Carbamate compounds and methods of making and using same
US-2018208568-A1 · Jul 26, 2018 · US
US11021453B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11021453-B2 |
| Application number | US-201916717813-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 17, 2019 |
| Priority date | Jan 6, 2012 |
| Publication date | Jun 1, 2021 |
| Grant date | Jun 1, 2021 |
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This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for a method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition.
Opening claim text (preview).
What is claimed is: 1. A method of treating post-traumatic stress disorder in a patient in need thereof, comprising administering to the patient an effective amount of 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate, or a pharmaceutically acceptable salt thereof.
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