Chemical compounds as inhibitors of interleukin-1 activity

US11040985B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11040985-B2
Application numberUS-201916513621-A
CountryUS
Kind codeB2
Filing dateJul 16, 2019
Priority dateJan 23, 2017
Publication dateJun 22, 2021
Grant dateJun 22, 2021

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

First claim

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The invention claimed is: 1. A compound of formula (Ib): or a pharmaceutically acceptable salt, solvate, or tautomer thereof, wherein: X 1 is O or S; R 1 is selected from the group consisting of wherein represents a single bond or a double bo…

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What does patent US11040985B2 cover?
The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
Who is the assignee on this patent?
Genentech Inc
What technology area does this patent fall under?
Primary CPC classification C07D498/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).