Method for treating joint pain and associated instruments

Patent metadata

Field	Value
Publication number	US-11006992-B2
Application number	US-201816229737-A
Country	US
Kind code	B2
Filing date	Dec 21, 2018
Priority date	Nov 20, 2009
Publication date	May 18, 2021
Grant date	May 18, 2021

Abstract

The embodiments provide provides devices, instruments, and associated methods for treating joint pain. A joint is evaluated using magnetic resonance imaging to detect any defects in the subchondral bone. For example, using T2-weighted MRI images, bone marrow lesions or edemas can be identified, and using T1-weighted MRI images, associated regions of sclerotic bone adjacent to the bone marrow lesion can be identified. The treatment method may involve introducing a bone void filler material at the site to address the bone marrow lesion or edema, and/or drilling and inserting an implant to address the sclerotic bone, bone marrow lesion or edema, and insufficiency or stress fractures. An access path is mapped to a location in the subchondral region where the insufficiency fracture resides. The access path attempts to preserve an articular surface of the joint. A reinforcing member that stabilizes the insufficiency fracture is then implanted via the access path.

First claim

What is claimed is:

1. A method of accessing a targeted site in a subchondral region of a first bone adjacent a knee joint, the method comprising:
identifying a bone marrow lesion that is less than 10 cm from a knee joint through use of magnetic resonance imaging (MRI) of the knee joint, the bone marrow lesion occurring in a subchondral region of a first bone adjacent the knee joint, the subchondral region occurring under an articular surface of the first bone;
locating a guide instrument adjacent the first bone, the guide instrument including a probe, the probe including an elongate portion and a tip, wherein said locating includes contacting a location on the articular surface of the first bone with the tip of the probe to establish a targeted site in the subchondral region of the first bone in and/or adjacent to where the bone marrow lesion was identified, the targeted site spaced a distance from the tip of the probe; and
advancing an access tool through a first opening in the guide instrument and into the first bone, wherein the first opening guides the access tool to the targeted site in a first direction and in a manner that preserves an existing condition of the articular surface of the first bone, the first direction angled acutely relative to the elongate portion of the probe.

2. The method of claim 1 further comprising injecting an injectable fluid material into the targeted site.

3. The method of claim 2 , wherein the injectable fluid material is left in the targeted site for becoming less fluid in the targeted site for reinforcing bone located in the targeted site.

4. The method of claim 2 , wherein the injectable fluid material is left in the targeted site without also delivering and leaving a solid structural implant in the targeted site in addition to the injectable fluid material.

5. The method of claim 1 , wherein the targeted site is in where the bone marrow lesion was identified.

6. The method of claim 1 , wherein the targeted site is in and adjacent to where the bone marrow lesion was identified.

7. The method of claim 1 , wherein the targeted site is up to 5 cm from where the bone marrow lesion was identified.

8. The method of claim 1 , wherein the guide instrument is adjustable to allow for angular adjustment of the elongate portion of the probe relative to the first direction.

9. The method of claim 8 , wherein the guide instrument includes a curved body section.

10. The method of claim 9 , wherein the curved body section is connected to a second portion of the guide instrument through a sliding arrangement.

11. The method of claim 10 further comprising delivering bone marrow to the targeted site.

12. The method of claim 1 , wherein the targeted site is within 5 mm from the tip of the probe.

13. The method of claim 1 further comprising delivering an osteogenic material to the targeted site.

14. The method of claim 1 further comprising delivering bone marrow to the targeted site.

15. The method of claim 1 ; wherein the bone marrow lesion is less than 5 cm from the knee joint.

16. The method of claim 1 , wherein the bone marrow lesion is in a proximal tibia.

17. The method of claim 1 , herein the bone marrow lesion is in a distal femur.

18. A method of accessing a targeted site in a subchondral region of a first bone adjacent a knee joint, the method comprising:
identifying a bone marrow lesion in a subchondral region of a first bone adjacent a knee joint, the subchondral region occurring under an articular surface of the first bone;
locating a guide instrument adjacent the first bone with a tip of a probe of the guide instrument positioned to indicate a selected landmark on the first bone and with a first opening in the guide instrument being in receipt of an access tool that is advanceable through the first opening for entry into the first bone, wherein the tip of the probe being positioned to indicate the selected landmark on the first bone establishes a targeted site in the subchondral region of the first bone in and/or adjacent to where the bone marrow lesion was identified, the targeted site spaced a distance from the tip of the probe; and
advancing the access tool through the first opening and into the first bone, wherein the first opening guides the access tool to the targeted site in a first direction and in a manner that preserves an existing condition of the articular surface of the first bone.

19. The method of claim 18 further comprising injecting an injectable material into the targeted site.

20. The method of claim 19 , wherein the injectable material is left in the targeted site without also delivering and leaving a solid structural implant in the targeted site in addition to the injectable material.

21. The method of claim 18 , wherein the bone marrow lesion is less than 5 cm from the knee joint.

22. The method of claim 18 , wherein the bone marrow lesion is in a proximal tibia.

23. The method of claim 18 , wherein the bone marrow lesion is in a distal femur.

24. The method of claim 18 , wherein the targeted site is in and adjacent to where the bone marrow lesion was identified.

25. The method of claim 18 further comprising delivering bone marrow to the targeted site.

26. The method of claim 18 , wherein the probe includes a elongate portion that is angled acutely relative to the first direction.

Assignees

• Zimmer Knee Creations Inc

Inventors

• Sharkey Peter F
• Leinberry Charles F
• Cohen Steven B
• Bagga Charanpreet S
• Erbe Erik M

Classifications

• A61B17/1764 Primary

  for the knee · CPC title

• A61B17/90

  Guides therefor · CPC title

• A61B17/8872

  Instruments for putting said fixation devices against or away from the bone (A61B17/7074, A61B17/808 take precedence) · CPC title

• A61B17/1775

  for the foot or ankle · CPC title

• A61B17/68

  Internal fixation devices {, including fasteners and spinal fixators, even if a part thereof projects from the skin (bone staples A61B17/0642)} · CPC title