Analyte sensor

Patent metadata

Field	Value
Publication number	US-11064917-B2
Application number	US-202117161103-A
Country	US
Kind code	B2
Filing date	Jan 28, 2021
Priority date	Jul 13, 2004
Publication date	Jul 20, 2021
Grant date	Jul 20, 2021

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

First claim

What is claimed is:

1. A glucose monitoring system comprising:
a transcutaneous glucose sensor comprising:
an in vivo portion configured to be inserted into a body of a host; and
an ex vivo portion configured to remain outside of the body of the host;

sensor electronics configured to operably connect to the transcutaneous glucose sensor, wherein the sensor electronics comprise:
a memory configured to store prior calibration information, wherein the prior calibration information comprises prior sensitivity information associated with the transcutaneous glucose sensor; and
a radio frequency transceiver; and

a receiver comprising a processor, wherein the receiver is configured to:
initiate, in response to the receiver interrogating the sensor electronics, a sensor duration time period associated with sensor life and a transmission of the prior calibration information from the sensor electronics to the receiver;
calibrate sensor data based at least in part on the prior calibration information generated before insertion of the transcutaneous glucose sensor in the host, wherein the sensor data is derived at least in part from the transcutaneous glucose sensor and is associated with a glucose concentration of the host, wherein the processor is programmed to calibrate the sensor data without a need for a reference analyte concentration measurement obtained after insertion of the in vivo portion of the transcutaneous glucose sensor; and
cease further display of an estimated glucose concentration value, associated with the sensor data, on the receiver upon an end of the sensor duration time period.

2. The system of claim 1 , wherein the receiver interrogating the sensor electronics comprises an inductive coupling between the receiver and the sensor electronics.

3. The system of claim 1 , wherein the receiver interrogating the sensor electronics occurs when the receiver is in close proximity to the sensor electronics.

4. The system of claim 1 , wherein the prior calibration information is derived at least in part from a predictive relationship between an in vitro sensor sensitivity to glucose and an in vivo sensor sensitivity to glucose.

5. The system of claim 1 , wherein the reference analyte concentration measurement is a finger stick blood sample obtained from the host after insertion of the in vivo portion of the transcutaneous glucose sensor in the host.

6. The system of claim 1 , wherein the receiver comprises a cell phone.

7. The system of claim 1 , wherein the receiver comprises an application-specific device.

8. The system of claim 1 , wherein the sensor duration time period associated with sensor life is 7 days or more.

9. An analyte monitoring system comprising:
a transcutaneous analyte sensor comprising:
an in vivo portion configured to be inserted into a body of a host; and
an ex vivo portion configured to remain outside of the body of the host; and

a processor programmed to:
trigger, in response to a user activity, a sensor duration for the transcutaneous analyte sensor;
calibrate sensor data based at least in part on prior calibration information generated before insertion of the in vivo portion of the transcutaneous analyte sensor in the host, wherein the sensor data is associated with an analyte concentration of the host, wherein the prior calibration information comprises prior sensitivity information associated with the transcutaneous analyte sensor, wherein the processor is programmed to calibrate the sensor data without a need for a reference analyte concentration measurement obtained after insertion of the in vivo portion of the transcutaneous analyte sensor in the host; and
trigger a shut down of display of one or more estimated analyte concentration values associated with the sensor data after expiration of the sensor duration.

10. The system of claim 9 , further comprising:
sensor electronics configured to operably connect to the transcutaneous analyte sensor; and
a receiver comprising a display, wherein the display is configured to display the one or more estimated analyte concentration values before expiration of the sensor duration.

11. The system of claim 10 , wherein the processor is incorporated in the receiver.

12. The system of claim 10 , wherein the processor is incorporated in the sensor electronics.

13. The system of claim 10 , wherein the processor comprises a sensor electronics processor and a receiver processor.

14. The system of claim 9 , wherein the prior sensitivity information is derived at least in part from a predictive relationship between an in vitro sensor sensitivity to glucose and an in vivo sensor sensitivity to glucose.

15. The system of claim 9 , wherein the reference analyte concentration measurement is a finger stick blood sample obtained from the host after insertion of the in vivo portion of the transcutaneous analyte sensor in the host.

16. The system of claim 9 , wherein the shut down of display of one or more estimated analyte concentration values comprises ceasing calibration of sensor data after expiration of the sensor duration.

17. The system of claim 9 , wherein the shut down of display of one or more estimated analyte concentration values comprises ceasing transmission of sensor data after expiration of the sensor duration.

18. The system of claim 9 , wherein the shut down of display of one or more estimated analyte concentration values comprises disabling a display after expiration of the sensor duration.

19. The system of claim 9 , wherein the shut down of display of one or more estimated analyte concentration values comprises rendering the transcutaneous analyte sensor inoperable after expiration of the sensor duration.

20. The system of claim 9 , wherein the user activity comprises interfacing with a user interface.

21. The system of claim 9 , wherein the user activity comprises inserting the in vivo portion of the transcutaneous analyte sensor into the body of the host.

22. The system of claim 9 , wherein the user activity comprises inductive coupling between a receiver and electronics associated with the transcutaneous analyte sensor.

23. The system of claim 22 , wherein the receiver comprises a cell phone.

24. The system of claim 9 , wherein the sensor duration is 7 days or more.

25. An analyte monitoring system comprising:
a transcutaneous analyte sensor comprising:
an in vivo portion configured to be inserted into a body of a host; and
an ex vivo portion configured to remain outside of the body of the host; and

at least one processor programmed to:
trigger initialization of a duration time for expiration of the transcutaneous analyte sensor in response to an inductive coupling; and
calibrate sensor data based at least in part on prior calibration information generated before insertion of the in vivo portion of the transcutaneous analyte sensor in the host, wherein the sensor data is associated with an analyte concentration of the host, wherein the prior calibration information comprises sensitivity information associated with the transcutaneous analyte sensor, wherein the sensor data is calibrated without a need for a reference analyte concentration measurement obtained after insertion of the in vivo portion of the transcutaneous analyte sensor.

26. The system of claim 25 , further comprising:
sensor electronics configured to be worn on the body of the host and configured to operably connect with t

Assignees

• Dexcom Inc

Inventors

• Simpson Peter C
• Brauker James H
• Brister Mark C
• Goode Jr Paul V
• Kamath Apurv Ullas
• Mahalingam Aarthi
• Pryor Jack
• Wightlin Matthew D

Classifications

• A61B2560/063

  Devices specially adapted for delivering implantable medical measuring apparatus · CPC title

• A61B5/1451

  for interstitial fluid · CPC title

• A61B5/0031

  Implanted circuitry · CPC title

• A61B2562/18

  Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage · CPC title

• A61B5/14507

  specially adapted for measuring characteristics of body fluids other than blood (devices for taking samples of body liquids A61B10/0045) · CPC title