Method and apparatus for cardiac procedures

Patent metadata

Field	Value
Publication number	US-11026672-B2
Application number	US-201816012195-A
Country	US
Kind code	B2
Filing date	Jun 19, 2018
Priority date	Jun 19, 2017
Publication date	Jun 8, 2021
Grant date	Jun 8, 2021

Abstract

Described herein are methods and apparatus for approximating targeted tissue by intertwining two or more sutures together. The sutures are attached to the targeted tissue and routed to a twister device. The twister device secures end portions of the sutures and twists them to intertwine the sutures. Controlling the number of twists provides control over the forces applied to the targeted tissue. In conjunction with visualization feedback, real-time adjustments can be made to achieved targeted results, such as elimination of mitral regurgitation when the disclosed methods and apparatus are applied to mitral valve repair.

First claim

What is claimed is:

1. A method for twisting sutures together to approximate anchor implants attached to targeted tissue, the method comprising:
attaching two or more cords to targeted tissue, each of the two or more cords including a distal anchor implant and a suture extending proximally from the distal anchor implant;
securing proximal end portions of the sutures of the two or more cords to a twister device;
operating the twister device to cause the sutures of the two or more cords to intertwine;
releasing the proximal end portions of the sutures of the two or more cords from the twister device; and
anchoring the proximal end portions of the sutures of the two or more cords to prevent unwinding of the sutures of the two or more cords.

2. The method of claim 1 , wherein the targeted tissue is within the heart and the twister device is positioned outside of the heart so that it is operated outside of the heart.

3. The method of claim 2 , wherein anchoring the proximal end portions of the sutures of the two or more cords includes securing the proximal end portions to an external wall of the heart.

4. The method of claim 2 further comprising inserting a portion of the twister device into a valve introducer that provides access to the targeted tissue within the heart.

5. The method of claim 1 , wherein the targeted tissue includes a leaflet of a mitral valve.

6. The method of claim 5 , wherein the targeted tissue includes a posterior leaflet.

7. The method of claim 5 , wherein the targeted tissue includes an anterior leaflet.

8. The method of claim 1 further comprising adjusting a tension of the sutures of the two or more cords.

9. The method of claim 8 , wherein adjusting a tension of the sutures of the two or more cords occurs simultaneously with operating the twister device to cause the sutures of the two or more cords to intertwine.

10. The method of claim 1 , wherein operating the twister device to cause the sutures of the two or more cords to intertwine results in a point of intersection that approaches the targeted tissue to change a force vector on the two or more cords attached to the targeted tissue.

11. The method of claim 1 , wherein the distal anchors of the two or more cords are secured to tissue within a heart and the proximal end portions of the sutures of the two or more cords are anchored to an external wall of the heart.

12. The method of claim 11 , wherein a portion of the twister device to which the proximal end portions of the sutures of the two or more cords are secured is located outside of the heart.

13. The method of claim 1 , wherein the targeted tissue is within a heart so that the distal anchor implants of the two or more cords are attached to the targeted tissue within the heart and the proximal end portions of the sutures extend outside of the heart.

14. The method of claim 1 , wherein operating the twister device to cause the sutures of the two or more cords to intertwine improves coaptation of a mitral valve.

15. The method of claim 1 , wherein attaching two or more cords to targeted tissue includes deploying each of the distal anchor implants of the two or more cords on a distal side of the targeted tissue with each of the sutures of the two or more cords passing through the targeted tissue to extend proximally from the targeted tissue.

16. The method of claim 1 , wherein anchoring includes tying one or more knots in the proximal end portions of the two or more cords to secure the proximal end portions to anchor tissue.

17. The method of claim 1 , wherein anchoring includes securing the proximal end portions of the two or more cords to maintain an axial force on each of the sutures of the two or more cords.

18. The method of claim 17 , wherein the axial force is directed proximally from the distal anchor implants of the two or more cords.

19. The method of claim 17 , wherein the axial force pulls the distal anchor implants of the two or more cords proximally and toward each other.

Assignees

• Harpoon Medical Inc
• Univ Maryland

Inventors

• Niland William
• Cortez Jr Felino V
• Gammie James S
• D'Ambra Michael Nicholas
• Wilson Peter
• Cournane Stephen

Classifications

• A61F2/2457 Primary

  Chordae tendineae prostheses · CPC title

• A61B17/0483

  Hand-held instruments for holding sutures (A61B17/0469 takes precedence; other holders for needles or sutures A61B17/06061; surgical forceps A61B17/28; surgical pincettes A61B17/30) · CPC title

• A61B2017/3425

  for internal organs, e.g. heart ports · CPC title

• A61F2/2466

  Delivery devices therefor · CPC title

• A61B17/0485

  Devices or means, e.g. loops, for capturing the suture thread and threading it through an opening of a suturing instrument or needle eyelet · CPC title