Sensor, cartridge and drug delivery device

Patent metadata

Field	Value
Publication number	US-11007322-B2
Application number	US-201615748898-A
Country	US
Kind code	B2
Filing date	Jul 26, 2016
Priority date	Jul 31, 2015
Publication date	May 18, 2021
Grant date	May 18, 2021

Abstract

In one aspect, the present disclosure relates to a sensor for measuring at least one physical or chemical parameter of a cartridge or syringe filled with a liquid substance. In further aspects the disclosure relates to a cartridge equipped with such a sensor and a drug delivery device equipped with such a cartridge. The sensor comprises a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge or syringe. The sensor also includes at least a first and a second measuring electrode is arranged on the foil and at least a first and a second contact electrode is arranged on the foil. The sensor further comprises, processor connected to the first and to the second measurement electrodes and a transceiver arranged on the foil. The transceiver is also and connected to the processor. Additionally, the first contact electrode and the second contact electrode are connected to the processor.

First claim

The invention claimed is:

1. A sensor for measuring at least one physical or chemical parameter of a cartridge or syringe filled with a liquid substance, the sensor comprising:
a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge or syringe;
at least a first measuring electrode and a second measuring electrode each arranged and fixed on the planar flexible foil, the first measuring electrode and the second measuring electrode configured to measure electrical capacity;
at least a first contact electrode and a second contact electrode each arranged and fixed on the planar flexible foil, the first contact electrode and the second contact electrode configured to provide an electrical contact to an external electric energy supply;
a processor arranged on the planar flexible foil and connected to the first measurement electrode and the second measurement electrode; and
a transceiver arranged on the planar flexible foil and connected to the processor,
wherein the first contact electrode and the second contact electrode are connected to the processor and configured to provide electric energy from the external electric energy supply through the first contact electrode and the second contact electrode to the processor when the first contact electrode and the second contact electrode are in contact with the external electric energy supply.

2. The sensor according to claim 1 , wherein the first contact electrode and the second contact electrode are arranged at a longitudinal end section of the planar flexible foil.

3. The sensor according to claim 1 , wherein the first contact electrode and the second contact electrode are separated in a longitudinal direction and extend substantially parallel in a lateral or circumferential direction.

4. The sensor according to claim 1 , wherein the planar flexible foil has a lateral dimension and wherein first contact electrode and the second contact electrode extend across substantially the entire lateral dimension of the planar flexible foil.

5. The sensor according to claim 1 , wherein the planar flexible foil is substantially transparent and wherein at least one of the first measuring electrode and the second measuring electrode comprise a printed or coated conductive structure on or in the planar flexible foil.

6. The sensor according to claim 1 , wherein the planar flexible foil is substantially transparent and wherein at least one of the first contact electrode and the second contact electrode comprise a printed or coated conductive structure on or in the planar flexible foil.

7. The sensor according to claim 1 , wherein the first measuring electrode and the second measuring electrode and the first contact electrode and the second contact electrode are located on a common side of the planar flexible foil.

8. The sensor according to claim 1 , wherein the first measuring electrode and the second measuring electrode and the first contact electrode and the second contact electrode are located on opposite sides of the planar flexible foil.

9. The sensor according to claim 1 , wherein the transceiver is configured to withdraw and obtain electrical energy from an external RF field, and provide electrical energy to at least the processor.

10. The sensor according to claim 1 , wherein at least one of the first measurement electrode and the second measurement electrode is fixed and arranged on the planar flexible foil by way of printing or coating a conductive structure on the planar flexible foil.

11. The sensor according to claim 1 , wherein the first contact electrode and the second contact electrode connected to the processor are further configured to contact a first contact element and a second contact element within a housing, the housing being configured to accommodate the cartridge.

12. The sensor according to claim 1 , wherein the first measuring electrode and the second measuring electrode are configured to measure electrical capacity of a medium located between the first measuring electrode and the second measuring electrode.

13. A cartridge comprising a tubular shaped barrel filled with a liquid substance and comprising a sensor, the sensor comprising:
a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge or syringe;
at least a first measuring electrode and a second measuring electrode each arranged and fixed on the planar flexible foil, the first measuring electrode and the second measuring electrode configured to measure electrical capacity;
at least a first contact electrode and a second contact electrode each arranged and fixed on the planar flexible foil, the first contact electrode and the second contact electrode configured to provide an electrical contact to an external electric energy supply;
a processor arranged on the planar flexible foil and connected to the first measurement electrode and to the second measurement electrode; and
a transceiver arranged on the planar flexible foil and connected to the processor,
wherein the first contact electrode and the second contact electrode are connected to the processor and configured to provide electric energy from the external electric energy supply through the first contact electrode and the second contact electrode to the processor when the first contact electrode and the second contact electrode are in contact with the external electric energy supply, and
wherein the sensor is wrapped around the outer circumference of a sidewall of the barrel.

14. The cartridge according to claim 13 , wherein the sensor is adhesively attached to the barrel of the cartridge.

15. The cartridge according to claim 13 , wherein the first contact electrode and the second contact electrode of the sensor are located on an outward facing side of the planar flexible foil.

16. The cartridge according to claim 13 , wherein the liquid substance comprises a medicament.

17. A drug delivery device for administering a dose of a liquid medicament, comprising:
a housing to accommodate a cartridge with a tubular shaped barrel filled with the liquid medicament, wherein the cartridge comprises a piston slidably received in the barrel and comprises a sensor, the sensor comprising
a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge;
at least a first measuring electrode and a second measuring electrode each arranged and fixed on the planar flexible foil, the first measuring electrode and the second measuring electrode configured to measure electrical capacity;
at least a first contact electrode and a second contact electrode each arranged and fixed on the planar flexible foil, the first contact electrode and the second contact electrode being configured to provide an electrical contact to an external electric energy supply;
a processor arranged on the planar flexible foil and connected to the first measurement electrode and to the second measurement electrode; and
a transceiver arranged on the planar flexible foil and connected to the processor,
wherein the first contact electrode and the second contact electrode are connected to the processor and configured to provide electric energy from the external electric energy supply through the first contact electrode and the second contact electrode to the processor when the first contact electrode and the second contact electrode are in contact with the external electric energy supply,
wherein the sensor is wrapped around the outer circumference of a sidewall of the barrel;

a drive mechanism to exert a distally directed driving force on the piston for expelling

Assignees

• Sanofi Aventis Deutschland

Inventors

• Schabbach Michael
• Nessel Christian
• Auernhammer Daniel
• Soares Francisco
• Franke Beate

Classifications

• G01F23/263

  by measuring variations in capacitance of capacitors · CPC title

• A61M5/1684

  by detecting the amount of infusate remaining, e.g. signalling end of infusion · CPC title

• A61M2205/3317

  Electromagnetic, inductive or dielectric measuring means · CPC title

• A61M5/1452

  pressurised by means of pistons · CPC title

• A61M5/24 Primary

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title