Neuroactive steroids, compositions, and uses thereof
US-2018215779-A1 · Aug 2, 2018 · US
17α-monoesters and 17α,21-diesters of cortexolone for use in the treatment of tumors
US10993949B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10993949-B2 |
| Application number | US-202016820407-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 16, 2020 |
| Priority date | Oct 8, 2014 |
| Publication date | May 4, 2021 |
| Grant date | May 4, 2021 |
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- Title
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Abstract
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The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of the pharmaceutical compositions as antitumor medicinal products.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treating pancreatic carcinoma in a subject in need thereof, comprising treating said subject with a therapeutically effective amount of a compound of formula: 2. The method of claim 1 , wherein the pancreatic carcinoma is exocrine pancreatic carcinoma.
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Classifications
Mouth and digestive tract, i.e. intraoral and peroral administration · CPC title
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title
- C07J5/0053Primary
not substituted in position 16 · CPC title
specific for metastasis · CPC title
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- What does patent US10993949B2 cover?
- The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceuti…
- Who is the assignee on this patent?
- Cosmo Technologies Ltd, Cosmo Tech Limited
- What technology area does this patent fall under?
- Primary CPC classification C07J5/0053. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).