Methods and compositions for treating mesothelioma and small lung cancer that express midkine

US11026950B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11026950-B2
Application numberUS-202016857285-A
CountryUS
Kind codeB2
Filing dateApr 24, 2020
Priority dateJul 28, 2016
Publication dateJun 8, 2021
Grant dateJun 8, 2021

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  1. Title

    What the patent document calls the invention.

  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Embodiments provided herein relate to methods and compositions for treating mesothelioma and/or a small cell lung cancer that express midkine.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating malignant mesothelioma, comprising the step of administering to an individual in need thereof, an effective amount of a pharmaceutical composition comprising a compound selected from or a pharmaceutically acceptable salt thereof, and a pharmaceutical carrier. 2. The method of claim 1 , wherein said compound is: or a pharmaceutically acceptable salt thereof. 3. The method of claim 1 , wherein the compound is administered with 4. The method of claim 1 , further comprising the step of administering to said individual a therapeutically effective amount of a BCL-2 inhibitor. 5. The method of claim 1 , wherein said individual is mammalian. 6. The method of claim 1 , wherein said individual is human. 7. The method of claim 4 , wherein said BCL-2 inhibitor is selected from ABT-737, ABT-199, GDC-0199, GX15-070 (Obatoclax), and combinations thereof.

Assignees

Inventors

Classifications

  • containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone · CPC title

  • Antineoplastic agents · CPC title

  • not condensed and containing further heterocyclic rings, e.g. timolol · CPC title

  • containing further heterocyclic ring systems · CPC title

  • the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine · CPC title

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Frequently asked questions

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What does patent US11026950B2 cover?
Embodiments provided herein relate to methods and compositions for treating mesothelioma and/or a small cell lung cancer that express midkine.
Who is the assignee on this patent?
Childrens Hospital Med Ct
What technology area does this patent fall under?
Primary CPC classification A61K31/5377. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 08 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 4 related publications on this page (citations in our corpus or others sharing the same primary CPC).