Lyophilization

Patent metadata

Field	Value
Publication number	US-11067336-B2
Application number	US-202016736404-A
Country	US
Kind code	B2
Filing date	Jan 7, 2020
Priority date	Jun 9, 2014
Publication date	Jul 20, 2021
Grant date	Jul 20, 2021

Abstract

Embodiments of methods, systems, and apparatuses for lyophilizing, storing, and transfusing materials are described. In embodiments, the materials may include whole blood or a component of whole blood such as plasma.

First claim

What is claimed is:

1. A system for use in lyophilizing a material, the system comprising:
a first plate with a first surface, said first surface having a plurality of alternating concave and convex segments;
a second plate with a second surface opposed to the first surface, said second surface having a plurality of alternating convex and concave segments, the second plate comprising channels for circulating a fluid; wherein each cancave segment on the first surface faces a convex segment on said second surface and each convex segment on said first surface faces a concave segment on said second surface, and
a plate moving system operable to increase and decrease a space between the first surface and the second surface.

2. The system of claim 1 , further comprising an IR radiating material on the first plate, the IR radiating material comprising the first surface.

3. The system of claim 1 wherein the first surface of the first plate comprises a plurality of convex and concave half spheres and the second surface of the second plate comprises a plurality of concave and convex half spheres.

4. The system of claim 3 wherein the convex and concave half spheres of the first surface of the first plate are arranged in a regular pattern and the concave and convex half spheres of the second surface of the second plate are arranged in a corresponding regular pattern.

5. The system of claim 4 wherein the convex and concave half spheres of the first surface of the first plate are the same size and the concave and convex half spheres of the second surface of the second plate are the same size.

6. The system of claim 4 wherein the convex and concave half spheres of the first surface of the first plate are a plurality of different sizes size the concave and convex half spheres of the second surface of the second plate are a plurality of different sizes.

7. the system of claim 3 wherein the convex and concave half spheres of the first surface of the first plate are arranged in an irregular pattern and the concave and convex half spheres of the second surface of the second plate are arranged in a corresponding irregular pattern.

8. The system of claim 7 wherein the convex and concave half spheres of the first surface of the first plate are the same size and the concave and convex half spheres of the second surface of the second plate are the same size.

9. The system of claim 7 wherein the convex and concave half spheres of the first surface of the first plate are a plurality of different sizes size the concave and convex half spheres of the second surface of the second plate are a plurality of different sizes.

Assignees

• Terumo Bct Inc

Inventors

• Corbin Iii Frank
• Hlavinka Dennis J
• Pareta Rajesh
• Hillam Mark E

Classifications

• A61L2103/09

  Blood or products thereof · CPC title

• A01N1/165

  Pressure processes, e.g. following predefined pressure changes over time · CPC title

• A01N1/162

  Temperature processes, e.g. following predefined temperature changes over time · CPC title

• A01N1/146

  Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving · CPC title

• A01N1/144

  for temperature control, e.g. refrigerators or freeze-drying apparatus · CPC title