Method and apparatus for cardiac procedures

Patent metadata

Field	Value
Publication number	US-11065120-B2
Application number	US-201816167069-A
Country	US
Kind code	B2
Filing date	Oct 22, 2018
Priority date	Oct 24, 2017
Publication date	Jul 20, 2021
Grant date	Jul 20, 2021

Abstract

Described herein are methods and apparatus for approximating targeted tissue using locking sutures. The locking sutures can be configured to receive suture ends that are interweaved through portions of the locking sutures. In a pre-deployment configuration, a locking suture can slide along suture tails and can be positioned at a target location within a target region. Once a desired position and/or tension is achieved, the locking suture can be transitioned to a post-deployment configuration where the locking suture constricts around the suture tails to inhibit relative movement between the suture tails and the locking suture.

First claim

What is claimed is:

1. A method for using locking sutures to approximate anchor implants attached to targeted tissue, the method comprising:
attaching two or more cords to targeted tissue, individual cords including a distal anchor implant and a suture extending proximally from the distal anchor implant;
intertwining proximal end portions of the two or more sutures with a knot of a locking suture, the locking suture including a tether portion extending from the knot and configured to be manipulated to transition the knot from a delivery configuration to a deployed configuration;
positioning the knot of the locking suture relative to the two or more sutures by sliding the knot along the two or more sutures to approximate portions of the targeted tissue; and
transitioning the knot from the delivery configuration to the deployed configuration to lock the locking suture by creating a confined tortuous path for the two or more sutures through the knot of the locking suture.

2. The method of claim 1 , wherein transitioning the knot to the deployed configuration does not increase proximal forces on the targeted tissue.

3. The method of claim 1 , wherein the targeted tissue is within a targeted region and positioning the knot is done utilizing a locking suture device that is operated outside of the targeted region.

4. The method of claim 3 , wherein the targeted region is the heart.

5. The method of claim 4 further comprising anchoring the proximal end portions of the two or more sutures.

6. The method of claim 5 , wherein anchoring the proximal end portions of the two or more sutures includes securing the proximal end portions to an external wall of the heart.

7. The method of claim 1 , wherein the targeted tissue includes a leaflet of a mitral valve.

8. The method of claim 1 further comprising securing the knot to a distal end of a locking suture delivery device.

9. The method of claim 8 , wherein transitioning the knot to the deployed configuration includes manipulating an element of the locking suture delivery device to which the locking suture is secured.

10. The method of claim 8 further comprising applying sequential proximal forces to the proximal end portions of the two or more sutures using the locking suture delivery device.

11. The method of claim 1 , wherein positioning the locking suture along the sutures of the two or more sutures results in a point of intersection that approaches the targeted tissue to change a force vector on the two or more cords attached to the targeted tissue.

12. The method of claim 1 wherein locking the locking suture includes constricting the knot to secure the knot to the two or more sutures.

13. The method of claim 1 wherein locking the locking suture inhibits relative motion between the knot and the two or more sutures in the deployed configuration.

14. The method of claim 1 wherein the knot forms multi-turn coils.

15. The method of claim 14 wherein intertwining proximal end portions of the two or more sutures with the knot includes feeding the proximal end portions of the two or more sutures through the multi-turn coils of the knot.

16. The method of claim 1 wherein, in the delivery configuration, the knot is sufficiently loose to allow the knot to slide along the two or more sutures and, in the deployed configuration, the knot is sufficiently tight to inhibit relative motion between the knot and the two or more sutures.

17. The method of claim 1 wherein, in the deployed configuration, the knot is constricted to create a tortuous path for the two or more sutures intertwined with the knot.

18. The method of claim 1 wherein transitioning the knot from the delivery configuration to the deployed configuration comprises applying a proximal force on the tether portion of the locking suture.

19. The method of claim 1 wherein the knot is in the form of braided, twisted, coiled, looped, or knotted sutures that is configured so that application of a proximal force on the tether portion causes the knot to constrict on the two or more sutures intertwined with the knot.

20. The method of claim 1 further comprising receiving feedback from a visualization system, the feedback including an approximation of the targeted tissue.

Assignees

• Univ Maryland
• Harpoon Medical Inc

Inventors

• Cortez Jr Felino V
• Gammie James S
• Wilson Peter
• Zanetti Luke Anthony
• Etheridge Julie Marie
• Cournane Stephen

Classifications

• A61B17/0469 Primary

  Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery · CPC title

• A61B17/0485

  Devices or means, e.g. loops, for capturing the suture thread and threading it through an opening of a suturing instrument or needle eyelet · CPC title

• A61B2090/08021

  of the patient or his organs · CPC title

• A61B2017/0406

  Pledgets · CPC title

• A61B17/0482

  Needle or suture guides (guides for drills, pins or wire A61B17/17; guides for puncturing needles A61B17/3403) · CPC title