Cloud computing environment for biological data

Patent metadata

Field	Value
Publication number	US-11031132-B2
Application number	US-201916259434-A
Country	US
Kind code	B2
Filing date	Jan 28, 2019
Priority date	Apr 11, 2012
Publication date	Jun 8, 2021
Grant date	Jun 8, 2021

Abstract

The present invention provides a novel approach for storing, analyzing, and/or accessing biological data in a cloud computing environment. Sequence data generated by a particular sequencing device may be uploaded to the cloud computing environment during a sequencing run, which reduces the on-site storage needs for the sequence data. Analysis of the data may also be performed in the cloud computing environment, and the instructions for such analysis may be set at the originating sequencing device. The sequence data in the cloud computing environment may be shared according to permissions. Further, the sequence data may be modified or annotated by authorized secondary users.

First claim

The invention claimed is:

1. A computer implemented method in a cloud computing environment, comprising:
receiving, by at least one server, sequence data generated by a sequencing device performing sequencing runs, wherein the sequence data comprises base calls for nucleic acids of a biological sample;
receiving, by the at least one server, device diagnostic data comprising information about a number of the sequencing runs performed by the sequencing device;
storing, by the at least one server, the sequence data and the device diagnostic data in the cloud computing environment;
communicating, from the cloud computing environment, a message to a cloud access device of an authorized user of the sequencing device, the message being based on the sequencing runs in the received sequence data; and
communicating, from the cloud computing environment, the device diagnostic data to a manufacturer of the sequencing device, wherein the device diagnostic data is communicated separately from the sequence data.

2. The computer-implemented method of claim 1 , wherein the device diagnostic data further comprises information about a bug or error in the sequencing device.

3. The computer-implemented method of claim 1 , wherein the device diagnostic data further comprises information about a software update check.

4. The computer-implemented method of claim 3 , comprising determining that the sequencing device needs a software update and communicating the software update to the sequencing device.

5. The computer-implemented method of claim 1 , wherein the sequence data comprises quality data.

6. The computer-implemented method of claim 5 , wherein the message is further based on the quality data.

7. The computer-implemented method of claim 1 , wherein the authorized user is a laboratory facility.

8. The computer-implemented method of claim 1 , wherein the device diagnostic data does not comprise the sequence data.

Assignees

• Illumina Inc

Inventors

• Dickinson Alexander G
• Garcia Francisco Jose
• Kain Robert C
• Kahn Scott D
• Nelson Andrew R

Classifications

• G16B50/30

  Data warehousing; Computing architectures · CPC title

• G16B50/10

  Ontologies; Annotations · CPC title

• G16B30/10

  Sequence alignment; Homology search · CPC title

• G16H40/40

  for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades · CPC title

• H04L63/08

  for authentication of entities (cryptographic mechanisms or cryptographic arrangements for entity authentication H04L9/32) · CPC title