201816151785-A
Country	US
Kind code	B2
Filing date	Oct 4, 2018
Priority date	Nov 1, 2010
Publication date	Aug 3, 2021
Grant date	Aug 3, 2021

Abstract

A portable therapeutic fluid delivery device with a flow detector comprising a heating element and two temperature sensors is presented. Upon activation of the heating element, a flow condition of the fluid inside the delivery tube is determined based on a signal provided by the temperature sensors. A temperature gradient within the therapeutic fluid is detected. The determined flow condition can be one of: air bubbles within the delivery tube, occlusion within the delivery tube, or leakage within the delivery tube. The device can have two parts, for example, a reusable part and a disposable part. Upon pairing of these parts, the heating element and the temperature sensors touch the delivery tube.

First claim

The invention claimed is:

1. A portable therapeutic fluid delivery device for delivering a therapeutic fluid into a body of a patient, the fluid delivery device comprising:
a first part which comprises:
a driving mechanism,
a processor,
a flow detector comprising two electronic components electrically coupled to the processor; and

a second part which comprises:
a reservoir,
an exit port, and
a delivery tube communicating between the reservoir and the exit port,

wherein the first part and the second part are designed such that upon pairing of the first part with the second part, the two electronic components of the flow detector are thermally coupled to the delivery tube, and upon activation of a first one of the two electronic component to heat the delivery tube, the processor is configured to determine flow condition of the therapeutic fluid inside the delivery tube based on sensed temperature provided to the processor by a second one of the two electronic components.

2. The fluid delivery device according claim 1 , wherein the delivery device adjusts or controls delivery of the therapeutic fluid through the delivery tube based, at least in part, on a determined flow rate such that the therapeutic fluid is delivered at a pre-determined delivery rate.

3. The fluid delivery device according claim 1 , further comprising a motor, wherein the processor controls the motor to keep delivery of the therapeutic fluid through the delivery tube at a pre-determined delivery rate.

4. The fluid delivery device according claim 1 , further comprising a motor, wherein the processor controls the motor to keep delivery of the therapeutic fluid through the delivery tube at a pre-determined delivery rate based, at least in part, on a determined flow rate.

5. The fluid delivery device according claim 1 , wherein the first one of the two electronic components is a heating element and the second one of the two electronic components is a temperature sensor.

6. The fluid delivery device according claim 1 , wherein the second one of the two electronic components is a temperature sensor selected from a temperature-sensitive resistor, a thermistor, and a silistor.

7. The fluid delivery device according to claim 1 , wherein the flow condition includes at least one of: air bubbles within the delivery tube, an occlusion within the delivery tube, a leakage within the delivery tube, or combinations thereof.

8. The fluid delivery device according to claim 1 , wherein the fluid delivery device alerts the patient to conditions of occlusion, air bubbles, leakage in the delivery tube or combinations thereof.

9. The fluid delivery device according to claim 1 , wherein the fluid delivery device is remotely controlled.

10. The fluid delivery device according to claim 1 , wherein the fluid delivery device comprises a skin securable drug dispensing unit, the drug dispensing unit comprises the first part and the second part.

11. The fluid delivery device according to claim 1 , wherein the fluid delivery device comprises a blood glucose sensing apparatus.

12. The fluid delivery device according to claim 1 , wherein the fluid delivery device comprises a skin securable drug dispensing unit comprising buttons, and wherein the drug dispensing unit is operated manually using the buttons.

13. The fluid delivery device according to claim 1 , wherein the fluid delivery device disconnects from and reconnects to a skin adherable cradle unit.

14. The fluid delivery device according to claim 1 , wherein the first part or the second part comprises an energy supply.

15. The fluid delivery device according to claim 1 , further comprising a handheld remote control unit which comprises an integrated blood glucose monitor.

16. The fluid delivery device according to claim 1 , further comprising a subcutaneous insertable tip, wherein the subcutaneous insertable tip serves both as a therapeutic fluid cannula and a sensing probe.

17. The fluid delivery device according to claim 1 , wherein the driving mechanism comprises a motor.

18. The fluid delivery device according to claim 17 , further comprising a pulse generator coupled to the motor to operate the motor, wherein the fluid delivery device detects an occlusion by detecting a mismatch between pulses supplied to the motor and motor operation.

19. The fluid delivery device according to claim 17 , wherein the fluid delivery device is configured to deliver power to the first one of the two electronic components, suspend power delivery to the first one of the two electronic components, and deliver power to the motor to begin motor operation subsequent to the suspension of power delivery to the first one of the two electronic components.

20. The fluid delivery device according to claim 17 , further comprising a capacitor and a power supply, wherein the fluid delivery device is configured to periodically charge the capacitor via the power supply and periodically discharge the capacitor by operating the motor.

21. The fluid delivery device according to claim 20 , wherein the fluid delivery device is configured to periodically discharge the capacitor by powering the first one of the two electronic components.

22. The fluid delivery device according to claim 1 , further comprising a revolution counter and a motor operably controlled by the processor, wherein the processor provides pulses to the motor to power the motor, and wherein the fluid delivery device detects an occlusion if the flow detector determines a condition of no flow in the delivery tube and there is a mismatch between pulses generated by the processor and a predicted number of motor revolutions from the revolution counter.

23. The fluid delivery device according to claim 1 , wherein the delivery tube is elastic or flexible.

24. The fluid delivery device according to claim 1 , wherein the delivery device, in response to a determination that there is no fluid flow, is configured to identify one or more of several possible problems causing a condition of no fluid flow, the several possible problems comprise a missing pulse of motor operation, the reservoir of the therapeutic fluid being empty, presence of air bubbles n the delivery tube, occlusion occurring in the delivery tube and combinations thereof.

Assignees

• Roche Diabetes Care Inc

Inventors

• Neta Avraham
• Tsypko Konstantin
• Tsypko Nikolay
• Yodfat Ofer

Classifications

• A61M5/14248 Primary

  of the skin patch type · CPC title

• A61M2205/3368

  Temperature · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title

• A61M5/14244 Primary

  adapted to be carried by the patient, e.g. portable on the body · CPC title

• A61M5/365

  Air detectors (A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626) · CPC title