Composition, pharmaceutical composition, use of a stable topical composition comprising a nanoemulsion and of at least one antileishmanial compound, and method for the treatment of cutaneous leishmaniasis
US-2024016826-A1 · Jan 18, 2024 · US
US11040935B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11040935-B2 |
| Application number | US-201716339534-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 4, 2017 |
| Priority date | Oct 5, 2016 |
| Publication date | Jun 22, 2021 |
| Grant date | Jun 22, 2021 |
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Described herein are compounds that disrupt the interaction between Fbxo48 and phosphorylated-AMPK.
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What is claimed is: 1. A compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof. 2. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 3. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 4. A compound of formula: or a pharmaceutically acceptable salt thereof.
having hydroxy groups, e.g. sphingosine · CPC title
Nitrogen atoms · CPC title
with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom · CPC title
having no double bonds between ring members or between ring members and non-ring members · CPC title
by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms · CPC title
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