Filaments comprising an ingestible active agent nonwoven webs and methods for making same

Patent metadata

Field	Value
Publication number	US-11021812-B2
Application number	US-201113229818-A
Country	US
Kind code	B2
Filing date	Sep 12, 2011
Priority date	Jul 2, 2010
Publication date	Jun 1, 2021
Grant date	Jun 1, 2021

Abstract

Filaments containing a filament-forming material and an additive, such as an ingestible active agent, nonwoven webs, and methods for making such filaments are provided.

First claim

What is claimed is:

1. A nonwoven web comprising a plurality of inter-entangled filaments and one or more particulate active agents wherein at least one of the one or more particulate active agents is separate from the filaments, wherein the plurality of inter-entangled filaments exhibits lengths greater than or equal to 5.08 cm and comprises one or more filament-forming materials and one or more tooth care active agents that are releasable from the plurality of inter-entangled filaments upon dissolution in water, wherein the total level of the one or more filament-forming materials present in the plurality of inter-entangled filaments is less than 40% by weight on a dry filament basis and the total level of the one or more active agents present in the plurality of inter-entangled filaments is at least 60% by weight on a dry filament basis and wherein the plurality of inter-entangled filaments exhibits diameters of greater than 1 μm as measured according to the Diameter Test Method.

2. The nonwoven web according to claim 1 wherein the total level of the one or more tooth care active agents present in the plurality of inter-entangled filaments is at least 65% by weight on a dry filament basis.

3. The nonwoven web according to claim 1 wherein the one or more filament-forming materials and the one or more tooth care active agents are present in the plurality of inter-entangled filaments at a weight ratio of filament-forming materials to ingestible active agents of less than 4.0.

4. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments exhibits a water content of less than 20% as measured according to the Water Content Test Method.

5. The nonwoven web according to claim 1 wherein the one or more filament-forming materials comprises a polar solvent-soluble material.

6. The nonwoven web according to claim 5 wherein the polar solvent-soluble material comprises a water-soluble material.

7. The nonwoven web according to claim 5 wherein the polar solvent-soluble material comprises an alcohol-soluble material.

8. The nonwoven web according to claim 1 wherein the one or more filament-forming materials comprises a non-polar solvent-soluble material.

9. The nonwoven web according to claim 1 wherein the one or more filament-forming materials comprises a sugar.

10. The nonwoven web according to claim 1 wherein the one or more filament-forming materials comprises a polymer.

11. The nonwoven web according to claim 10 wherein the polymer comprises a non-thermoplastic polymer.

12. The nonwoven web according to claim 10 wherein the polymer is selected from the group consisting of: pullulan, hydroxypropylmethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, polyvinyl pyrrolidone, carboxymethyl cellulose, sodium alginate, xanthan gum, tragacanth gum, guar gum, acacia gum, Arabic gum, polyacrylic acid, methylmethacrylate copolymer, carboxyvinyl polymer, dextrin, pectin, chitin, levan, elsinan, collagen, gelatin, zein, gluten, soy protein, casein, polyvinyl alcohol, starch, starch derivatives, hemicellulose, hemicellulose derivatives, proteins, chitosan, chitosan derivatives, polyethylene glycol, tetramethylene ether glycol, hydroxymethyl cellulose, and mixtures thereof.

13. The nonwoven web according to claim 10 wherein the polymer comprises polyvinyl alcohol.

14. The nonwoven web according to claim 10 wherein the polymer comprises starch or starch derivative.

15. The nonwoven web according to claim 10 wherein the polymer exhibits a weight average molecular weight of greater than about 10,000 g/mol.

16. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments further comprises a flavoring agent.

17. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments further comprises a sweetener.

18. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments further comprises a cooling agent.

19. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments exhibits diameters of less than 50 μm as measured according to the Diameter Test Method.

20. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments comprises two or more different filament-forming materials.

21. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments comprises two or more different active agents.

22. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments further comprises a coating composition present on an external surface of the plurality of inter-entangled filaments.

23. The nonwoven web according to claim 22 wherein the coating composition comprises one or more active agents.

24. The nonwoven web according to claim 23 wherein at least one of the one or more active agents present in the coating composition is different from at least one of the one or more tooth care active agents present in the plurality of inter-entangled filaments.

25. A film produced from the nonwoven web according to claim 1 .

26. The nonwoven web according to claim 1 wherein the plurality of inter-entangled filaments exhibits a water content of from 0% to about 20% as measured according to the Water Content Test Method.

27. The nonwoven web according to claim 26 wherein the plurality of inter-entangled filaments exhibits a water content of greater than 0% to less than 15% as measured according to the Water Content Test Method.

Assignees

• Gordon Gregory Charles
• Glenn Jr Robert Wayne
• Sivik Mark Robert
• Richards Mark Ryan
• Heinzman Stephen Wayne
• James Michael David
• Reynolds Geoffrey William
• Trokhan Paul Dennis
• Weisman Paul Thomas
• Gilbert Steven Ray
• Darcy Trevor John
• Procter & Gamble

Inventors

• Gordon Gregory Charles
• Glenn Jr Robert Wayne
• Sivik Mark Robert
• Richards Mark Ryan
• Heinzman Stephen Wayne
• James Michael David
• Reynolds Geoffrey William
• Trokhan Paul Dennis
• Weisman Paul Thomas
• Gilbert Steven Ray
• Darcy Trevor John

Classifications

• D01H1/00

  Spinning or twisting machines in which the product is wound-up continuously (open-end spinning machines D01H4/00 {; doubling of yarns B65H54/00+T; doubled, plied or cabled threads D02G3/28, e.g. using hollow spindles D02G3/283; spin-twisting D02G3/281; threads with alternately "S" and "Z" direction of twist, e.g. self-twist process, D02G3/286; wrapping strands of filaments or staple fibres by a binder yarn D02G3/38}) · CPC title

• A61K47/36

  Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin · CPC title

• A61K9/70

  Web, sheet or filament bases {; Films; Fibres of the matrix type containing drug (hollow drug-filled fibres A61K9/0092)} · CPC title

• A61K47/30 Primary

  Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates · CPC title

• D04H3/00

  Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length · CPC title