Corrosion resistant stent

Patent metadata

Field	Value
Publication number	US-10995398-B2
Application number	US-201815933635-A
Country	US
Kind code	B2
Filing date	Mar 23, 2018
Priority date	Jun 26, 2012
Publication date	May 4, 2021
Grant date	May 4, 2021

Abstract

A preferred embodiment is an uncoated, biodegradable stent. The stent has a filigree structure of magnesium alloy struts. The struts of the supporting structure are arranged to permit a compressed form for introduction into the body and to permit an expanded form at the site of the application within a vessel. The magnesium alloy struts are formed of a corrodible magnesium alloy. The magnesium alloy is formed from high-purity vacuum distilled magnesium containing impurities, which promote electrochemical potential differences and/or the formation of precipitations and/or intermetallic phases. The impurities are such that the struts of the stent have a tensile strength of >275 MPa a yield point of >200 MPa, a yield ratio of <0.8, a difference between tensile strength and yield point of >50 MPa.

First claim

The invention claimed is:

1. A biodegradable stent, comprising
a filigree structure of magnesium alloy struts, the struts of the filigree structure being arranged to permit a compressed form for introduction into the body and to permit an expanded form at the site of the application within a vessel;
wherein the magnesium alloy struts consist of a corrodible magnesium alloy having 2.0 to 10.0% by weight Al and a remainder consisting of vacuum distilled magnesium containing impurities in a total amount of no more than 0.0063% by weight, the alloy having solid solutions of Al and intermetallic phases of magnesium and Al in the alloy matrix, the matrix lacking Mn as an alloying element to suppress formation of the ternary intermetallic phase FeMnSi and thereby improve corrosion resistance, wherein the struts of the stent have a tensile strength of >275 MPa a yield point of >200 MPa, a yield ratio of <0.8, and a difference between tensile strength and yield point of >50 MPa.

2. The biodegradable stent of claim 1 , wherein the magnesium alloy struts have a microstructure with a grain size of <5.5 μm.

3. The biodegradable stent of claim 2 , wherein the intermetallic phases are dispersedly distributed and have a 0.5 μm particle size.

4. The biodegradable stent of claim 1 , wherein the content of Al is 2.0 to 8.0% by weight.

5. The biodegradable stent of claim 1 , wherein the impurities total no more than 0.003% by weight.

6. The biodegradable stent of claim 1 , wherein the magnesium alloy struts have a fine-grained microstructure having a grain size of no more than 7.5 μm.

7. The biodegradable stent of claim 1 , wherein the magnesium alloy struts are uncoated by any polymer passivation layer or any metal or ceramic corrosion-inhibiting coating.

8. The biodegradable stent of claim 7 , wherein the stent is an active stent.

Assignees

• Biotronik Ag

Inventors

• Mueller Heinz
• Uggowitzer Peter
• Loeffler Joerg

Classifications

• A61L27/04 Primary

  Metals or alloys · CPC title

• C22C23/04

  with zinc or cadmium as the next major constituent · CPC title

• C22C23/02 Primary

  with aluminium as the next major constituent · CPC title

• A61L31/02

  Inorganic materials · CPC title

• A61L27/58

  Materials at least partially resorbable by the body · CPC title