Farnesoid X receptor modulators
US-10532061-B2 · Jan 14, 2020 · US
US11034717B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11034717-B2 |
| Application number | US-201615288390-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 7, 2016 |
| Priority date | Oct 7, 2015 |
| Publication date | Jun 15, 2021 |
| Grant date | Jun 15, 2021 |
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The present application provides a compound of formula I:or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1-R10, m, n, p, and are as described herein. The present invention relates generally to FXR modulators and to methods of making and using said compounds.
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The invention claimed is: 1. A compound selected from: or a pharmaceutically acceptable salt or solvate thereof. 2. A pharmaceutical composition comprising the compound of claim 1 or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable carrier or excipient. 3. The compound of claim 1 , which is or a pharmaceutically acceptable salt or solvate thereof. 4. The compound of claim 3 , which is or a pharmaceutically acceptable salt thereof. 5. The compound of claim 3 , which is 6. The compound of claim 1 , which is or a pharmaceutically acceptable salt or solvate thereof. 7. The compound of claim 6 , which is or a pharmaceutically acceptable salt thereof. 8. The compound of claim 6 , which is 9. A pharmaceutical composition comprising the compound of claim 3 or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable carrier or excipient. 10. A pharmaceutical composition comprising the compound of claim 6 or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable carrier or excipient.
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