Pyrroloquinolin compounds and methods of using same

US11020488B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11020488-B2
Application numberUS-201816493690-A
CountryUS
Kind codeB2
Filing dateMar 13, 2018
Priority dateMar 14, 2017
Publication dateJun 1, 2021
Grant dateJun 1, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Provided are pyrroloquinolin compounds of formula (1) or (II). In certain aspects, the pyrroloquinolin compounds are therapeutic, e.g., for treating a cell proliferative disorder. Also provided are conjugates that include the pyrroloquinolin compounds of the present disclosure. Compositions, e.g., pharmaceutical compositions, that include the pyrroloquinolin compounds and conjugates of the present disclosure are also provided. Further provided are therapeutic methods involving the administration of the pyrroloquinolin compounds, conjugates or compositions of the present disclosure. Kits that include the pyrroloquinolin compounds, conjugates or compositions are also provided.

First claim

Opening claim text (preview).

What is claimed is: 1. A compound selected from the group consisting of: 2. A pharmaceutical composition, comprising: the compound of claim 1 ; and a pharmaceutically acceptable carrier.

Assignees

Inventors

Classifications

  • C07D471/06Primary

    Peri-condensed systems · CPC title

  • the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline · CPC title

  • Antineoplastic agents · CPC title

  • Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates · CPC title

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What does patent US11020488B2 cover?
Provided are pyrroloquinolin compounds of formula (1) or (II). In certain aspects, the pyrroloquinolin compounds are therapeutic, e.g., for treating a cell proliferative disorder. Also provided are conjugates that include the pyrroloquinolin compounds of the present disclosure. Compositions, e.g., pharmaceutical compositions, that include the pyrroloquinolin compounds and conjugates of the pres…
Who is the assignee on this patent?
Univ California, Ford Henry Health System
What technology area does this patent fall under?
Primary CPC classification C07D471/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).