Body temperature measurement devices, methods, and systems

Patent metadata

Field	Value
Publication number	US-11071814-B2
Application number	US-201916387744-A
Country	US
Kind code	B2
Filing date	Apr 18, 2019
Priority date	Oct 9, 2015
Publication date	Jul 27, 2021
Grant date	Jul 27, 2021

Abstract

A core temperature measurement may be made by varying the heat transfer dynamics of a blood circuit and fitting parameters of a blood circuit heat transfer configuration to measurements under the varied conditions. Then the input temperature of the patient core can be extracted from the model and a current temperature measurement remote from the patient core and optionally other measurements such as blood flow rate.

First claim

The invention claimed is:

1. A blood treatment system, comprising:
a blood pump and a temperature sensor, the blood pump and temperature sensor being configured to receive a predefined fluid circuit having a blood circuit with a blood inlet;
a controller connected to the blood pump to control a speed thereof and to the temperature sensor to receive a temperature signal output therefrom;
the temperature sensor being configured to detect a temperature of blood carried by the blood circuit;
the controller being programmed to operate the pump at at least two flow rates, record first and second temperature data responsive to the temperature signal at each flow rate, respectively and to calculate an inlet temperature at said blood inlet, responsive to both the first and second temperature data, where the inlet temperature is an estimation of the temperature at a point in said blood circuit remote from the temperature sensor and compensates for a temperature change in flowing blood between said point and said temperature sensor.

2. The system of claim 1 , wherein the controller is connected to a user interface with a display and is further programmed to show said inlet temperature on said display.

3. The system of claim 1 , further comprising a treatment fluid pump connected for control by said controller, the treatment fluid pump engaging a treatment fluid circuit of said predefined fluid circuit; wherein the controller is further programmed to operate said blood pump at said at least two flow rates during a temperature measurement phase of a startup mode of said blood treatment system.

4. The system of claim 3 , wherein in the temperature measurement phase of the startup mode the controller controls the treatment fluid pump to prevent flow in the treatment fluid circuit.

5. The system of claim 4 , wherein the predefined fluid circuit has a treatment device that forms a heat transfer interface between the treatment fluid circuit and the blood circuit such that heat is transferred between the blood in the blood circuit and treatment fluid in the treatment fluid circuit.

6. The system of claim 5 , further comprising a temperature regulator that engages the treatment fluid circuit, wherein the controller controls the temperature regulator to bring a treatment fluid to a predefined temperature in said treatment device prior to said temperature measurement phase.

7. The system of claim 6 , wherein the controller is configured to control the temperature regulator and flushes the treatment device prior to said treatment measurement phase to fill a blood compartment of said treatment device with treatment fluid at said predefined temperature.

8. The system of claim 7 , wherein the predefined temperature is a normal body temperature.

9. The system of claim 1 , wherein the controller is programmed to calculate said inlet temperature based on a constant heat transfer rate for all of said at least two flow rates.

10. The system of claim 9 , wherein the controller is programmed to calculate the inlet temperature responsively to an initial estimate of the inlet temperature, the initial estimate being calculated responsively to the first and second temperature data or estimated from a predefined value or otherwise estimated, the controller calculating the inlet temperature responsively to the initial estimate, an estimated or measured value of an ambient temperature, and the at least two flow rates.

11. The system of claim 10 wherein an improved inlet temperature estimate is responsive to a difference between the estimated or measured ambient temperature and an average of the initial estimate of the inlet temperature and the temperature indicated by said temperature signal.

12. A blood treatment method, comprising:
providing a blood pump and a temperature sensor, the blood pump and temperature sensor being configured to receive a predefined fluid circuit having a blood circuit with a blood inlet;
providing a controller connected to the blood pump to control a speed thereof and to the temperature sensor to receive a temperature signal output therefrom;
the temperature sensor being configured to detect a temperature of blood carried by the blood circuit;
using the controller, operating the pump at at least two flow rates;
for each of the at least two flow rates, using the controller, recording first and second temperature data responsive to the temperature signal at each of said at least two flow rates;
using the controller, calculating an inlet temperature responsively to both the first and second temperature data such that the inlet temperature is an estimation of the temperature at a point in said blood circuit remote from the temperature sensor and the calculating compensates for a temperature change in flowing blood between said point and said temperature sensor.

13. The method of claim 12 , further comprising, using the controller, displaying said inlet temperature on a display of a user interface.

14. The method of claim 12 , further comprising using the controller: controlling a treatment fluid pump, the treatment fluid pump engaging a treatment fluid circuit of said predefined fluid circuit; controlling said blood pump at said at least two flow rates during a temperature measurement phase of a startup mode of said controller, the startup mode including priming said blood circuit.

15. The method of claim 14 , wherein, during the temperature measurement phase of the startup mode, using the controller, controlling the treatment fluid pump to prevent flow in the treatment fluid circuit.

16. The method of claim 15 , wherein the predefined fluid circuit has treatment device that forms a heat transfer interface between the treatment fluid circuit and the blood circuit such that heat is transferred between the blood in the blood circuit and treatment fluid in the treatment fluid circuit.

17. The method of claim 16 , wherein a temperature regulator engages the treatment fluid circuit, further comprising, using the controller, controlling the temperature regulator and said treatment fluid pump, bringing a treatment fluid to a predefined temperature in said treatment fluid device prior to said temperature measurement phase.

18. The method of claim 17 , further comprising, using the controller, controlling the temperature regulator and flushing the treatment device prior to said treatment measurement phase to fill a non-blood compartment of said treatment device with treatment fluid at said predefined temperature.

19. The method of claim 18 , wherein the predefined temperature is a normal body temperature.

20. The method of claim 19 , wherein the calculating the inlet temperature includes calculating based on a constant heat transfer rate for all of said at least two flow rates.

21. The method of claim 20 , wherein the calculating the inlet temperature is responsive to an initial estimate of the inlet temperature, the initial estimate being based on the constant heat transfer rate or a predefined value, the calculating the inlet temperature being responsive to an improved inlet temperature estimate derived from the initial estimate of the inlet temperature, an estimated or measured of an ambient temperature, the first and second temperature data, and the at least two flow rates.

22. The method of claim 21 , wherein the improved inlet temperature estimate is responsive to a difference between the estimated or measured ambient temperature and an average of the initial estimate of the inlet temperature and th

Assignees

• Nxstage Medical Inc

Inventors

• Newell Scott W
• Treu Dennis M
• James Jerome

Classifications

• A61M1/36 Primary

  Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation {; Extra-corporeal blood circuits} · CPC title

• A61M1/3623

  Means for actively controlling temperature of blood · CPC title

• A61M2230/50

  Temperature · CPC title

• G05D23/1928

  sensing the temperature of one space · CPC title

• A61M2205/3372

  Temperature compensation · CPC title