Vascular device visibility

Patent metadata

Field	Value
Publication number	US-11045215-B2
Application number	US-201916363230-A
Country	US
Kind code	B2
Filing date	Mar 25, 2019
Priority date	Feb 12, 2016
Publication date	Jun 29, 2021
Grant date	Jun 29, 2021

Abstract

A medical device can include an elongate manipulation member, and a thrombectomy device connected to the elongate manipulation member. The thrombectomy device can have a first configuration and a second configuration, the thrombectomy device being expandable from the first configuration to the second configuration. The thrombectomy device can include an arcuate marker-mounting projection attached to a portion of the thrombectomy device configured to contact a thrombus. A marker can be coupled to, and extending around, the arcuate marker-mounting projection with the marker and the arcuate marker-mounting projection contacting each other at three discrete locations. A method for engaging a thrombus can include advancing a thrombectomy device to a location radially adjacent to a thrombus in a blood vessel. The thrombectomy device can be positioned such that a marker, disposed at a proximal end of a working length of thrombectomy device, is proximal to or longitudinally aligned with a proximal end of the thrombus, and can be expanded into the thrombus.

First claim

We claim:

1. A method for engaging a thrombus, the method comprising:
(a) advancing a thrombectomy device, using an elongate manipulation member, to a location radially adjacent to a thrombus in a blood vessel, the thrombectomy device comprising a working length and a non-working length, the non-working length comprising a mesh portion disposed between and separating the working length and a connection between the thrombectomy device and the elongate manipulation member, the non-working length having a connection marker disposed at the connection, the working length having a proximal end and a distal end with a plurality of proximal markers disposed at the proximal end, a plurality of distal markers, discrete from the proximal markers, disposed at the distal end, and a plurality of intermediate markers between the plurality of proximal markers and the plurality of distal markers;
(b) positioning the thrombectomy device relative to the thrombus such that all of the proximal markers are proximal to or longitudinally aligned with a proximal end of the thrombus and all of the distal markers are distal to or longitudinally aligned with a distal end of the thrombus;
(c), after (b), expanding the thrombectomy device into the thrombus;
(d) imaging the proximal, intermediate, and distal pluralities of markers to (i) determine whether a maximum marker separation of the plurality of intermediate markers is less than a maximum marker separation of either the plurality of proximal markers or the plurality of distal markers, and (ii) determine a state of engagement of the working length with the thrombus based on the positioning of the proximal, intermediate, and distal pluralities of markers.

2. The method of claim 1 , wherein, when the maximum marker separation of the plurality of intermediate markers is not less than the maximum marker separation of either the plurality of proximal markers or the plurality of distal markers, the method further comprises:
collapsing the thrombectomy device;
repositioning the thrombectomy device relative to the thrombus such that at least one of the plurality of proximal markers is proximal to or longitudinally aligned with a proximal end of the thrombus and at least one of the plurality of distal markers is distal to or longitudinally aligned with a distal end of the thrombus; and
re-expanding the thrombectomy device into the thrombus.

3. The method of claim 1 , wherein at least one of the proximal markers is located within 5 millimeters of the proximal end of the working length.

4. The method of claim 1 , wherein the thrombectomy device includes a plurality of cells, and wherein the plurality of proximal markers is located within one cell-length of the proximal end of the working length.

5. The method of claim 1 , wherein the thrombectomy device includes a plurality of arcuate marker-mounting projections.

6. The method of claim 5 , wherein each of the proximal markers is disposed on one of the marking-mounting projections.

7. The method of claim 5 , wherein each of the distal markers is disposed on one of the marking-mounting projections.

8. The method of claim 5 , wherein each of the intermediate markers is disposed on one of the marking-mounting projections.

9. A method for engaging a thrombus, the method comprising:
(a) advancing a thrombectomy device, using an elongate manipulation member, to a location radially adjacent to a thrombus in a blood vessel, the thrombectomy device comprising (i) a working length having a proximal end and a distal end with a plurality of proximal markers disposed at the proximal end, a distal marker at the distal end, and a plurality of intermediate markers distal of the plurality of proximal markers, and (ii) a non-working length comprising a mesh portion disposed between and separating the working length and a connection between the thrombectomy device and the elongate manipulation member, the non-working length having a connection marker disposed at the connection;
(b) positioning the thrombectomy device relative to the thrombus such that all of the proximal markers are proximal to or longitudinally aligned with a proximal end of the thrombus;
(c), after (b), expanding the thrombectomy device into the thrombus;
(d) imaging the proximal plurality of markers, the intermediate plurality of markers, and the distal marker to (i) determine whether a maximum marker separation of the plurality of intermediate markers is less than a maximum marker separation of the plurality of proximal markers, and (ii) determine a state of engagement of the working length with the thrombus by observing the proximal plurality of markers, the intermediate plurality of markers, and the distal marker.

10. The method of claim 9 , further comprising imaging the proximal end of the working length distinctly from the connection with the plurality of proximal markers.

11. The method of claim 9 , wherein the thrombectomy device has a body comprising a plurality of struts, and the distal marker and plurality of proximal markers are more radiopaque than the body.

12. The method of claim 9 , wherein at least one of the proximal markers is located within 5 millimeters of the proximal end of the working length.

13. The method of claim 9 , wherein the thrombectomy device includes a plurality of arcuate marker-mounting projections.

14. The method of claim 13 , wherein each of the proximal markers is disposed on one of the marking-mounting projections.

15. The method of claim 13 , wherein each of the intermediate markers is disposed on one of the marking-mounting projections.

16. The method of claim 13 , wherein the thrombectomy device comprises a plurality of struts forming a plurality of cells, and each of the arcuate marker-mounting projections extends from one of the struts.

17. The method of claim 9 , wherein, when the maximum marker separation of the plurality of intermediate markers is not less than the maximum marker separation of the plurality of proximal markers, the method further comprises:
collapsing the thrombectomy device;
repositioning the thrombectomy device relative to the thrombus such that the plurality of proximal markers are proximal to or longitudinally aligned with a proximal end of the thrombus; and
re-expanding the thrombectomy device into the thrombus.

18. The method of claim 9 , wherein the thrombectomy device includes a generally cylindrical structure having overlapping edges in a roll-up configuration, and wherein expanding the thrombectomy device includes unrolling the device.

Assignees

• Covidien Lp

Inventors

• Epstein Evan
• Brown Kenneth

Classifications

• A61B2017/22034

  for gripping the obstruction or the tissue part from inside · CPC title

• A61B2090/3966

  Radiopaque markers visible in an X-ray image · CPC title

• A61B90/39

  Markers, e.g. radio-opaque or breast lesions markers · CPC title

• A61B17/221 Primary

  Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)} · CPC title

• A61F2/82

  Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents (stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07) · CPC title