Anastomosis device

Patent metadata

Field	Value
Publication number	US-11076856-B2
Application number	US-201716303188-A
Country	US
Kind code	B2
Filing date	May 23, 2017
Priority date	May 23, 2016
Publication date	Aug 3, 2021
Grant date	Aug 3, 2021

Abstract

According to some embodiments there is provided an anastomosis device configured to reduce leakage, comprising: a first set of rings sized to be positioned at a first tissue wall; a second set of rings sized to be positioned at a second tissue wall adjacent the first tissue wall; and an element configured to draw the ring sets towards each other; wherein each set of rings comprises an inner ring, an outer ring, and a coupling for aligning the inner and outer rings with respect to each other; wherein the inner ring applies a first pressure onto the tissue wall which is sufficient to gradually form a passage between the first and second tissue walls; and the outer ring applies a second pressure onto the tissue wall, the second pressure applied radially outwardly relative to the first pressure, the second pressure sufficient to reduce leakage in a vicinity of the passage.

First claim

What is claimed is:

1. An anastomosis device configured to reduce leakage, comprising:
a first set of rings sized to be positioned at a first tissue wall;
a second set of rings sized to be positioned at a second tissue wall, the second tissue wall being adjacent the first tissue wall; and
drawing means for approximating the ring sets towards each other;
wherein each set of rings comprises:
an inner ring having a tissue-facing surface;
an outer ring having a tissue-facing surface; and
a coupling between the inner ring and the outer ring for aligning the inner and outer rings with respect to each other; the inner ring and the outer ring being co-axial, the outer ring circumferentially surrounding the inner ring;

wherein when the device is deployed in tissue and the rings sets are approximated towards each other by the drawing means:
tissue-facing surfaces of the inner rings overlap to compress tissue in-between, and tissue-facing surfaces of the outer rings overlap;
the inner rings apply a first pressure between them onto the first and second tissue walls, the first pressure sufficient to gradually form a passage between the first and second tissue walls; and
the outer rings apply a second pressure between them onto the first and second tissue walls, the second pressure applied radially outwardly relative to the first pressure, the second pressure sufficient to reduce leakage in a vicinity of the passage.

2. The device according to claim 1 , wherein one or both of the inner ring and the outer ring of each set is inflatable.

3. The device according to claim 2 , wherein pressure applied by the inner ring and the outer rings onto the tissue is controlled by inflation pressures.

4. The device according to claim 1 , wherein the drawing means comprise an inner construction incorporated in each of the ring sets.

5. The device according to claim 4 , wherein the inner construction comprises magnetic material incorporated in or mounted on one or both of the inner ring and the outer rings of each set, the magnetic material positioned to induce magnetic attraction between the inner rings of the two sets and/or between the outer rings of the two sets.

6. The device according to claim 4 , wherein the inner construction comprises shape memory material incorporated in one or both of the inner ring and the outer rings of each set, the shape memory material shaped and positioned so that deformation of the shape memory material changes a level of pressure applied by one or both of the inner ring and the outer rings onto the tissue.

7. The device according to claim 1 , wherein the drawing means comprise an elongated element which extends between the two sets of rings, interconnecting the two sets.

8. The device according to claim 7 , wherein the elongated element is one of: a string, wire or cable.

9. The device according to claim 7 , wherein the elongated element is tensioned to set at least an initial pulling force between the—inner rings of the two sets and/or between the outer rings of the two sets.

10. The device according to claim 1 , wherein the coupling between the inner ring and the outer ring comprises one or more bridging elements extending between the inner ring and the outer ring.

11. The device according to claim 1 , wherein the coupling between the inner ring and the outer ring comprises an adhesive attaching the at least a portion of an outer lining of the inner ring to at least a portion of an inner lining of the outer ring.

12. The device according to claim 1 , wherein the device comprises a leakage indicator comprising a temperature sensor or a PH meter.

13. The device according to claim 1 , wherein the device comprises one or more pressure sensors positioned at an interface between the tissue and one or both of the inner ring and the outer ring of each set, the pressure sensors configured to detect an actual pressure applied by the inner ring and/or the outer ring onto the tissue.

14. The device according to claim 1 , wherein the device comprises one or more sensors configured for detecting a level of oxygen saturation of the compressed tissue.

15. The device according to claim 1 , wherein the inner ring of each set further comprises a cutting wire.

16. The device according to claim 1 , wherein one or both of the inner ring and the outer ring of each set comprises a toroidal shaped balloon.

17. The device according to claim 1 , wherein a contact surface area of the outer ring with the tissue is larger than a contact surface area of the inner ring with the tissue.

18. The device according to claim 1 , wherein the drawing means comprise an interconnecting element configured to be tensioned and/or shortened to approximate the ring sets towards each other.

19. The device according to claim 1 , wherein the first pressure is sufficient to cut through tissue to gradually form the passage, and the second pressure is high enough to reduce leakage in a vicinity of the passage yet low enough to avoid ischemia and tissue necrosis.

20. The device according to claim 1 , wherein the tissue facing-surface of the inner ring of each set comprises a protrusion for applying increased pressure at a localized point.

21. The device according to claim 1 , wherein the drawing means are configured to exert a pulling force sufficient to produce the first pressure and the second pressure.

22. An anastomosis device configured to reduce leakage, comprising:
a set of two rings for positioning over adjacent first and second tissue walls, each ring comprising at least:
a first chamber configured to apply a first pressure onto a respective tissue wall out of the first and second tissue walls, the pressure sufficient to form a passage between the first and second tissue walls; and
a second chamber configured to apply a second pressure onto the respective tissue wall out of the first and second tissue walls, the pressure applied radially outwardly relative to the first pressure, the second pressure sufficient to reduce leakage in a vicinity of the passage.

23. The device according to claim 22 , wherein the chambers are inflatable.

24. The device according to claim 22 , wherein each ring out of the set of two rings further comprises a third chamber configured to apply a third pressure onto the respective tissue wall, the third pressure lower than the second pressure.

25. An anastomosis device configured to reduce leakage, comprising:
a first set of structures shaped and sized to be positioned at a first tissue wall;
a second set of structures shaped and sized to be positioned at a second tissue wall, the second tissue wall being adjacent the first tissue wall; and
an element configured to draw the sets towards each other;
wherein each set of structures comprises an inner substantially closed shape, an outer substantially closed shape surrounding the inner shape, and a coupling element between the inner substantially closed shape and the outer substantially closed shapes, the coupling element configured to control a ratio between a first pressure applied by the inner substantially closed shape onto the tissue, and a second pressure applied by the outer substantially closed shape onto the tissue.

Assignees

• Mor Research Applic Ltd

Inventors

• Kopelman Doron

Classifications

• A61B17/11 Primary

  for performing anastomosis; Buttons for anastomosis · CPC title

• A61B17/1227

  Spring clips · CPC title

• A61B17/32053

  Punch like cutting instruments, e.g. using a cylindrical or oval knife (A61B17/326 takes precedence; trepans A61B17/1695) · CPC title

• A61B17/083

  Clips, e.g. resilient · CPC title

• A61B2017/1139

  Side-to-side connections, e.g. shunt or X-connections · CPC title