Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection

US11034650B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11034650-B2
Application numberUS-201716472001-A
CountryUS
Kind codeB2
Filing dateDec 22, 2017
Priority dateDec 23, 2016
Publication dateJun 15, 2021
Grant dateJun 15, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

First claim

Opening claim text (preview).

The invention claimed is: 1. A compound according to formula A: or a stereoisomer, pharmaceutically acceptable salt thereof, wherein the compound is selected from the group consisting of No A L M 1 cyclopropylamine —CH 2 — meta phenyl 2 (CH 3 ) 2 CHNH— —CH 2 — meta phenyl 3 CH 2 CHCH 2 NH— —CH 2 — meta phenyl 4 (CH 3 ) 3 CCH 2 NH— —CH 2 — meta phenyl 5 CH 3 O(CH 2 ) 2 NH— —CH 2 — meta phenyl 6 (CH 3 ) 2 N(CH 2 ) 2 NH— —CH 2 — meta phenyl 7 CO 2 HCH 2 NH— —CH 2 — meta phenyl 8 (C 2 H 5 ) 2 N— —CH 2 — meta phenyl 9 morpholine —CH 2 — meta phenyl 10 4-tert-butyl-piperidine —CH 2 — meta phenyl 11 4-phenyl-piperidine —CH 2 — meta phenyl 12 4-phenyl-piperazine —CH 2 — meta phenyl 13 1-(pyridin-2-yl)-piperazine —CH 2 — meta phenyl 14 1,2,3,4-tetrahydro- —CH 2 — meta phenyl isoquinoline 15 heliamine —CH 2 — meta phenyl 16 benzylamine —CH 2 — meta phenyl 17 N-methylbenzylamine —CH 2 — meta phenyl 18 4-chlorobenzylamine —CH 2 — meta phenyl 19 4-methoxybenzylamine —CH 2 — meta phenyl 20 4-dimethylaminobenzylamine —CH 2 — meta phenyl 21 4-trifluoromethylbenzylamine —CH 2 — meta phenyl 22 4-pyridylmethanamine —CH 2 — meta phenyl 23 3,4-dimethylbenzylamine —CH 2 — meta phenyl 24 cyclopropylamine —CH 2 — meta phenyl 25 (CH 3 ) 2 CHNH— —CH 2 — meta phenyl 26 CH 2 CHCH 2 NH— —CH 2 — meta phenyl 27 (CH 3 ) 3 CCH 2 NH— —CH 2 — meta phenyl 28 CH 3 O(CH 2 ) 2 NH— —CH 2 — meta phenyl 29 (CH 3 ) 2 N(CH 2 ) 2 NH— —CH 2 — meta phenyl 30 CO 2 HCH 2 NH— —CH 2 — meta phenyl 31 (C 2 H 5 ) 2 N— —CH 2 — meta phenyl 32 morpholine —CH 2 — meta phenyl 33 1,1-dioxo-thiomorpholine —CH 2 — meta phenyl 34 4-tert-butyl-piperidine —CH 2 — meta phenyl 35 4-phenyl-piperidine —CH 2 — meta phenyl 36 4-phenyl-piperazine —CH 2 — meta phenyl 37 1-(pyridin-2-yl)-piperazine —CH 2 — meta phenyl 38 1,2,3,4-tetrahydro- —CH 2 — meta phenyl isoquinoline 39 heliamine —CH 2 — meta phenyl 40 benzylamine —CH 2 — meta phenyl 41 N-methylbenzylamine —CH 2 — meta phenyl 42 4-chlorobenzylamine —CH 2 — meta phenyl 43 4-methoxybenzylamine —CH 2 — meta phenyl 44 4-dimethylaminobenzylamine —CH 2 — meta phenyl 45 4-trifluoromethylbenzylamine —CH 2 — meta phenyl 46 4-pyridylmethanamine —CH 2 — meta phenyl 47 3,4-dimethylbenzylamine —CH 2 — meta phenyl 48 (CH 3 ) 2 CHNH— —CH 2 — meta phenyl 49 CH 2 CHCH 2 NH— —CH 2 — meta phenyl 50 (CH 3 ) 3 CCH 2 NH— —CH 2 — meta phenyl 51 CH 3 O(CH 2 ) 2 NH— —CH 2 — meta phenyl

Assignees

Inventors

Classifications

  • C07C259/06Primary

    having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms · CPC title

  • The ring being saturated · CPC title

  • Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

  • Drugs for disorders of the respiratory system · CPC title

  • Amides · CPC title

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Frequently asked questions

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What does patent US11034650B2 cover?
The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).
Who is the assignee on this patent?
Intervet Inc
What technology area does this patent fall under?
Primary CPC classification C07C259/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).