Regulatory T cell activator and use thereof

US11059888B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11059888-B2
Application numberUS-201716095024-A
CountryUS
Kind codeB2
Filing dateApr 19, 2017
Priority dateApr 20, 2016
Publication dateJul 13, 2021
Grant dateJul 13, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A regulatory T cell activator including a substance that inhibits the binding between DNAX accessory molecule-1 (DNAM-1) and CD155.

First claim

Opening claim text (preview).

The invention claimed is: 1. An anti-human DNAM-1 monoclonal antibody or a fragment thereof, comprising a heavy-chain variable region having the amino acid sequence of SEQ ID NO: 7 and a light-chain variable region having the amino acid sequence of SEQ ID NO: 8. 2. The anti-human DNAM-1 monoclonal antibody or a fragment thereof according to claim 1 , the antibody or a fragment thereof being a humanized antibody or a fragment of a humanized type antibody.

Assignees

Inventors

Classifications

  • Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change · CPC title

  • Cells modified by introduction of foreign genetic material · CPC title

  • Antagonist effect on antigen, e.g. neutralization or inhibition of binding · CPC title

  • Complementarity determining region [CDR] · CPC title

  • from primates, e.g. man · CPC title

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Frequently asked questions

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What does patent US11059888B2 cover?
A regulatory T cell activator including a substance that inhibits the binding between DNAX accessory molecule-1 (DNAM-1) and CD155.
Who is the assignee on this patent?
Univ Tsukuba
What technology area does this patent fall under?
Primary CPC classification A61K39/395. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jul 13 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 4 related publications on this page (citations in our corpus or others sharing the same primary CPC).