Analyte sensor

Patent metadata

Field	Value
Publication number	US-11058330-B2
Application number	US-201815904940-A
Country	US
Kind code	B2
Filing date	Feb 26, 2018
Priority date	Feb 24, 2015
Publication date	Jul 13, 2021
Grant date	Jul 13, 2021

Abstract

Sensors and methods for measurement of an analyte in a medium within a living animal are described. The sensor may include an inductive element that may receive power from an external device. The sensor may also include a charge storage device (CSD) and a memory. The sensor may perform analyte measurements initiated by the external device using power received from the external device and convey the analyte measurements to the external device using the inductive element. The sensor also may perform autonomous analyte measurements using the on board charge device's power and store the autonomous analyte measurements in the memory. The sensor may convey one or more stored analyte measurements to the external device using the inductive element using power received from the external device. The sensor may include a CSD-powered clock and a CSD-powered measurement scheduler that initiate the autonomous analyte measurements.

First claim

What is claimed is:

1. A method of using a sensor to measure an analyte in a medium within a living animal, the method comprising:
controlling sensor elements of the sensor to generate a first analyte measurement signal using power provided by an electrodynamic field generated by an external device while an inductive element of the sensor is in the electrodynamic field generated by the external device, wherein the sensor elements are configured to generate the first analyte measurement signal based on a detectable property exhibited by an analyte indicator of the sensor, and the analyte indicator is configured to exhibit the detectable property based on the amount or concentration of the analyte in the medium;
generating first measurement information based on the first analyte measurement signal;
controlling an input/output circuit of the sensor to wirelessly convey the first measurement information to the external device via the inductive element while the inductive element is in the electrodynamic field generated by the external device;
using a power switch to switch at least the sensor elements from being powered by the electrodynamic field to being powered by a charge storage device of the sensor;
controlling the sensor elements of the sensor to generate a second analyte measurement signal using power provided by the charge storage device while the inductive element of the sensor is not in the electrodynamic field generated by the external device, wherein the sensor elements are configured to generate the second analyte measurement signal based on a detectable property exhibited by the analyte indicator of the sensor;
generating second measurement information based on the second analyte measurement signal;
storing the second measurement information in a nonvolatile storage medium of the sensor; and
controlling the input/output circuit of the sensor to wirelessly convey the stored second measurement information to the external device via the inductive element while the inductive element is in the electrodynamic field generated by the external device.

2. The method of claim 1 , further comprising:
using a measurement scheduler that is powered by the charge storage device to periodically determine that an interval of time has passed based on the output of a clock that is powered by the charge storage device; and
wherein switching at least the sensor elements from being powered by the electrodynamic field to being powered by the charge storage device is in response to a determination that the interval of time has passed.

3. A sensor comprising:
an analyte indicator configured to exhibit a detectable property based on the amount or concentration of an analyte in a medium within a living animal;
sensor elements configured to generate an analyte measurement signal based on the detectable property exhibited by the analyte indicator;
an inductive element configured to produce a current when in an electrodynamic field generated by an external device;
an input/output circuit;
a measurement controller;
a non-volatile storage medium;
a charge storage device;
a clock that is powered by the charge storage device; and
a measurement scheduler that is powered by the charge storage device and is configured to use an output of the clock to periodically determine that an interval of time has passed;
wherein the measurement controller is configured to, in response to a determination that the interval of time has passed:
(i) control the sensor elements to generate an analyte measurement signal using power provided by the charge storage device;
(ii) generate measurement information based on the analyte measurement signal; and
(iii) store the measurement information in the non-volatile storage medium;

wherein the input/output circuit is configured to wirelessly convey the measurement information to the external device via the inductive element; and
wherein the measurement controller is further configured to control the input/output circuit to wirelessly convey the measurement information to the external device while the inductive element is in the electrodynamic field generated by the external device.

4. A sensor comprising:
an analyte indicator configured to exhibit a detectable property based on the amount or concentration of an analyte in a medium within a living animal;
sensor elements configured to generate an analyte measurement signal based on the detectable property exhibited by the analyte indicator;
a measurement controller;
a non-volatile storage medium;
a charge storage device;
a clock that is powered by the charge storage device;
a measurement scheduler that is powered by the charge storage device and is configured to use an output of the clock to periodically determine that an interval of time has passed; and
a power switch;
wherein the measurement controller is configured to, in response to a determination that the interval of time has passed:
(i) control the sensor elements to generate an analyte measurement signal using power provided by the charge storage device;
(ii) generate measurement information based on the analyte measurement signal; and
(iii) store the measurement information in the non-volatile storage medium;

wherein the power switch is configured to switch one or more of the sensor elements and the measurement controller from being powered by an external device to being powered by the charge storage device in response to the determination that the interval of time has passed.

5. A method of using a sensor to measure an analyte in a medium within a living animal, the method comprising:
using a charge storage device of the sensor to power a measurement scheduler and a clock;
using the measurement scheduler to periodically determine that an interval of time has passed based on an output of the clock;
controlling sensor elements of the sensor to generate an analyte measurement signal using power provided by the charge storage device in response to a determination that the interval of time has passed, wherein the analyte measurement signal is based on a detectable property exhibited by an analyte indicator of the sensor, and the analyte indicator is configured to exhibit the detectable property based on the amount or concentration of the analyte in the medium;
generating measurement information based on the analyte measurement signal;
storing the measurement information in a non-volatile storage medium of the sensor; and
controlling an input/output circuit to wirelessly convey the measurement information to an external device via an inductive element while the inductive element is in an electrodynamic field generated by the external device.

6. A method using a sensor to measure an analyte in a medium within a living animal, the method comprising:
using a charge storage device of the sensor to power a measurement scheduler and a clock;
using the measurement scheduler to periodically determine that an interval of time has passed based on an output of the clock;
controlling sensor elements of the sensor to generate an analyte measurement signal using power provided by the charge storage device in response to a determination that the interval of time has passed, wherein the analyte measurement signal is based on a detectable property exhibited by an analyte indicator of the sensor, and the analyte indicator is configured to exhibit the detectable property based on the amount or concentration of the analyte in the medium;
generating measurement information based on the analyte measurement signal;
storing the measurement information in a non-volatile storage medium of the sensor; and
switching the sensor elements of the sensor from being powered by an external device to being powered by the charge storage device in response to the det

Assignees

• Senseonics Inc

Inventors

• Dehennis Andrew
• Tankiewicz Szymon
• Whitehurst Todd

Classifications

• A61B5/1459

  invasive, e.g. introduced into the body by a catheter · CPC title

• A61B5/0002

  Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07) · CPC title

• A61B5/0075

  by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence) · CPC title

• A61B5/14532 Primary

  for measuring glucose, e.g. by tissue impedance measurement · CPC title

• A61B2560/0214

  of power generation or supply · CPC title