Renal failure therapy system and method of cleaning using citric acid

Patent metadata

Field	Value
Publication number	US-11065374-B2
Application number	US-201716326095-A
Country	US
Kind code	B2
Filing date	Aug 16, 2017
Priority date	Aug 18, 2016
Publication date	Jul 20, 2021
Grant date	Jul 20, 2021

Abstract

A renal failure therapy system ( 10 a, 10 b ) includes a dialysis fluid circuit ( 30 ) including a dialysis fluid pump ( 54, 58 ); a source ( 86, 90 ) of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit; a source ( 22 ) of purified water in fluid communication with the dialysis fluid circuit; and a logic implementer ( 20 ) in operable communication with the dialysis fluid pump ( 54,58 ), the logic implementer ( 20 ) causing the physiological cleaning, disinfecting, and/or decalcifying substance from its source ( 86, 90 ) to be added to purified water from the purified water source ( 22 ) to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump ( 54,58 ) to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit ( 30 ) without a subsequent rinse.

First claim

The invention is claimed as follows:

1. A renal failure therapy system comprising:
a dialysis fluid circuit including a dialysis fluid pump;
a source of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit;
a source of purified water in fluid communication with the dialysis fluid circuit; and
a logic implementer in operable communication with the dialysis fluid pump, wherein the logic implementer is programmed such that the system is configured to:
cause the physiological cleaning, disinfecting, and/or decalcifying substance to be added from its source to purified water from the purified water source to form a mixture,
circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump to at least one of clean, disinfect, or decalcify at least a portion of the dialysis fluid circuit without a subsequent rinse after circulating and moving directly to a drain sequence,
cause a portion of the mixture to be drained in the drain sequence, wherein draining a portion of the mixture from the dialysis fluid circuit includes trapping air in the dialysis fluid circuit, and

cause a filling procedure for a second treatment to begin with a portion of the mixture remaining in the dialysis fluid circuit, wherein the filling procedure reduces the remaining mixture to a lower level and removes a portion of the remaining mixture to drain.

2. The renal failure therapy system of claim 1 , wherein the physiological cleaning, disinfecting, and/or decalcifying substance includes an acid.

3. The renal failure therapy system of claim 2 , wherein the acid is at least partially citric acid.

4. The renal failure therapy system of claim 1 , wherein the physiological cleaning, disinfecting, and/or decalcifying substance includes citric acid in combination with a physiologically safe substance.

5. The renal failure therapy system of claim 1 , wherein the threshold amount is one percent of an amount of physiological cleaning, disinfecting, and/or decalcifying substance added from its source to purified water to form the mixture.

6. The renal failure therapy system of claim 1 , wherein the filling procedure involves an introduction of a bicarbonate substance from a source that neutralizes the physiological cleaning, disinfecting, and/or decalcifying substance.

7. The renal failure therapy system of claim 1 , wherein the filling procedure removes at least one percent of an original amount of the physiological cleaning, disinfecting, and/or decalcifying substance.

8. The renal failure therapy system of claim 1 , which includes a heater, the logic implementer programmed to control the heater such that a filling fluid is introduced to the dialysis fluid circuit during the filling procedure at a temperature below 35° C.

9. The renal failure therapy system of claim 8 , wherein the logic implementer is further programmed to cause the heater to heat the mixture while at least one of cleaning, disinfecting, or decalcifying the at least a portion of the dialysis fluid circuit.

10. The renal failure therapy system according to claim 1 , which includes at least one of (i) a keyed connector for the source of physiological cleaning, disinfecting, and/or decalcifying substance and a mating keyed connector for dialysis fluid circuit, or (ii) a marking associated with the source of physiological cleaning, disinfecting, and/or decalcifying substance and a scanner, reader, RFID reader, or camera in communication with logic implementer for reading the marking, upon which the logic implementer can allow or confirm the circulating of the mixture without the subsequent rinse.

11. The renal failure therapy system according claim 1 , wherein the dialysis fluid circuit includes a disinfection recirculation loop and an air separation chamber located within the loop, the air separation chamber increasing at least one of a flowrate and a heating efficiency of the physiological cleaning, disinfecting, and/or decalcifying substance flowing within the disinfection recirculation loop.

12. The renal failure therapy system according claim 1 , wherein the logic implementer is further programmed to:
cause purified water to flow from the source of purified water to a drain, the purified water flow causes remaining pockets of the physiological cleaning, disinfecting, and/or decalcifying substance and air to be flushed to drain; and
add a concentrate to the purified water to form dialysis fluid,
wherein forming the dialysis fluid causes the at least a portion of the remaining part of the mixture to be removed to drain.

13. A renal failure therapy machine operable with a source of physiological cleaning, disinfecting, and/or decalcifying substance and a source of purified water, the machine comprising:
a dialysis fluid circuit including a dialysis fluid pump, the dialysis fluid circuit configured to pump from the physiological cleaning, disinfecting, and/or decalcifying substance source and the purified water source; and
a logic implementer in operable communication with the dialysis fluid pump, the logic implementer programmed such that the machine is configured to cause:
the physiological cleaning, disinfecting, and/or decalcifying substance from its source to be added to purified water from the purified water source to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit after a first treatment,
a portion of the mixture to be drained in a drain sequence that begins directly after circulation of the mixture and without a separate rinsing sequence in between, wherein the drain sequence includes trapping air in the dialysis fluid circuit while draining the portion of the mixture, and
a filling procedure for a second treatment to begin directly after the drain sequence, and without a separate rinsing sequence in between, with the mixture remaining in the dialysis fluid circuit, the filling procedure relied upon to reduce the mixture remaining to a lower level.

14. The renal failure therapy machine of claim 13 , wherein the logic implementer is programmed to circulate the mixture within the dialysis fluid circuit from about one to about thirty minutes.

15. The renal failure therapy machine of claim 13 , wherein, during the filling procedure, at least one percent of an original amount of the physiological cleaning, disinfecting, and/or decalcifying substance is removed.

16. The renal failure therapy machine according to claim 13 , wherein, during the filling procedure, a bicarbonate substance from a source is provided, which neutralizes the physiological cleaning, disinfecting, and/or decalcifying substance.

17. The renal failure therapy machine according to claim 13 , wherein the drained portion of the mixture is a first portion, and wherein the logic implementer is further programmed to move to the second treatment including performing a filling procedure that drains a second portion of the mixture.

Assignees

• Gambro Lundia Ab

Inventors

• Hobro Sture
• Fors Jonas
• Jansson Olof

Classifications

• A61M1/168 Primary

  Sterilisation or cleaning before or after use · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title

• A61M1/169

  using chemical substances · CPC title

• A61M1/3643

  Priming, rinsing before or after use · CPC title

• A61M1/1605

  Physical characteristics of the dialysate fluid · CPC title