Sulfonylureas and related compounds and use of same
US-10538487-B2 · Jan 21, 2020 · US
US11040985B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11040985-B2 |
| Application number | US-201916513621-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 16, 2019 |
| Priority date | Jan 23, 2017 |
| Publication date | Jun 22, 2021 |
| Grant date | Jun 22, 2021 |
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The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
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The invention claimed is: 1. A compound of formula (Ib): or a pharmaceutically acceptable salt, solvate, or tautomer thereof, wherein: X 1 is O or S; R 1 is selected from the group consisting of wherein represents a single bond or a double bo…
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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