Method for producing carboxylic acid and alcohol by hydrolysis of ester
US-9206107-B2 · Dec 8, 2015 · US
Synthesis and use of ω-hydroxylated polyunsaturated fatty acids
US11001783B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11001783-B2 |
| Application number | US-202016867237-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 5, 2020 |
| Priority date | Aug 16, 2016 |
| Publication date | May 11, 2021 |
| Grant date | May 11, 2021 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treating cancer or macular degeneration, the method comprising administering to a subject in need thereof an effective amount of a ω-hydroxylated polyunsaturated fatty acid, or an ester form thereof, or a pharmaceutical composition thereof, wherein the ω-hydroxylated polyunsaturated fatty acid is selected from the group consisting of 20-HEPE, 22-HdoHE, or mixtures thereof. 2. The method of claim 1 wherein the ω-hydroxylated polyunsaturated fatty acid inhibits tumor growth, angiogenesis, lymphangiogenesis, or combinations thereof.
Assignees
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Classifications
Antineoplastic agents · CPC title
by increase in the number of carbon atoms · CPC title
- C07C51/09Primary
from carboxylic acid esters or lactones · CPC title
by isomerisation {(isomerisation induced by hydrogenation C11C3/12)} · CPC title
by hydrogenation of unsaturated carbon-to-carbon bonds · CPC title
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- What does patent US11001783B2 cover?
- The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.
- Who is the assignee on this patent?
- Univ California, Univ Massachusetts
- What technology area does this patent fall under?
- Primary CPC classification C07C51/09. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).