Post-steam sterilization moisture-indicating articles

Patent metadata

Field	Value
Publication number	US-11065354-B2
Application number	US-201414775745-A
Country	US
Kind code	B2
Filing date	Mar 7, 2014
Priority date	Mar 15, 2013
Publication date	Jul 20, 2021
Grant date	Jul 20, 2021

Abstract

Post-steam sterilization wet pack indicators are described. The indicators generally comprise a moisture-impermeable layer having a first surface and a moisture-indicating layer comprising a reversible colorimetric steam-sterilization-compatible moisture-indicating medium. The moisture-indicating layer is disposed on or near the first surface of the moisture-impermeable layer. The area of the moisture-indicating layer is dimensionally smaller than the moisture-impermeable layer such that the edges of the moisture-impermeable layer extend beyond the edges of the moisture-indicating layer. Articles and packages comprising wet pack indicators are also described.

First claim

What is claimed is:

1. A moisture-indicating article comprising:
a moisture-permeable material;
a moisture-impermeable layer peripherally bonded to the moisture-permeable material;
a moisture-indicating layer disposed between the moisture-permeable material and the moisture-impermeable layer; and
a color-enhancing layer located proximate the moisture-indicating layer such that a visual comparison between the color-enhancing layer and the moisture-indicating layer can be made;
wherein the moisture-indicating layer comprises a colorimetric reversible steam-sterilization-compatible moisture-indicating medium comprising a solid metal oxide support, a bis-glyoxime-transition metal complex bound to the solid metal oxide support, and a silyl-containing compound bound to the solid metal oxide support through a silanol bond with at least one hydroxyl group on the surface of the solid metal oxide support.

2. The moisture-indicating article of claim 1 , further comprising at least one middle layer disposed between the moisture-impermeable layer and the moisture-indicating layer.

3. The moisture-indicating article of claim 2 , wherein the at least one middle layer is selected from the group consisting of an impermeable layer, an adhesive layer, and a wicking layer, and the color-enhancing layer.

4. The moisture-indicating article of claim 1 , further comprising at least one moisture-penetrable lower layer disposed between the moisture-indicating layer and the moisture-permeable material.

5. The moisture-indicating article of claim 4 , wherein the at least one moisture-penetrable lower layer is selected from the group consisting of an adhesive layer, a color-enhancing layer, a challenge layer, and a wicking layer.

6. A post-steam sterilization wet pack indicator comprising:
a moisture-impermeable layer having a recess; and
a moisture-indicating layer disposed within the recess;
wherein the moisture-indicating layer comprises a reversible colorimetric steam-sterilization-compatible moisture-indicating medium comprising a solid metal oxide support, a bis-glyoxime-transition metal complex bound to the solid metal oxide support, and a silyl-containing compound bound to the solid metal oxide support through a silanol bond with at least one hydroxyl group on the surface of the solid metal oxide support; and
wherein the edges of the moisture-impermeable layer extend beyond the recess.

7. The moisture-indicating article of claim 1 , wherein the moisture-indicating layer is a first color when the moisture-indicating layer is in a dry state, wherein the moisture-indicating layer is a second color when the moisture-indicating layer is in a wet state, wherein the color-enhancing layer is a third color, wherein the first color and the third color are the same color.

8. The moisture-indicating article of claim 1 , wherein the moisture-indicating layer is a first color when the moisture-indicating layer is in a dry state, wherein the moisture-indicating layer is a second color when the moisture-indicating layer is in a wet state, wherein the color-enhancing layer is a third color, wherein the second color and the third color are the same color.

9. The moisture-indicating article of claim 1 , wherein the moisture-impermeable layer has a first surface, wherein the color-enhancing layer is disposed on a surface of the moisture-impermeable layer opposite the first surface.

10. The moisture-indicating article of claim 1 , wherein the color-enhancing layer is disposed between the moisture-impermeable layer and the moisture-indicating layer.

11. The moisture-indicating article of claim 1 , wherein the color-enhancing layer comprises a hole or transparent portion that creates a viewing area through which the moisture-indicating layer can be viewed.

12. The moisture-indicating article of claim 1 , wherein the silyl-containing compound is hydrophobic.

13. The post-steam sterilization wet pack indicator of claim 6 , wherein the silyl-containing compound is hydrophobic.

Assignees

• 3M Innovative Properties Co

Inventors

• Hajime Evan K L Y
• Kang Myungchan
• Nies Timothy J

Classifications

• A61L2/07

  Steam · CPC title

• A61B50/30

  Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments (for wound clamps A61B17/10; for ligaturing clips A61B17/122; packages or dispensers for surgical gloves or finger-stalls A61B42/40) · CPC title

• G01N31/222

  for investigating moisture content · CPC title

• A61L2/28 Primary

  Devices for testing the effectiveness or completeness of sterilisation or disinfection, e.g. indicators which change colour · CPC title