Detection of a disruption of a fluid connection between two fluid containing systems

Patent metadata

Field	Value
Publication number	US-11058810-B2
Application number	US-201716098032-A
Country	US
Kind code	B2
Filing date	May 11, 2017
Priority date	Jun 30, 2016
Publication date	Jul 13, 2021
Grant date	Jul 13, 2021

Abstract

A monitoring device implements a monitoring method that comprises: activating a first monitoring technique that operates to detect the disruption and generate a corresponding alarm signal while a second monitoring technique is deactivated, obtaining at least one of a first count of false alarms generated by the primary monitoring technique and a second count of false alarms generated by the second monitoring technique if activated, and selectively, based on at least one of the first and second counts, activating the second monitoring technique to operate, instead of or jointly with the first monitoring technique, to detect the disruption and generate the corresponding alarm signal. The monitoring device may be connected to or part of an apparatus for blood treatment and operable to detect a disconnection of an extracorporeal blood circuit from a vascular system of a patient, e.g. a venous-side disconnection.

First claim

The invention claimed is:

1. A monitoring device, comprising:
an input interface for receiving one or more measurement signals from one or more sensors arranged in or associated with a first fluid containing system and/or a second fluid containing system, the one or more measurement signals being responsive to a disruption of a fluid connection between the first fluid containing system and the second fluid containing system,
a first disruption detector and a second disruption detector, each being configured to operate a respective detection logic on at least one of the one or more measurement signals to detect apparent disruptions of the fluid connection and provide alarm indications corresponding to the apparent disruptions,
an alarm module for generating an alarm signal based on the alarm indications, and
a switching module configured to operate the monitoring device in one of a first mode, in which at least the first disruption detector is operated and the alarm signal is generated based only on the alarm indications provided by the first disruption detector, and a second mode, in which at least the second disruption detector is operated and the alarm signal is based at least on the alarm indications provided by the second disruption detector,
wherein the switching module is configured to, when operating the monitoring device in the first mode, obtain at least one of a first count of false alarm indications provided per unit time by the first disruption detector and a second count of false alarm indications provided per unit time by the second disruption detector, and selectively, based on at least one of the first and second counts, switch the monitoring device to the second mode.

2. The monitoring device of claim 1 , wherein the switching module is configured to switch the monitoring device from the first mode to the second mode when the first count exceeds a predefined first limit and/or when the second count is below a predefined second limit.

3. The monitoring device of claim 1 , wherein the switching module is configured to, when operating the monitoring device in the second mode, operate the first disruption detector and the second disruption detector to provide the alarm indications, obtain at least one of the first and second counts, and selectively, based on the at least one of the first and second counts, switch the monitoring device to the first mode.

4. The monitoring device of claim 3 , wherein the switching module is configured to selectively switch the monitoring device from the second mode to the first mode when the first count is below a predefined second limit and/or when the second count exceeds a predefined fourth limit.

5. The monitoring device of claim 1 , wherein the switching module is configured to operate the monitoring device in the second mode so that the alarm signal is generated based only on the alarm indications provided by the second disruption detector.

6. The monitoring device of claim 1 , wherein the switching module is configured to operate the monitoring device in the second mode so that the alarm signal is generated based on the alarm indications provided by the second disruption detector and the alarm indications provided by the first disruption detector.

7. The monitoring device of claim 1 , wherein each of the first and second disruption detectors is configured to, when operating the respective detection logic, generate a time-sequence of parameter values of a detection parameter to represent a time segment in the at least one measurement signal, compare the time-sequence of parameter values to an allowable range, and provide the alarm indications when a predefined number of parameter values in the time-sequence of parameter values fall outside the allowable range.

8. The monitoring device of claim 7 , wherein the detection logics of the first and second disruption detectors differ by at least one of: the at least one measurement signal, preprocessing of the at least one measurement signal, the detection parameter, the current allowable range, and the predefined number of parameter values.

9. The monitoring device of claim 7 , wherein the second disruption detector is configured to obtain the at least one measurement signal from at least one pressure sensor in the first fluid containing system, and generate the time-sequence of parameter values to be indicative of a pressure level in the first fluid containing system.

10. The monitoring device of claim 7 , wherein the first disruption detector is configured to obtain the at least one measurement signal from at least one pressure sensor in the first fluid containing system, and generate the time-sequence of parameter values to represent pulsations originating from a pulse generator in or associated with the second fluid containing system.

11. The monitoring device of claim 1 , wherein the first disruption detector is configured to perform an automatic validation of each alarm indication to determine the alarm indication as a false alarm indication or a true alarm indication, and wherein the monitoring device comprises a false alarm analyzer configured to produce the first count based on the false alarm indications determined by the automatic validation.

12. The monitoring device of claim 11 , wherein the automatic validation involves one or more of: obtaining and processing a further measurement signal among the one or more measurement signals; generating parameter values of another detection parameter as a function of the at least one measurement signal; and intermittently disabling one or more sources of signal interferences in the at least one measurement signal.

13. The monitoring device of claim 11 , wherein the first fluid containing system comprises a blood processing apparatus for connection, by the fluid connection, to a subject, wherein the one or more sensors comprise a pressure sensor for sensing a pressure of blood in the blood processing apparatus, wherein the automatic validation comprises: obtaining and processing the at least one measurement signal for detection of pulsations originating from a pulse generator in or associated with the subject.

14. The monitoring device of claim 13 , wherein the automatic validation comprises, before obtaining and processing the at least one measurement signal, generating a control signal to stop one or more pumping devices arranged in the blood processing apparatus.

15. The monitoring device of claim 11 , wherein the alarm module is configured to generate the alarm signal based on the true alarm indications.

16. An apparatus for extracorporeal blood processing, comprising:
an extracorporeal blood circuit for connection in fluid communication with the vascular system of a patient at first and second ends and comprising a blood pump for circulating blood from the first end through a blood processing device to the second end;
at least one sensor configured to generate at least one measurement signal which is responsive to a disconnection of the extracorporeal blood circuit from the vascular system of the patient downstream of the blood pump;
a first disruption detector and a second disruption detector, each being configured to operate a respective detection logic on at least one of the one or more measurement signals to detect the disconnection and provide an alarm indication corresponding to the disconnection,
an alarm module for generating an alarm signal based on the alarm indication, and
a switching module configured to operate the monitoring device in one of a first mode, in which at least the first disruption detector is operated and the alarm signal is gener

Assignees

• Gambro Lundia Ab

Inventors

• Sternby Jan
• Olde Bo

Classifications

• A61M2230/06

  Heartbeat rate only · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title

• A61M2205/15

  Detection of leaks · CPC title

• A61M2205/18

  with alarm · CPC title

• A61M1/3656 Primary

  Monitoring patency or flow at connection sites; Detecting disconnections · CPC title