Nrf2 regulators
US-10604509-B2 · Mar 31, 2020 · US
US11028099B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11028099-B2 |
| Application number | US-201716469203-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 11, 2017 |
| Priority date | Dec 15, 2016 |
| Publication date | Jun 8, 2021 |
| Grant date | Jun 8, 2021 |
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The present invention relates to a compound which is (R)-3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-2-ethyl-2,3-dihydropyrido[2,3-f][1,4]oxazepin-4(5H)-yl)methyl)-4-methylphenyl)propanoic acid (I), or a pharmaceutically acceptable salt thereof, in particular, the meglumine salt thereof, a pharmaceutical composition containing the compound and its use as an NRF2 activator.
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What is claimed is: 1. A compound which is (R)-3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-2-ethyl-2,3-dihydropyrido[2,3-f][1,4]oxazepin-4(5H)-yl)methyl)-4-methylphenyl)propanoic acid: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising the compound of claim 1 and one or more pharmaceutically acceptable excipients.
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