Traditional Chinese medicine composition and use thereof

Patent metadata

Field	Value
Publication number	US-11026988-B2
Application number	US-201816058484-A
Country	US
Kind code	B2
Filing date	Aug 8, 2018
Priority date	Sep 7, 2017
Publication date	Jun 8, 2021
Grant date	Jun 8, 2021

Abstract

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

First claim

What is claimed is:

1. A method of inhibiting the growth of tumor, increasing the percentage of CD 4 + and CD 8 + cells in lymphocytes of tumor stroma, decreasing VEGF and TGF-β1 positive cells in tumor tissue, enhancing immunity, preventing and/or assisting in treating tumor, and/or restoring normal immune function, comprising administrating an effective amount of a traditional Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition consists of Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil; and
the weight ratio of Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil is (1 to 5):(1 to 5):(1 to 5):(1 to 5).

2. The method according to claim 1 , wherein the weight ratio of Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil is (1 to 2):(1 to 2):(1 to 2):(1 to 2).

3. The method according to claim 1 , wherein the weight ratio of Lycii fructus polysaccharide, Polygonati rhizoma polysaccharide, Caryophylli flos oil and Cinnamomi cortex oil is 1:1:1.5: 1.5.

4. The method according to claim 1 , wherein the Chinese medicine composition is in the form of a health food or a medicine.

5. The method according to claim 4 , wherein the health food or the medicine further comprises a pharmaceutically acceptable excipient or a food acceptable excipient.

Assignees

• Infinitus China Co Ltd

Inventors

• Ma Fangli
• Wang Yuanyuan
• Hu Minghua
• Cong Renhuai
• Xiao Lingyun
• Ma Chung Wah

Classifications

• A23L33/115

  Fatty acids or derivatives thereof; Fats or oils · CPC title

• A23L33/105

  Plant extracts, their artificial duplicates or their derivatives · CPC title

• A61K36/61 Primary

  Myrtaceae (Myrtle family), e.g. teatree or eucalyptus · CPC title

• A23L33/12

  Fatty acids or derivatives thereof · CPC title

• A61K2236/39

  Complex extraction schemes, e.g. fractionation or repeated extraction steps · CPC title