Alpha-cinnamide compounds and compositions as hdac8 inhibitors
US-2016264518-A1 · Sep 15, 2016 · US
US11059775B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11059775-B2 |
| Application number | US-201716461630-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 20, 2017 |
| Priority date | Nov 18, 2016 |
| Publication date | Jul 13, 2021 |
| Grant date | Jul 13, 2021 |
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Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed.
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That which is claimed: 1. A compound selected from the group consistinq of: and stereoisomers and pharmaceutically acceptable salts thereof.
Ethylene carbonate · CPC title
having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms · CPC title
Vinylene carbonate; Substituted vinylene carbonates · CPC title
with oxygen atoms in positions 1 and 3, e.g. phthalimide · CPC title
having oxygen atoms of hydroxylamino groups etherified · CPC title
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