Apparatus and method for generating dialysate for dialysis

Patent metadata

Field	Value
Publication number	US-11000642-B2
Application number	US-201716316510-A
Country	US
Kind code	B2
Filing date	Jul 24, 2017
Priority date	Jul 22, 2016
Publication date	May 11, 2021
Grant date	May 11, 2021

Abstract

An apparatus for generating dialysate for dialysis comprising a dialysate outlet and a dialysate inlet and dialysate purifying means, wherein the purifying means comprise a cryopurifier for generating pure water, wherein the inlet of the cryopurifier is connected to the dialysate outlet and the outlet of the cryopurifier is connected to the dialysate inlet; and a method for reclaiming of fresh dialysate from ultrafiltrate and wasted dialysate extracted from a dialysis patient, comprising the following steps: preparing an ice slurry from the dialysate, wherein the ice slurry contains ice crystals and a liquid containing solutes; and separating the ice crystals from the liquid containing the solutes.

First claim

The invention claimed is:

1. An apparatus for generating dialysate for dialysis comprising:
a dialysate outlet;

a dialysate inlet; and
a cryopurifier for generating pure water, wherein an inlet of the cryopurifier is connected to the dialysate outlet and an outlet of the cryopurifier is connected to the dialysate inlet.

2. The apparatus according to claim 1 , wherein the cryopurifier comprises an ice crystal growth container and a wash column.

3. The apparatus according to claim 1 , wherein the outlet of the cryopurifier comprises a pure water outlet connected to the dialysate inlet.

4. The apparatus according to claim 1 , further comprising a dialysate prepurifier provided between the dialysate outlet and the cryopurifier inlet.

5. The apparatus according to claim 1 , further comprising a dialysate postpurifier provided between the cryopurifier outlet and the dialysate inlet.

6. The apparatus according to claim 1 , further comprising a heat exchanger for providing heat exchange between the cryopurifier inlet and a heater at the cryopurifier outlet.

7. The apparatus according to claim 1 , further comprising a base station and a wearable unit.

8. The apparatus according to claim 7 , wherein the cryopurifier is integrated in the wearable unit.

9. The apparatus according to claim 7 , further comprising a docking interface for connecting the base station with the wearable unit.

10. The apparatus according to claim 1 , wherein the dialysate inlet comprises an inlet of a dialyzer and the dialysate outlet comprises an outlet of the dialyzer.

11. The apparatus according to claim 1 , wherein the dialysate inlet comprises a peritoneal dialysis inlet and the dialysate outlet comprises a peritoneal dialysis outlet.

12. A method for reclaiming fresh dialysate from ultrafiltrate and a wasted dialysate extracted from a dialysis patient, the method comprising:
preparing an ice slurry from the wasted dialysate, wherein the ice slurry contains a plurality of ice crystals and a liquid containing solutes; and
separating the ice crystals from the liquid containing the solutes.

13. The method according to claim 12 , wherein the preparing the ice slurry from the wasted dialysate is carried out at a temperature between 0° C. and a eutectic temperature, wherein the eutectic temperature is lower than 0° C.

14. The method according to claim 12 , wherein the preparing the ice slurry from the wasted dialysate further comprises using a crystal seed and applying a crystal growth activator, wherein the crystal growth activator is glucose.

15. The method according to claim 12 , wherein the preparing the ice slurry from the wasted dialysate further comprises in supercooling.

16. The method according to claim 12 , wherein the preparing the ice slurry from the wasted dialysate further comprises controlling ice crystallization by infrared spectroscopy, Raman spectroscopy, or a combination thereof.

17. The method according to claim 12 , wherein the separating the ice crystals from the liquid further comprises cryopurifying.

18. The method according to claim 12 , wherein the wasted dialysate is recirculated.

19. The method according to claim 12 , wherein the liquid containing the solutes is analyzed like urine.

20. The method according to claim 12 , wherein the separating the ice crystals from the liquid further comprises freeze concentrating.

Assignees

• Fraunhofer Ges Forschung

Inventors

• Goldau Rainer

Classifications

• A61M1/1656 Primary

  Apparatus for preparing dialysates · CPC title

• B01D9/0004

  cooling by heat exchange (by evaporation of components of the mixture to be separated B01D9/0013; refrigeration machines F25B) · CPC title

• A61M2205/3606

  cooled · CPC title

• A61M2205/8293

  Solar · CPC title

• A61M2205/8268

  Fuel storage cells · CPC title