Drive screw device, liquid delivery mechanism, and liquid delivery method

Patent metadata

Field	Value
Publication number	US-11029281-B2
Application number	US-201616333258-A
Country	US
Kind code	B2
Filing date	Sep 23, 2016
Priority date	Sep 23, 2016
Publication date	Jun 8, 2021
Grant date	Jun 8, 2021

Abstract

This drive screw device is provided with: a drive screw; a drive unit which causes the drive screw to rotate; a slider which moves along the drive screw by means of the rotation of the drive screw; and an external load which is provided on the drive screw and applies a rotational load to the drive screw. By this means it is possible to provide a drive screw device with which there is little pressure variation even if a frictional force varies.

First claim

The invention claimed is:

1. A liquid delivery mechanism which feeds a phoretic medium in a container or a washing liquid to a capillary, the mechanism comprising:
a drive screw;
a motor configured to cause the drive screw to rotate;
a slider configured to move along the drive screw by means of a rotation of the drive screw; and
a mechanism which applies an external load drive screw and applies a rotational resistance to the drive screw independently of a frictional force of the drive screw,
wherein a plunger which presses the container toward the capillary is provided in the slider,
wherein the rotational resistance applied to the drive screw is larger than a force of a liquid delivery reaction, caused by an internal pressure of the container of the phoretic medium, for reversing the drive screw that is generated during feeding of the phoretic medium or the washing liquid, and
wherein the mechanism which applies the external load is a torque limiter which is formed by coaxially fitting an inner ring part and an outer ring part.

2. The liquid delivery mechanism according to claim 1 , wherein
the motor is a stepping motor.

3. The liquid delivery mechanism according to claim 1 , the mechanism further comprising:
a sensor configured to detect an origin position of the plunger.

4. The liquid delivery mechanism according to claim 1 , further comprising:
the motor is a stepping motor that is controlled to be stepped out and driven, the stepping motor being stepped out when the rotation of the drive screw stops, a constant pulse rate is provided to the stepping motor, but the stepping motor is not rotated by the pulse rate.

5. The liquid delivery mechanism according to claim 4 , further comprising:
a detection part which detects when the stepping motor is in a state of being stepped out.

6. The liquid delivery mechanism according to claim 1 , wherein
the inner ring part and the outer ring part are configured to be separately rotatable and a rotational resistance is provided therebetween.

7. The liquid delivery mechanism according to claim 6 , wherein
the rotational resistance is generated by magnetic force.

8. The liquid delivery mechanism according to claim 1 , wherein
the drive screw is a sliding screw or a ball screw.

9. The liquid delivery mechanism according to claim 1 , wherein
the drive screw and the inner ring part are configured to be rotatable synchronously, and
the outer ring part is fixed so as not to rotate.

10. A liquid delivery mechanism which feeds a phoretic medium in a container or a washing liquid to a capillary, the mechanism comprising:
a drive screw;
a motor configured to cause the drive screw to rotate;
a slider configured to move along the drive screw by means of a rotation of the drive screw; and
a mechanism which applies an external load drive screw and applies a rotational resistance to the drive screw independently of a frictional force of the drive screw,
wherein a plunger which presses the container toward the capillary is provided in the slider,
wherein the rotational resistance applied to the drive screw is larger than a force of a liquid delivery reaction, caused by an internal pressure of the container of the phoretic medium, for reversing the drive screw that is generated during feeding of the phoretic medium or the washing liquid, and
wherein the motor is configured to drive the motor in different states including a first state where a thrust of the plunger and the liquid delivery reaction are balanced, a second state where the external load and the liquid delivery reaction are balanced, and a third state where the liquid delivery reaction is larger than the thrust.

11. A liquid delivery mechanism which feeds a phoretic medium in a container or a washing liquid to a capillary, the mechanism comprising:
a drive screw;
a motor configured to cause the drive screw to rotate;
a slider configured to move along the drive screw by means of a rotation of the drive screw; and
a mechanism which applies an external load drive screw and applies a rotational resistance to the drive screw independently of a frictional force of the drive screw,
wherein a plunger which presses the container toward the capillary is provided in the slider,
wherein the rotational resistance applied to the drive screw is larger than a force of a liquid delivery reaction, caused by an internal pressure of the container of the phoretic medium, for reversing the drive screw that is generated during feeding of the phoretic medium or the washing liquid, and
wherein the plunger feeds the phoretic medium or the washing liquid to the capillary by pressing the container which is held on a sample tray from below.

12. A liquid delivery method which feeds a phoretic medium in a container or a washing liquid to a capillary by pressing the container by a plunger which is attached to a slider which moves along a drive screw by means of the rotation of the drive screw, wherein
a rotational resistance is applied as an external load to the drive screw independently of a frictional force of the drive screw, and
a rotational resistance generated by the external load is larger than a force of a liquid delivery reaction, caused by an internal pressure of the container of the phoretic medium, for reversing the drive screw that is generated during feeding of the phoretic medium or the washing liquid,
wherein the external load is applied by a torque limiter which is formed by coaxially fitting an inner ring part and an outer ring part.

13. The liquid delivery method according to claim 12 , wherein
a rotation of the drive screw is controlled such that a stepping motor is stepped out and driven, the stepping motor being stepped out when the rotation of the drive screw stops, a constant pulse rate is provided to the stepping motor, but the stepping motor is not rotated by the pulse rate.

14. A liquid delivery method which feeds a phoretic medium in a container or a washing liquid to a capillary by pressing the container by a plunger which is attached to a slider which moves along a drive screw by means of the rotation of the drive screw, wherein
a rotational resistance is applied as an external load to the drive screw independently of a frictional force of the drive screw, and
a rotational resistance generated by the external load is larger than a force of a liquid delivery reaction, caused by an internal pressure of the container of the phoretic medium, for reversing the drive screw that is generated during feeding of the phoretic medium or the washing liquid,
wherein the drive screw is driven in different states including a first state where a thrust of the plunger and a liquid delivery reaction are balanced, a second state where the external load and the liquid delivery reaction are balanced, and a third state where the liquid delivery reaction is larger than the thrust.

Assignees

• Hitachi High Tech Corp

Inventors

• Aritome Katsuhiro
• Kimura Ryusuke
• Yamazaki Motohiro
• Nakajima Go
• Kawasaki Naomichi

Classifications

• G01N27/44782 Primary

  of a plurality of samples · CPC title

• G01N27/447 Primary

  using electrophoresis · CPC title

• B05C7/08

  for applying liquids or other fluent materials to the inside of tubes · CPC title

• G01N27/44756

  Apparatus specially adapted therefor · CPC title

• G01N27/44743

  Introducing samples · CPC title